Research field (1)：
Animals: biochemistry, physiology, behavioral science
Research keywords (2)：
Molecular and Cellular Biology
, 分子細胞生物学
Research theme for competitive and other funds (14)：
2020 - 2023 The new aspects of lysosomal signal regulation by Ragulator
2014 - 2016 An attempt to produce longer lifespan mouse
2012 - 2015 Reciprocal conversion between germ cells and pluripotent stem cells
2011 - 2015 Regulation of cellular function by late endosomal kinase signaling
2009 - 2011 Analysis of phosphoryl at ionsignals in regulation of stem cell system
2009 - 2010 EGFR分解におけるエンドソームERKスキャフォールドの機能解析
2005 - 2009 The Molecular basis of tyrosine kinase signaling
2003 - 2004 アクチン骨格形成におけるSrcファミリーの機能
2002 - 2004 Molecular basis of cancer diathesis
1999 - 2000 神経シナプス結合部位のChapsyn110の生理機能
1998 - 2000 Molecular Basis and Physiological Roles of Xenobiotic Exporters
1997 - 1998 NMDAレセプターのチロシンリン酸化による機能調節
1989 - Srcファミリーによる情報伝達
1989 - Signal transduction by Src family
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Papers (54)：
Soshi Noshita, Yuki Kubo, Kentaro Kajiwara, Daisuke Okuzaki, Shigeyuki Nada, Masato Okada. A TGF-β-responsive enhancer regulates SRC expression and epithelial-mesenchymal transition-associated cell migration. Journal of cell science. 2023. 136. 15
Kohei Tsujimoto, Tatsunori Jo, Daiki Nagira, Hachiro Konaka, Jeong Hoon Park, Shin-Ichiro Yoshimura, Akinori Ninomiya, Fuminori Sugihara, Takehiro Hirayama, Eri Itotagawa, et al. The lysosomal Ragulator complex activates NLRP3 inflammasome in vivo via HDAC6. The EMBO journal. 2023. 42. 1. e111389
Naoyuki Kawase, Atsuya Sugihara, Kentaro Kajiwara, Michio Hiroshima, Kanako Akamatsu, Shigeyuki Nada, Kunio Matsumoto, Masahiro Ueda, Masato Okada. SRC kinase activator CDCP1 promotes hepatocyte growth factor-induced cell migration/invasion of a subset of breast cancer cells. The Journal of biological chemistry. 2022. 298. 3. 101630-101630
Tetsuya Kimura, Yoshitomo Hayama, Daisuke Okuzaki, Shigeyuki Nada, Masato Okada. The Ragulator complex serves as a substrate-specific mTORC1 scaffold in regulating the nuclear translocation of transcription factor EB. The Journal of biological chemistry. 2022. 298. 3. 101744-101744
