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J-GLOBAL ID：200901067390634671 Update date: Dec. 18, 2024

Yoshida Akihiro

Affiliation and department：
Job title： Research Scientist

Research field (4)： Pharmaceuticals - chemistry and drug development , Synthetic organic chemistry , Bioorganic chemistry , Structural/physical organic chemistry

Research keywords (13)：反応場 , 環境調和型反応 , 選択的合成・反応 , 不斉合成 , 触媒設計・反応 , 有機金属触媒 , 有機金属化学 , 合成有機化学 , Stereoselective Synthesis , Lanthanide , Lewis Acid , Organometallic Chemistry , Synthetic Organic Chemistry

Research theme for competitive and other funds (8)：

2007 - 2011 グリーンケミストリーを指向したフルオラスおよび磁性触媒反応の開発研究
2004 - 2007 フルオラス及びイオン性液体中の超ルイス酸・塩基複合系触媒反応の開拓とリサイクル化
2001 - 2003 ランタニド反応剤の特性を活用した新規連続的および不斉合成反応の開発
2001 - 2002 DMA Lesions on the Specific Site in the Transcription Factor Binding Domain with RecA-Oligonucleotide Complexes
2002 - Development of fluorous Lewis acids-catalyzed reactions in fluorous biphasic, aqueous, scCO2, and ionic liquid systems.

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Papers (27)：

Taro Koda, Hiroshi Akutsu, Mitsuaki Suzuki, Kosuke Nakashima, Shin-ichi Hirashima, Akihiro Yoshida, Tsuyoshi Miura, Takashi Yamanoi. Asymmetric ε-regioselective conjugate addition of 2-furfuryl ketones to nitroalkenes using a thiourea organocatalyst. Tetrahedron Letters. 2025. 155. 155392-155392
Eri Sasaki, Yoshihiro Hayashi, Yuka Kimura, Sanae Sashida, Nobuhito Hamano, Kei Nirasawa, Keisuke Hamada, Fumihiko Katagiri, Yamato Kikkawa, Takaaki Sakai, et al. Alpha-dystroglycan binding peptide A2G80-modified stealth liposomes as a muscle-targeting carrier for Duchenne muscular dystrophy. Journal of Controlled Release. 2021. 329. 1037-1045
Takashi Yamanoi, Yoshiki Oda, Akihiko Koizumi, Tsubasa Kawaguchi, Shin Yagihara, Akihiro Yoshida. α-Glucoside Formation from 2-Deoxy-2-(2,2,2-trichloroethoxycarboxamido)-α-D-glucopyranosyl Acetate Using an Activating System That Used a Combination of Ytterbium(III) Triflate and a Catalytic Boron Trifluoride Diethyl Etherate Complex. HETEROCYCLES. 2019. 99. 2. 834-834
Takashi Yamanoi, Ryo Inoue, Yoshiki Oda, Akihiro Yoshida. Use and Recyclability of Scandium Tris[bis(perfluorooctylsulfonyl)amide] As A Lewis Acid Promoter for Glycosidation Reactions. Letters in Organic Chemistry. 2018. 15. 12. 1056-1059
Ali Keivanloo, Tayebeh Besharati-Seidani, Babak Kaboudin, Akihiro Yoshida, Tsutomu Yokomatsu. One-pot synthesis of biologically active 1,2,3-trisubstituted pyrrolo[2,3-b]quinoxalines through a palladium-catalyzed reaction with internal alkyne moieties. Molecular Diversity. 2018. 22. 4. 879-891

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MISC (93)：

林由浩, 佐々木愛理, 木村優花, 韮沢慧, 濱野展人, 片桐文彦, 坂井崇亮, 吉田彰宏, 平島真一, 三浦剛, et al. A2G80ペプチド修飾リポソームの全身投与による筋組織移行性評価. 日本薬剤学会年会講演要旨集. 2019. 34年会. 182-182
Akihiro Yoshida. Development of Fluorous Lewis Acid-Catalyzed Reactions. Fluorine. 2011. 3. 2. 10-16
Takashi Yamanoi, Ryo Inoue, Sho Matsuda, Kazuya Iwao, Yoshiki Oda, Akihiro Yoshida, Keita Hamasaki. FORMATION OF O-GLYCOSIDIC LINKAGES FROM 1-HYDROXY SUGARS BY BISMUTH(III) TRIFLATE-CATALYZED DEHYDRATIVE GLYCOSIDATION. HETEROCYCLES. 2009. 77. 1. 445-460
Synthesis of exo-Glycals from 1-C-Vinyl-D-glycopyranose via an SN1’-Substitution Mechanism and Their Spirocyclization to Give [6,6]-Spiroketals. XXIV International Carbohydrate Symposium (ICS 2008). 2008
Synthesis of exo-Glycals from 1-C-Vinyl-D-glycopyranose via an SN1’-Substitution Mechanism and Their Spirocyclization to Give [6,6]-Spiroketals. XXIV International Carbohydrate Symposium (ICS 2008). 2008

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Patents (13)：

フルオラス化糖結合型クラウンエーテル誘導体
低リーチング性のフルオラス多相系反応方法
ポリエーテル系フルオラス溶媒を用いたフルオラス多相系反応方法
路易斯酸催化剤組合物
Lewis-Säure-Katalysatorzusammensetzung

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Books (6)：

触媒の設計・反応制御事例集-高活性、長寿命、低コスト化の実現-
技術情報協会 2013
Base and Application of Fluorous Chemistry
2010 ISBN:9784781302782
「固定化触媒のルネッサンス」,第15章
シーエムシー出版 2007 ISBN:9784882319412
Renaissance of Immobilized Catalyst
CMC Publishing 2007 ISBN:9784882319412
「フルオラスケミストリー」,第III編第5章
シーエムシー出版 2005 ISBN:4882315319

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Lectures and oral presentations (3)：

フルオラスLewis酸触媒反応の開発-温暖化とPFOS/PFOA問題への対応-
(第29回有機合成化学セミナー 2012)
Development of Lewis Acid-Catalyzed Reactions Based on Fluorous Chemistry
(2010)
フルオラスLewis酸触媒反応の開発
(第17回有機フッ素化学セミナー(岡山)その2 2010)

Education (6)：

- 1997 Tokyo Institute of Technology Science of Engineering Chemical Engineering
- 1997 Tokyo Institute of Technology Graduate School, Division of Science and Engineering Applied Chemistry
- 1995 Tokyo Institute of Technology Science of Engineering Chemical Engineering
- 1995 Tokyo Institute of Technology Graduate School, Division of Science and Engineering Applied Chemistry
- 1993 Tokyo Institute of Technology School of Engineering Dept. of Chemical Engineering

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Professional career (1)：

Doctor(Engineering) (Tokyo Institute of Technology)

Awards (2)：

2000 - 手島記念研究賞博士論文賞
2000 - Tejima Memorial Research Award (for outstanding Ph.D. thesis)

Association Membership(s) (6)：

日本薬学会 , 有機合成化学協会 , 日本化学会 , The Pharmaceutical Society of Japan , The Society of Synthetic Organic Chemistry, Japan , The Chemical Society of Japan

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