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J-GLOBAL ID:200901069048544159   Update date: Mar. 09, 2025

Yano Seiji

ヤノ セイジ | Yano Seiji
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Affiliation and department:
Job title: Professor
Other affiliations (1):
  • Kanazawa University  Nano Life Science Institute 
Research field  (1): Respiratory medicine
Research keywords  (3): Brain metastasis ,  Targeted drug resistance ,  Lung cancer
Research theme for competitive and other funds  (29):
  • 2023 - 2026 Study to form a theoretical basis for personalized medicine that stratifies EGFR-mutated lung cancer by co-mutations
  • 2019 - 2021 分子標的薬で肺がんの根治を目指す治療の非臨床研究基盤の形成
  • 2016 - 2021 MAPKシグナル抑制が誘導するフィードバック機構の不均一性解明と制御に基づくKRAS/BRAF変異腫瘍に対する新規治療開発
  • 2018 - 2020 RET肺がんに対するアレクチニブの医師主導治験と耐性機構解析
  • 2016 - 2019 Combined treatment of hyperthermia therapy using novel ferromagnet and mTOR inhibitor for malignant pleural mesothelioma
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Papers (445):
  • Yuichi Tambo, Takashi Sone, Koichi Nishi, Kazuhiko Shibata, Toshiyuki Kita, Tomoyuki Araya, Hiroki Shirasaki, Takahiro Shimizu, Taro Yoneda, Hiroki Matsuoka, et al. Five-year efficacy and safety of pembrolizumab as first-line treatment in patients with non-small cell lung cancer with PD-L1 tumor proportion score ≥50 %: A multicenter observational study. Lung cancer (Amsterdam, Netherlands). 2025. 201. 108422-108422
  • Koushiro Ohtsubo, Kunio Miyake, Shigeki Sato, Hiroyuki Sakaguchi, Koji Fukuda, Hiroshi Kotani, Akihiro Nishiyama, Shigeki Nanjo, Kaname Yamashita, Shinji Takeuchi, et al. Analysis of Methylation of Tumor-suppressive miRNAs and KRAS/TP53 Mutations in Pancreatic Juice. Anticancer research. 2024. 44. 12. 5253-5261
  • Nanao Terada, Hayato Koba, Shigeki Nanjo, Hideharu Kimura, Akihiro Nishiyama, Taro Yoneda, Takayuki Takeda, Hiroki Shirasaki, Koichi Nishi, Takashi Sone, et al. EGFR-V834L combined with L858R mutation reduced afatinib sensitivity and associated to early recurrence in lung cancer. Translational lung cancer research. 2024. 13. 11. 3067-3082
  • Yuki Katayama, Tadaaki Yamada, Keiko Tanimura, Hayato Kawachi, Masaki Ishida, Yohei Matsui, Soichi Hirai, Ryota Nakamura, Kenji Morimoto, Naoki Furuya, et al. YAP regulates HER3 signaling-driven adaptive resistance to RET inhibitors in RET-aberrant cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2024
  • Yohei Asano, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Satoshi Kato, Shinji Miwa, Miho Okuda, Isao Matsumoto, Seiji Yano, Satoru Demura. Serum Inflammatory Dynamics as Novel Biomarkers for Immune Checkpoint Inhibitors in Non-small-cell Lung Cancer With Bone Metastases. Anticancer research. 2024. 44. 10. 4493-4503
more...
MISC (348):
  • Watanabe Satoshi, Kase Kazumasa, Saeki Keigo, Kobayashi Takafumi, Takeda Yoshihiro, Ohkura Noriyuki, Abo Miki, Horie Masafumi, Naito Hisamichi, Yano Seiji. Monocyte-derived Interstitial Macrophages Stimulate Angiogenesis to Promote Lung Regeneration following Pneumonectomy. 日本呼吸器学会誌. 2024. 13. 増刊. 388-388
  • 武藤篤, 山村健太, 原椋, 村瀬裕哉, 上田宰, 古林崇史, 加瀬一政, 武田仁浩, 寺田七朗, 木場隼人, et al. 気管支鏡検査で診断しえた微小肺髄膜腫様結節の1例. 気管支学. 2024. 46
  • 原椋, 渡辺知志, 村瀬裕哉, 上田宰, 古林崇史, 武藤篤, 加瀬一政, 武田仁浩, 寺田七朗, 木場隼人, et al. びまん性肺病変に対しクライオ生検で診断し得た肺腺癌の2例. 気管支学. 2024. 46
  • 築田紗矢, 渡辺知志, 清家悠樹, 原椋, 村瀬裕哉, 本江真人, 山本祥博, 寺田七朗, 木場隼人, 矢野聖二. 免疫チェックポイント阻害薬による肺障害発症リスク因子の検討. 日本内科学会雑誌. 2023. 112
  • 渡辺知志, 加瀬一政, 佐伯啓吾, 古林崇史, 武田仁浩, 大倉徳幸, 阿保未来, 堀家慎一, 内藤尚道, 矢野聖二. Monocyte-derived interstitial macrophages stimulate angiogenesis and promote lung regeneration. 日本呼吸器学会誌(Web). 2023. 12
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Lectures and oral presentations  (22):
  • Drug-tolerant persister cells and AXL
    (The 24th JFCR-ISCC 2019)
  • Circumvention of targeted drug tolerance in EGFR mutated lung cancer
    (第60回日本肺癌学会学術集会 2019)
  • Circumvention of targeted drug tolerance in lung cancer
    (International Symposium on Tumor Biology in Kanazawa 2019 2019)
  • Mechanisms of drug tolerant cells to osimertinib in EGFR mutated lung caner
    (2019)
  • 肺がんの治療抵抗性メカニズムの最新情報
    (第23回日本がん分子標的治療学会学術集会 2019)
more...
Education (4):
  • - 1995 The University of Tokushima
  • - 1995 The University of Tokushima Graduate School, Division of Medicine
  • - 1990 The University of Tokushima Faculty of Medicine School of Medicine
  • - 1990 The University of Tokushima Faculty of Medicine
Professional career (1):
  • - (The University of Tokushima)
Work history (23):
  • 2021/11 - 現在 Department of Respiratory Medicine, Faculty of Medicine, Institute of Medical Pharmaceutical and Health Sciences, Kanazawa University Professor and Chairman
  • 2017/04 - 現在 Kanazawa University Cancer Research Institute
  • 2018/04 - Kanazawa University Hospital
  • 2017/09 - WPI Nano Life Science Institute (LSI)(併任)
  • 2017/06 - Ministry of Education,Culture,Sports,Science and Technology
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Committee career (48):
  • 2015 - 2015 金沢大学附属病院 がん化学療法レジメン審査委員会 委員長
  • 2015 - 石川県がん対策推進連絡調整会議委員
  • 2014 - 2014 日本がん治療認定医機構教育委員会委員
  • 2013 - 2014 日本肺癌学会将来計画委員会委員
  • 2012 - 2014 日本呼吸器学会専門医制度を見直すための委員会委員
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Awards (18):
  • 2020/04 - 文部科学省 文部科学大臣表彰科学技術賞 肺がんの分子標的薬耐性を克服する研究
  • 2017/03 - 金沢大学功労賞
  • 2017/02 - 平成28年度高松宮妃癌研究基金研究助成金
  • 2014/06 - 日本がん分子標的治療学会 鶴尾隆賞
  • 2013/10 - JCA-Mauvernay Award (Applied research)(モーベルネ賞)
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Association Membership(s) (15):
International Association for the Study of Lung Cancer ,  American Association for Cancer Research ,  American Society of Clinical Oncology ,  THE JAPAN SOCIETY FOR RESPIRATORY ENDOSCOPY ,  日本臨床腫瘍学会 ,  THE JAPANESE ASSOCIATION FOR MOLECULAR TARGET THERAPY OF CANCER ,  アメリカ癌学会 ,  日本気管支学会 ,  日本肺癌学会 ,  日本癌治療学会 ,  日本癌学会 ,  日本転移学会 ,  日本リウマチ学会 ,  日本呼吸器学会 ,  日本内科学会
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