Rchr
J-GLOBAL ID:200901068680246400
Update date: Sep. 08, 2024
Maekawa Keiko
マエカワ ケイコ | Maekawa Keiko
Affiliation and department:
Job title:
Professor
Research field (2):
Pharmacology
, Pharmaceuticals - health and biochemistry
Research keywords (2):
薬理学
, Pharmacology
Research theme for competitive and other funds (12):
- 2022 - 2025 多発性骨髄腫における抗腫瘍免疫回避の機序解明を目的とした血漿の網羅的解析
- 2020 - 2023 Development of prediction and evaluation methods of KIE involving drug-metabolizing enzymes for deuterated drug design
- 2020 - 2023 Deuterium Science
- 2019 - 2023 血清オミックス解析を中心とした多発性骨髄腫の治療薬レナリドミドの感受性因子の探索
- 2018 - 2023 Effects of multiple binding sites of CYP2C9 on its allosteric modulation
- 2016 - 2020 Identification of blood biomarkers predicting clinical efficacy of molecular targeting agents in multiple myeloma
- 2015 - 2017 血中の抗炎症性脂質により腫瘍が分子標的薬に高感受性を示す作用機序
- 2013 - 2017 Elucidation on pathophysiological significance of orphan P450 expression in tumor tissue and its application to drug discovery research
- 2012 - 2015 Reverse omics analysis for mechanisms on hand-foot syndrome and predictive system construction.
- 2010 - 2012 Structure-activity relationship studies of CYP2C9 genetic variants
- 2001 - 2004 薬剤反応性遺伝子の一塩基多型に関する研究
- 2001 - 2004 Genetic variation of human gene related to drug methaholism
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Papers (108):
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Eri Tsukagoshi, Ryosuke Nakamura, Yoichi Tanaka, Keiko Maekawa, Masahiro Hiratsuka, Hideo Asada, Yoshiro Saito. Validation of a genotyping technique for a surrogate marker of HLA-B58:01 for allopurinol-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in the Japanese population. Drug Metabolism and Pharmacokinetics. 2023. 49. 100495-100495
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Ryosuke Nakamura, Noriaki Arakawa, Yoichi Tanaka, Nahoko Uchiyama, Akihiro Sekine, Yoichi Mashimo, Keiji Tsuji, Tatehiro Kagawa, Ken Sato, Masaaki Watanabe, et al. Significant association between HLA-B*35:01 and onset of drug-induced liver injury caused by Kampo medicines in Japanese. Hepatology research : the official journal of the Japan Society of Hepatology. 2022. 53. 5. 440-449
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Keiko Maekawa, Masahiro Yamamura, Atsushi Matsuki, Takashi Ishikawa, Toshihiro Hirai, Yoshiyuki Yamaguchi, Yoshiro Saito, Tatsuo Kanda. Impacts of SNPs on adverse events and trough concentration of imatinib in patients with gastrointestinal stromal tumors. Drug metabolism and pharmacokinetics. 2022. 43. 100441-100441
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Mika Maeda, Rieko Tanaka, Masako Aso, Yasutoshi Sakamoto, Ildae Song, Michiru Ochiai, Yoshiro Saito, Keiko Maekawa, Noriaki Arakawa, Yasuo Ohno, et al. Hepatic Adaptation to Therapeutic Doses of Acetaminophen: An Exploratory Study in Healthy Individuals. Clinical therapeutics. 2020. 42. 7. 1276-1291
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Masahiro Tohkin, Yoshiro Saito, Satomi Yagi, Kunihito Asano, Keiko Maekawa, Makoto Osabe, Shinsuke Iida, Naoki Miyata. Clinical study designs and patient selection methods based on genomic biomarkers: Points-to-consider documents. Drug metabolism and pharmacokinetics. 2020. 35. 2. 187-190
more...
MISC (42):
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Kosuke Saito, Masaki Ishikawa, Hiroshi Yamada, Noriyuki Nakatsu, Keiko Maekawa, Yoshiro Saito. PLASMA LIPID PROFILING OF CHEMICAL-INDUCED LIVER INJURIES. DRUG METABOLISM AND PHARMACOKINETICS. 2017. 32. 1. S33-S33
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Yoshiro Saito, Keiko Maekawa, Ryosuke Nakamura. Use of PGx information for prediction of severe adverse drug reactions: Current status and future perspectives. ANNALS OF ONCOLOGY. 2016. 27
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Kosuke Saito, Masaki Ishikawa, Hiroshi Yamada, Noriyuki Nakatsu, Keiko Maekawa, Yoshiro Saito. Liver lipid profiling of chemical-induced phospholipidosis. FASEB JOURNAL. 2016. 30
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桶本 和男, 前川 京子, 田島 陽子, 頭金 正博, 齋藤 嘉朗. 性別、年齢、およびBMIによるヒト尿中リピドームの交差分類(Cross-classification of human urinary lipidome by gender, age, and body mass index). 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集. 2015. 88回・38回. [1LBA078]-[1LBA078]
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Yoshiro Saito, Keiko Maekawa, Kosuke Saito, Masaki Ishikawa, Akiyoshi Hirayama, Tomoyoshi Soga. METABOLOMICS-BASED ANALYSES ON DILATED CARDIOMYOPATHY AND ALZHEIMER'S DISEASE. DRUG METABOLISM REVIEWS. 2015. 47. 17-17
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Education (4):
- - 1994 Kyoto University
- - 1994 Kyoto University Graduate School, Division of Pharmaceutical Sciences Pharmacology
- - 1992 Kyoto University Faculty of Pharmaceutical Sciences
- - 1992 Kyoto University Faculty of Pharmaceutical Science Pharmacy
Professional career (1):
- Doctor(Pharmacy) (Kyoto University)
Work history (2):
- 1994 - 2002 国立医薬品食品衛生研究所 研究員
- 1994 - 2002 Researcher, National Ins. Health Sciences
Association Membership(s) (2):
日本薬理学会
, The Japanese Pharmacological Society
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