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J-GLOBAL ID：200901062818834415   Update date: Mar. 19, 2025

Izumi Hiroto

イズミ ヒロト | Izumi Hiroto
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Affiliation and department：
University of Occupational and Environmental Health, Japan Department of Occupational Pneumology, Institute of Industrial Ecological Sciences

About University of Occupational and Environmental Health, Japan Department of Occupational Pneumology, Institute of Industrial Ecological Sciences


Job title： Associate Professor
Research field  (1)： Molecular biology
Research keywords  (7)： 分子腫瘍学 ,  分子生物学 ,  基礎生物学 ,  医学 ,  Molecular Biology ,  Basic Biology ,  Medicine
Research theme for competitive and other funds  (5)：
  • 2023 - 2026 Development of fundamental technology for polysaccharide-nucleic acid complexes toward delivering intracellular peptides and nucleic acid adjuvants.
  • がんの分子標的治療
  • 薬剤耐性の分子機序
  • Mechanism of angiogenesis
  • mechanism of drug resistance
Papers (98)：
  • Taisuke Tomonaga, Hidenori Higashi, Hiroto Izumi, Chinatsu Nishida, Kazuma Sato, Yuiko Nakamura, Toshiki Morimoto, Yasuyuki Higashi, Takuma Kojima, Kazuo Sakurai, et al. Comparison of lung disorders following intratracheal instillation of polystyrene microplastics with different surface functional groups. Journal of occupational health. 2025
  • Taisuke Tomonaga, Hiroto Izumi, Chinatsu Nishida, Kazuma Sato, Yuiko Nakamura, Toshiki Morimoto, Yasuyuki Higashi, Ke-Yong Wang, Hidenori Higashi, Takuma Kojima, et al. The degree of cross-linking of polyacrylic acid affects the fibrogenicity in rat lungs. Scientific reports. 2025. 15. 1. 3514-3514
  • Yasuo Morimoto, Hiroto Izumi, Taisuke Tomonaga, Chinatsu Nishida, Hidenori Higashi. Adverse effects of nanoparticles on humans. Journal of occupational health. 2025. 67. 1
  • Yasuyuki Higashi, Chinatsu Nishida, Hiroto Izumi, Kazuma Sato, Naoki Kawai, Taisuke Tomonaga, Toshiki Morimoto, Kei Yamasaki, Ke-Yong Wang, Hidenori Higashi, et al. Inhalation exposure to cross-linked polyacrylic acid induces pulmonary disorders. Toxicology. 2025. 510. 154001-154001
  • 友永 泰介, 和泉 弘人, 川合 直紀, 佐藤 和真, 西田 千夏, 東 秀憲, 森本 俊規, 東 泰幸, 矢寺 和博, 森本 泰夫. アクリル酸系高分子化合物の肺障害における物理化学的特性の影響. 日本肺サーファクタント・界面医学会雑誌. 2024. 55. 31-33
ｍore...
MISC (71)：
  • Tomohiro Shibata, Hiroto Izumi, Akihiko Kawahara, Satoshi Hattori, Chihiro Fukumitsu, Ryuji Takahashi, Kosuke Watari, Yuichi Murakami, Kimitoshi Kohno, Ken-ichi Ito, et al. Y-box binding protein-1 YB-1 negatively regulates ER alpha expression accompanying by enhanced HER2/ErbB2 expression in breast cancer. CANCER RESEARCH. 2014. 74. 19
  • Hiroto Izumi, Keyong Wang, Yasuo Morimoto, Yasuyuki Sasaguri, Kimitoshi Kohno. Circadian disruption and cancer risk: A new concept of stromal niche (Review). International Journal of Oncology. 2014. 44. 2. 364-370
  • Koichi Azuma, Akihiko Kawahara, Kahori Sonoda, Kazutaka Nakashima, Kousuke Tashiro, Kosuke Watari, Hiroto Izumi, Masayoshi Kage, Michihiko Kuwano, Mayumi Ono, et al. FGFR1 activation is an escape mechanism in human lung cancer cells resistant to afatinib, a pan-EGFR family kinase inhibitor. Oncotarget. 2014. 5. 15. 5908-5919
  • Koichi Azuma, Akihiko Kawahara, Satoshi Hattori, Tomoki Taira, Junji Tsurutani, Kosuke Watari, Tomohiro Shibata, Yuichi Murakami, Shinzo Takamori, Mayumi Ono, et al. NDRG1/Cap43/Drg-1 may predict tumor angiogenesis and poor outcome in patients with lung cancer. Journal of Thoracic Oncology. 2012. 7. 5. 779-789
  • 秋山 正樹, 和泉 弘人, 柏木 英志, 安庭 義浩, Han Bin, Wu Ying, 内海 健, 荒尾 徳三, 西尾 和人, 河野 公俊. 転写因子ZNF143によるDNA複製および細胞周期関連因子の発現制御と腫瘍増殖(Role of ZNF143 in tumor growth through transcriptional regulation of DNA replication and cell cycle associated genes). 日本癌学会総会記事. 2010. 69回. 173-173
ｍore...
Education (4)：
  • - 1996 Oita Medical University
  • - 1996 Oita Medical University Graduate School, Division of Medicine
  • - 1988 Oita Medical University
  • - 1988 Oita Medical University Faculty of Medicine
Professional career (1)：
  • (BLANK)
Work history (4)：
  • 2013/04 - 現在 University of Occupational and Environmental Health, Japan Department of Occupational Pneumology, Institute of Industrial Ecological Sciences Associate Professor
  • 2004/04 - University of Occupational and Environmental Health, Japan
  • 2001/04 - University of Occupational and Environmental Health, Japan
  • 1996/08 - University of Occupational and Environmental Health, Japan
Association Membership(s) (6)：
日本整形外科学会 ,  日本細胞生物学会 ,  AACR ,  分子生物学会 ,  日本生化学会 ,  日本癌学会
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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