Rchr
J-GLOBAL ID：200901065330368090
Update date: Jun. 25, 2024
Hiroshi Kurosawa
クロサワ ヒロシ | Hiroshi Kurosawa
Affiliation and department：
Job title：
Executive Director (Vice -President)
Homepage URL (1)：
http://www.bt.yamanashi.ac.jp/modules/kyoin/
Research field (3)：
Chemical reaction and process system engineering
, Applied microbiology
, Biomedical engineering
Research theme for competitive and other funds (15)：
- 2021 - 2024 ヒトiPS細胞の革新的な非凍結密閉系保存技術の開発
- 2021 - 2024 ヒトiPS細胞に有効で熱安定性の高い環状ペプチド型bFGF代替物の創製
- 2019 - 2022 細胞非自律的に作用する遺伝子の網羅的同定法開発
- 2014 - 2017 Development of a novel culture method for obtaining human iPS cells with high pluripotency
- 2011 - 2014 Development epigenomic restoration therapy for autistic disorders
- 2009 - 2011 Control of the differentiation pluripotent stem cells(ES・iPS cells) by culture surface coated with functional compounds.
- 2006 - 2007 Standardization of embryoid body formation from embryonic stem cellsand quality estimation of embryoid bodies
- 2003 - 2004 The elucidation of the physiochemical factor of the mouse ES cell on the ambryoid body formation.
- 2003 - 2003 組織工学的アプローチによる新規バイオミメティック組織デバイス開発の現状と課題
- 2002 - 2002 ティッシュエンジニアリングによる組織再生の医療応用における工学的課題調査
- 2001 - 2001 化学・生物工学的観点からの組織工学のポテンシャル評価-再生医療技術に関する分野横断的研究動向の調査-
- 1999 - 2000 肝細胞の簡便迅速な高密度充填が可能な新規細胞支持基材を用いた人工肝臓の開発
- 1997 - 1998 Elucidation of acid tolerant function of Thiobacillus thiooxidans grown under scid and extreme environment
- 1996 - 1996 細菌由来の耐酸性因子を再構成して得られる酸防御機構を備えた生体模擬システム
- 1995 - 1996 Elucidation of sulfate-dependent acid phosphatase from Thiobacillus thiooxidans and determination of sulfate in waters using whole cells
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Papers (18)：
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Takahiro Anzai, Shinji Saijou, Yoshitsugu Ohnuki, Hiroshi Kurosawa, Masahiro Yasunaga, Yasuhiro Matsumura. TMEM180 contributes to SW480 human colorectal cancer cell proliferation through intra-cellular metabolic pathways. Translational Oncology. 2021. 14. 10. 101186-101186
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Kiyomi Yoda, Yoshitsugu Ohnuki, Shinji Masui, Hiroshi Kurosawa. Optimized conditions for the supplementation of human-induced pluripotent stem cell cultures with a GSK-3 inhibitor during embryoid body formation with the aim of inducing differentiation into mesodermal and cardiac lineage. JOURNAL OF BIOSCIENCE AND BIOENGINEERING. 2020. 129. 3. 371-378
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Kiyomi Yoda, Yoshitsugu Ohnuki, Hiroshi Kurosawa. Optimization of the treatment conditions with glycogen synthase kinase-3 inhibitor towards enhancing the proliferation of human induced pluripotent stem cells while maintaining an undifferentiated state under feeder-free conditions. JOURNAL OF BIOSCIENCE AND BIOENGINEERING. 2019. 127. 3. 381-387
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Yoshitsugu Ohnuki, Takumi Kondo, Hiroshi Kurosawa. ROCK inhibitor Y-27632 used during cell aggregate formation adversely affects the early cardiac differentiation on human iPS cells. Tissue Culture Research Communications. 2017. 36. 21-29
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Tomoko Andoh-Noda, Wado Akamatsu, Kunio Miyake, Tetsuro Kobayashi, Manabu Ohyama, Hiroshi Kurosawa, Takeo Kubota, Hideyuki Okano. Differential X chromosome inactivation patterns during the propagation of human induced pluripotent stem cells. Keio Journal of Medicine. 2017. 66. 1. 1-8
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Books (1)：
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第9章 動物細胞培養系における酸素供給と酸素消費
シーエムシー出版 2021
Lectures and oral presentations (9)：
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Novel Cyclic N-alkyl Peptide Dimers as bFGF Mimetics to Maintain thePluripotency of Human Induced Pluripotent Stem Cells
(日本組織培養学会 第93回大会 2021)
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Primitive endoderm cells promote proliferation and differentiation of pluripotent stem cells.
(JAACT2020 Fuchu 2020)
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Screening of molecule that facilitate transition from mouse embryonic stem cells to early-embryonic-like cells.
(JAACT2020 Fuchu 2020)
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Novel cyclic N-alkyl peptides as bFGF mimetics to maintain the pluripotency of human induced pluripotent stem cells.
(JAACT2020 Fuchu 2020)
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Ultra-high-throughput screening and function analysis of novel cyclic N-alkyl peptides for the proliferation of human iPS cells in undifferentiated state as artificial FGFR agonists.
(第71回(2019年)日本生物工学会大会 2019)
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Professional career (2)：
- ph.D. (University of Tsukuba)
- 学術博士 (筑波大学)
Committee career (6)：
Association Membership(s) (2)：
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