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J-GLOBAL ID：200901064023164562 Update date: Feb. 02, 2025

Manome Yoshinobu

マノメヨシノブ | Manome Yoshinobu

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Affiliation and department：
Job title： Professor

Research field (5)： Neuropathology , Cell biology , Molecular biology , Biomaterials , Biomedical engineering

Research keywords (3)： Biomedical Engineering , Neuroscience , Molecular cell Biology

Research theme for competitive and other funds (16)：

2022 - 2025 ランゲルハンス細胞と知覚神経C線維の関係-褥瘡モデルマウスによる神経解剖学的解析
2021 - 2024 Antibacterial and antivirus properties of copper doped carbon film
2019 - 2023 酸化ストレスと知覚神経過伸長の関係-褥瘡圧迫モデルマウスによる神経解剖学的研究
2018 - 2021 High-performance biomaterial with essential metal ions to supply to in the living body
2017 - 2021 Novel liquid embolic materials for brain endovascular therapy: natural polymer composite activated by blood calcium ions

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Papers (68)：

Erika Osada, Yoshinobu Manome, Yohei Sato. A dataset on NFKB1/NFKB2 knockout Jurkat cells and primary CD4+ T cells generated by CRISPR/Cas9 mediated gene disruption. Data in Brief. 2025. 111359-111359
Yohei Sato, Erika Osada, Yoshinobu Manome. Non-canonical NFKB signaling endows suppressive function through FOXP3-dependent regulatory T cell program. Heliyon. 2023. 9. 12. e22911
伏見淳, 武山浩, 立花利公, 馬目佳信. 乳癌細胞株での骨芽細胞分化試薬による胎盤型アルカリホファターゼを介した石灰化誘導. 日本乳癌学会総会プログラム抄録集. 2022. 30回. np66-np66
Muneyuki Koyama, Erika Osada, Nubutake Akiyama, Ken Eto, Yoshinobu Manome. Effect of Thymidine Phosphorylase Gene Demethylation on Sensitivity to 5-Fluorouracil in Colorectal Cancer Cells. Anticancer research. 2022. 42. 2. 837-844
小山能徹, 長田恵梨香, 秋山暢丈, 馬目佳信. 遺伝子promoter領域の脱メチル化によるthymidine phosphorylase発現レベルの変動が大腸癌のフッ化ピリミジン系薬剤感受性に与える影響. 東京慈恵会医科大学雑誌. 2021. 136. 6. 132-133

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MISC (164)：

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Books (2)：

Ultrasonic transduction of DNA into central nervous system cells.pp100-103AIP conference proceedings Vol.754, 4th International Symposium on Therapeutic ultrasound.
American Institute of Physics. Edited by G.R.ter Haar and I. Rivens. 2005 ISBN:0735402396
日本遺伝子治療学会編遺伝子治療開発研究ハンドブック第1章第5節 2.虚血性心疾患、とくに冠状動脈狭窄性病変に対する血管形成術後の再狭窄pp233-236
エヌ・テイー・エス 1999 ISBN:4900830380

Lectures and oral presentations (7)：

Morphologic characterization of human glioma cells in three-dimensional cell culture
(9th Asia-Pacific Microscopy Conference (APMC9) 2008)
Three-dimensional cell culture of human glioma cells and morphological differences.
(Eighth International Conference of Anticancer Research. 2008)
Development and application of a thyroid specific monoclonal antibody.
(Eighth International Conference of Anticancer Research 2008)
Utilization of caspase 14 promoter for selective transgene expression in squamous layers of cholesteatoma in the middle ear.
(The 14th annual meeting 2008. Japan Society of Gene Therapy 2008)
Transduction of siRNA against ROCK1 and ROCK2 causes different effects on glomerular mesengial cells in diabetic condition model.
(The 14th annual meeting 2008. Japan Society of Gene Therapy 2008)

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Education (3)：

2016 - 2017 Kanazawa Institute of Technology Toranomon Graduate Schoo MBA Program
1984 - 1990 Jikei University School of Medicine Neurosurgery
1976 - 1982 Kyoto Prefectural University of Medicine Medicine

Professional career (1)：

(BLANK) (Jikei University)

Work history (5)：

2014/04 - 現在 Jikei University School of Medicine Core Research Facilities Professor
2008/01 - 2014/03 Jikei University Shool of Medicine Department of Molecular Cell Biology Professor
2003/12 - 2007/12 Jikei University School of Medicine Department of Molecular Cell Biology Associate Professor
1996/10 - 2003/11 Jikei University School of Medicine The 1st department of microbiology Lecturer
1990 - 1996 Jikei University School of Medicine, Research Assistant Department of Neurosurgery Associate

Association Membership(s) (4)：

Japan Society for Occupational Health , Japan Neurosurgical Society , Japan Society of Gene and Cell Therapy , Japanese Society for Medical and Biological Engineering

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