Rchr
J-GLOBAL ID：200901062818834415
Update date: Nov. 15, 2024
Izumi Hiroto
イズミ ヒロト | Izumi Hiroto
Affiliation and department：
Job title：
Associate Professor
Research field (1)：
Molecular biology
Research keywords (7)：
分子腫瘍学
, 分子生物学
, 基礎生物学
, 医学
, Molecular Biology
, Basic Biology
, Medicine
Research theme for competitive and other funds (5)：
- 2023 - 2026 Development of fundamental technology for polysaccharide-nucleic acid complexes toward delivering intracellular peptides and nucleic acid adjuvants.
- がんの分子標的治療
- 薬剤耐性の分子機序
- Mechanism of angiogenesis
- mechanism of drug resistance
Papers (77)：
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Toshiki Morimoto, Hiroto Izumi, Taisuke Tomonaga, Chinatsu Nishida, Naoki Kawai, Yasuyuki Higashi, wang keyong, Ryohei Ono, Kazuki Sumiya, Kazuo Sakurai, et al. The effects of endoplasmic reticulum stress via intratracheal instillation of water-soluble acrylic acid polymer on the lungs of rats. International Journal of Molecular Sciences. 2024
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Chinatsu Nishida, Taisuke Tomonaga, Hiroto Izumi, Ke-Yong Wang, Hidenori Higashi, Toru Ishidao, Jun-ichi Takeshita, Ryohei Ono, Kazuki Sumiya, Shota Fujii, et al. Inflammogenic effect of polyacrylic acid in rat lung following intratracheal instillation. Particle and Fibre Toxicology. 2022. 19. 1. 8-8
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Taisuke Tomonaga, Chinatsu Nishida, Hiroto Izumi, Naoki Kawai, Ke-Yong Wang, Hidenori Higashi, Jun-Ichi Takeshita, Ryohei Ono, Kazuki Sumiya, Shota Fujii, et al. Crosslinked Structure of Polyacrylic Acid Affects Pulmonary Fibrogenicity in Rats. International Journal of Molecular Sciences. 2022. 23. 22. 13870-13870
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Chinatsu Nishida, Hiroto Izumi, Taisuke Tomonaga, Ke-Yong Wang, Hidenori Higashi, Jun-Ichi Takeshita, Ryohei Ono, Kazuki Sumiya, Shota Fujii, Yuki Hata, et al. Effect of Different Molecular Weights of Polyacrylic Acid on Rat Lung Following Intratracheal Instillation. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022. 23. 18
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Chinatsu Nishida, Hiroto Izumi, Taisuke Tomonaga, Jun-Ichi Takeshita, Ke-Yong Wang, Kei Yamasaki, Kazuhiro Yatera, Yasuo Morimoto. Predictive Biomarkers for the Ranking of Pulmonary Toxicity of Nanomaterials. Nanomaterials (Basel, Switzerland). 2020. 10. 10
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MISC (71)：
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Tomohiro Shibata, Hiroto Izumi, Akihiko Kawahara, Satoshi Hattori, Chihiro Fukumitsu, Ryuji Takahashi, Kosuke Watari, Yuichi Murakami, Kimitoshi Kohno, Ken-ichi Ito, et al. Y-box binding protein-1 YB-1 negatively regulates ER alpha expression accompanying by enhanced HER2/ErbB2 expression in breast cancer. CANCER RESEARCH. 2014. 74. 19
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Hiroto Izumi, Keyong Wang, Yasuo Morimoto, Yasuyuki Sasaguri, Kimitoshi Kohno. Circadian disruption and cancer risk: A new concept of stromal niche (Review). International Journal of Oncology. 2014. 44. 2. 364-370
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Koichi Azuma, Akihiko Kawahara, Kahori Sonoda, Kazutaka Nakashima, Kousuke Tashiro, Kosuke Watari, Hiroto Izumi, Masayoshi Kage, Michihiko Kuwano, Mayumi Ono, et al. FGFR1 activation is an escape mechanism in human lung cancer cells resistant to afatinib, a pan-EGFR family kinase inhibitor. Oncotarget. 2014. 5. 15. 5908-5919
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Koichi Azuma, Akihiko Kawahara, Satoshi Hattori, Tomoki Taira, Junji Tsurutani, Kosuke Watari, Tomohiro Shibata, Yuichi Murakami, Shinzo Takamori, Mayumi Ono, et al. NDRG1/Cap43/Drg-1 may predict tumor angiogenesis and poor outcome in patients with lung cancer. Journal of Thoracic Oncology. 2012. 7. 5. 779-789
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秋山 正樹, 和泉 弘人, 柏木 英志, 安庭 義浩, Han Bin, Wu Ying, 内海 健, 荒尾 徳三, 西尾 和人, 河野 公俊. 転写因子ZNF143によるDNA複製および細胞周期関連因子の発現制御と腫瘍増殖(Role of ZNF143 in tumor growth through transcriptional regulation of DNA replication and cell cycle associated genes). 日本癌学会総会記事. 2010. 69回. 173-173
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Education (4)：
- - 1996 Oita Medical University
- - 1996 Oita Medical University Graduate School, Division of Medicine
- - 1988 Oita Medical University
- - 1988 Oita Medical University Faculty of Medicine
Professional career (1)：
Work history (4)：
- 2013/04 - 現在 University of Occupational and Environmental Health, Japan Department of Occupational Pneumology, Institute of Industrial Ecological Sciences Associate Professor
- 2004/04 - University of Occupational and Environmental Health, Japan
- 2001/04 - University of Occupational and Environmental Health, Japan
- 1996/08 - University of Occupational and Environmental Health, Japan
Association Membership(s) (6)：
日本整形外科学会
, 日本細胞生物学会
, AACR
, 分子生物学会
, 日本生化学会
, 日本癌学会
