Research field (2):
Food sciences
, Bioorganic chemistry
Research keywords (5):
functional food chemistry
, differentiation control of stem cells
, epigenetics
, natural products chemistry
, chemical biology
Research theme for competitive and other funds (33):
2022 - 2025 Elucidation of mechanisms for macrophage manipulation by Leishmania
2021 - 2025 Elucidation of the regulatory mechanism of feline mammary carcinoma by integrating three-dimensional culture method and pharmacokinetic analysis
2021 - 2024 Integrated platform for analyzing the modes of actions of natural products
2020 - 2024 International collaborative study on foods, microbiota, and life style diseases of Asians
2020 - 2023 Understanding microbial uncultivability: cue for the growth and incapability of colony formation
2020 - 2023 Studies of feline morbillivirus pathogenesis
2020 - 2022 Leishmania parasites as biological resources for immunomodulatory molecules
2019 - 2022 Cultivation of unculitivated microorgasnisms and clarification of growth controling mechanisms by focusing on microbial interactions
2018 - 2021 Search for small molecules controlling cell differentiation
2018 - 2020 なぜ多くの微生物は培養困難なのか?未知増殖制御メカニズムの発見と解明
2016 - 2020 Establishment and re-establishment of uterine environment for pregnancy success
2015 - 2019 Detection of chemical substances with epigenetic activity to protect environmental risk by the adverse outcome pathway approach
2014 - 2019 Development of novel methods for target identification of natural products and chemical epigenetics
2015 - 2018 Activation of protoplast function by nanobubbles and development of high-speed production system for useful metabolites
2013 - 2016 Euro-Japan collaborative field work for the understanding of symbiotic evolution of marine microbes
2014 - 2016 エピゲノム情報に基づく日本食がストレスに与える影響の評価
2013 - 2014 Analysis of stem cell differentiation process on the basis of epigenetic change
2012 - 2013 Chemical Biology on the Symbiotic System in Marine Invertebrates
2012 - 2012 Chemical Biology on the Symbiotic System in Marine Invertebrates
2009 - 2011 Research for useful marineorganisms in Asia and Pacific regions
2007 - 2009 Chemical Biology of Stem cell differentiation
2004 - 2007 海洋無脊椎動物からのガン関連酵素を標的とする機能分子の探索
2004 - 2004 ALPHASCREENによるソフトな膜タンパク質間相互作用の解析法開発
2004 - 2004 化学遺伝学的手法による血管新生阻害剤の探索
2002 - 2004 部位特異的MT1-MMP阻害剤の探索
2002 - 2003 Efficient Utilization of Fisheries Biproducts. Exploration of miomedial Resoures from Deep-Sea Spong
2002 - 2002 海洋無脊椎動物からの血管新生阻害剤の探索
2001 - 2001 海洋無脊椎動物からの血管新生阻害剤の探索
2000 - 2000 海洋無脊椎動物からの血管新生阻害剤の探索
1999 - 2000 Development of Biochemical Reagents to Study Signal Transduction from Awuatic Organisms
1998 - 1999 Discovery of Highly Selective Antifungal Agents from Marine Invertebrates
1998 - 1999 海洋無脊椎動物からの抗トロンビンリード化合物の探索
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Papers (107):
Fumiaki Nakamura, Hiroshi Kimura, Nobuhiro Fusetani, Yoichi Nakao. Two Onnamide Analogs from the Marine Sponge Theonella conica: Evaluation of Geometric Effects in the Polyene Systems on Biological Activity. Molecules. 2023
Dawoon Jung, Koshi Machida, Yoichi Nakao, Jeffrey S. Owen, Shan He, Tomonori Kindaichi, Akiyoshi Ohashi, Yoshiteru Aoi. Cultivation of previously uncultured sponge-associated bacteria using advanced cultivation techniques: A perspective on possible key mechanisms. Frontiers in Marine Science. 2022. 9
Kazuki Sasaki, Michihiro Suzuki, Takeshi Sonoda, Tilman Schneider-Poetsch, Akihiro Ito, Motoki Takagi, Shinya Fujishiro, Yoshihiro Sohtome, Kosuke Dodo, Takashi Umehara, et al. Visualization of the dynamic interaction between nucleosomal histone H3K9 tri-methylation and HP1α chromodomain in living cells. Cell Chemical Biology. 2022
Satoshi Otsuka, Midori Kawamura, Shutaro Fujino, Fumiaki Nakamura, Daisuke Arai, Nobuhiro Fusetani, Yoichi Nakao. Coronarin D, a Metabolite from the Wild Turmeric, Curcuma aromatica, Promotes the Differentiation of Neural Stem Cells into Astrocytes. Journal of agricultural and food chemistry. 2022. 70. 10. 3300-3309