Research field (2):
Molecular biology
, Pharmaceuticals - chemistry and drug development
Research keywords (4):
遺伝子
, 酸素
, 二次代謝産物
, 生合成
Papers (70):
Kazuki Ishikawa, Makoto Hashimoto, Kunpei Komatsu, Takaaki Taguchi, Susumu Okamoto, Koji Ichinose. Characterization of stereospecific enoyl reductase ActVI-ORF2 for pyran ring formation in the actinorhodin biosynthesis of Streptomyces coelicolor A3(2). Bioorganic & Medicinal Chemistry Letters. 2022. 128727
Kazuki Ishikawa, Masaki Ishii, Takashi Yaguchi, Toshiaki Katada, Koji Ichinose, Shinya Ohata. epi-Aszonalenin B from Aspergillus novofumigatus inhibits NF-κB activity induced by ZFTA-RELA fusion protein that drives ependymoma. Biochemical and biophysical research communications. 2022. 596. 104-110
熊本卓哉, 海沼美香, 高橋梓, 松尾佳香, 片川和明, 田口貴章, 市瀬浩志. Total Synthesis of 6-Deoxydihydrokalafungin, a Key Biosynthetic Precursor of Actinorhodin, and Its Epimer. Molecules. 2021. 26. 21. 6397-6397
Xiaofeng Cai, Caiyun Li, Koji Ichinose, Yali Jiang, Ming Liu, Huili Wang, Caixia Gong, Le Li, Juan Wan, Yiming Zhao, et al. A single-domain small protein Med-ORF10 regulates the production of antitumour agent medermycin in Streptomyces. Microbial Biotechnology. 2021. 14. 5. 1918-1930
Kazuki Ishikawa, Shinya Ohata, Masaki Ishii, Takashi Yaguchi, Toshiaki Katada, Koji Ichinose. Exploratory research of bioactive compounds from fungi Aspergillus species to address unmet medcal needs. The 11th JSP-CSP-KSP Joint Symposium on Pharmacognosy (Tokyo). 2021. P3-26
Identification and Characterization of Bifunctional Enzymes Involved in Actinorhodin Biosynthesis
(61st Sympsium on the Chemistry of Natural Products 2019)
Deoxygenation in the biosynthesis of aromatic polyketides
(32nd Symposium on the Chemistry of Natural Products 1990)
Education (3):
1988 - 1991 The University of Tokyo Division of Pharmaceutical Sciences
1986 - 1988 The University of Tokyo Division of Pharmaceutical Sciences
1982 - 1986 The University of Tokyo
Professional career (3):
Ph.D. in Pharmaceutical Sciences (The University of Tokyo)
薬学修士 (東京大学大学院)
薬学博士 (東京大学大学院)
Work history (11):
2018/04 - 現在 Musashino University Research Institute of Pharmaceutical Sciences Director
2009/04 - 現在 Musashino University Graduate School of Pharmaceutical Sciences Professor
2004/04 - 現在 Musashino University Faculty of Pharmacy
2004/04 - 現在 Musashino University Chemical Laboratory of Medicinal Natural Products, Research Institute of Pharmaceutical Sciences Professor
2004/04 - 現在 Musashino University Faculty of Pharmaceutical Sciences Professor
2004/04 - 2007/03 The University of Tokyo Faculty of Pharmaceutical Sciences Lecturer (part-time)
1997/04 - 2004/03 The University of Tokyo Graduate School of Pharmaceutical Sciences Assitant Professor
1996/03 - 1997/03 The University of Tokyo Faculty of Pharmaceutical Sciences Research Associate
1993/11 - 1996/02 John Innes Centre (UK) Department of Genetics Post-Doctoral Researcher
1991/05 - 1993/09 University of Cambridge Department of Chemstry Post-doctoral Researcher
1991/04 - Special researcher of the Japan Society for the Promotion of Science Post-doctoral Researcher
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Committee career (7):
2021/01 - 現在 Ministry of Health, Labour and Welfare, Committee on Guidance-Mandatory Drugs and Non-prescription Drugs Pharmaceutical Affairs and Food Sanitation Council
2012/04 - 現在 Pharmaceuticals and Medical Devices Agency (PMDA) JP Expert Committee on Crude Drugs (B)
2009/10 - 現在 Japanese Society of Pharmacognosy Public Relations Committee
2009/10 - 現在 日本生薬学会 理事(広報委員長)
2015/04 - 2022/03 Japanese Society of Pharmacognosy International Symposium Committee
2015/04 - 2022/03 日本生薬学会 理事(国際シンポジウム対応委員会委員長)
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Awards (1):
2003/06 - 日本放線菌学会浜田賞(研究奨励賞)受賞
Association Membership(s) (4):
JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY
, SOCIETY FOR ACTINOMYCETES JAPAN
, THE PHARMACEUTICAL SOCIETY OF JAPAN
, THE JAPANESE SOCIETY OF PHARMACOGNOSY