2008 - 2010 Functional analysis of the enzymes involved in the structural modification of polyketides and its application to the production of novel scaffolds
2005 - 2007 Production of novel biologically active molecules based on the functional analysis of glycosylation enzymes related to secondary metabolism
2003 - 2003 ゲノム研究基軸放線菌における抗生物質生合成鍵酵素の構造予測と機能解析
2002 - 2003 Functional Analysis of Genes Encoding Glycosyltransferases Involved in the Biosynthesis of Deoxysugar-containing Antibiotics
2002 - 2002 ゲノム研究基軸放線菌における抗生物質生合成遺伝子機能の網羅的解析
2000 - 2002 Functional Analysis of Biosynthetic Enzymes for Natural Products
2001 - 2001 ゲノム研究基軸放線菌における抗生物質生合成遺伝子機能の網羅的解析
2000 - 2000 ゲノム研究基軸放線菌における抗生物質生合成遺伝子機能の網羅的解析
1999 - 2000 ステロイドサポニンの生合成機構解明を基軸とする薬用遺伝子資源の探索と利用
1997 - 1998 放射菌ポリケタイド系配糖体抗生物質の合理的分子設計とその生産
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Papers (80)：
Masaki Ishii, Tsuyoshi Yamada, Kazuki Ishikawa, Koji Ichinose, Michel Monod, Shinya Ohata. The Ptk2-Pma1 pathway enhances tolerance to terbinafine in Trichophyton rubrum. Antimicrobial agents and chemotherapy. 2024. e0160923
Koji Ichinose. An intrenational Symposium in the Japanese Society of Pharmacognosy. The Japanese Journal of Pharmacognosy. 2024. 78. 1. 31-38
Makoto Hashimoto, Susumu Watari, Takaaki Taguchi, Kazuki Ishikawa, Takuya Kumamoto, Susumu Okamoto, Koji Ichinose. Actinorhodin Biosynthesis Terminates with an Unprecedented Biaryl Coupling Reaction. Angewandte Chemie (International ed. in English). 2023. 62. 5. e202214400
Kazuki Ishikawa, Makoto Hashimoto, Kunpei Komatsu, Takaaki Taguchi, Susumu Okamoto, Koji Ichinose. Characterization of stereospecific enoyl reductase ActVI-ORF2 for pyran ring formation in the actinorhodin biosynthesis of Streptomyces coelicolor A3(2). Bioorganic & Medicinal Chemistry Letters. 2022. 66. 128727-128727
Kazuki Ishikawa, Masaki Ishii, Takashi Yaguchi, Toshiaki Katada, Koji Ichinose, Shinya Ohata. epi-Aszonalenin B from Aspergillus novofumigatus inhibits NF-κB activity induced by ZFTA-RELA fusion protein that drives ependymoma. Biochemical and biophysical research communications. 2022. 596. 104-110
Shinya Ohata, Kazuki Ishikawa, Masaki Ishii, Takashi Yaguchi, Koji Ichinose. Exploration of fungal metabolites that inhibit carcinogenic NF-κB signaling and elucidation of their mechanism of action. The 144th Annual Meeting of the Pharmaceutical Society of Japan. 2024. 31P-am086
Kazuki Ishikawa, Nao Kamiya, Shinya Ohata, Masaki Ishii, Takashi Yaguchi, Koji Ichinose. Search for NF-κB signaling inhibitors by fungal secondary metabolites to overcome unmet medical needs. The 144th Annual Meeting of the Pharmaceutical Society of Japan. 2024. 30-am089
Mizuha Yabuzaki, Makoto Hashinoto, Sarina Shimazu, Kazuki Ishikawa, Koji Ichinose. Functional analysis of Med-5, a lactonizing enzyme present in the Medermycin biosynthesis gene cluster. The 144th Annual Meeting of the Pharmaceutical Society of Japan. 2024. 29P-om070S
Sarina Shimazu, Makoto Hashimoto, Kazuki Ishikawa, Koji Ichinose. Functional Analysis of ActVI-4, an oxidoreducatse Involved in Actinorhoodin Biosynthesis (The 2nd Report). The 144th Annual Meeting of the Pharmaceutical Society of Japan. 2024. 29-pm069S
Momoka Ebara, Makoto Hashimoto, Yuta Shinmi, Yuka Kamezawa, Kazuki Ishikawa, Koji Ichinose. Functional analysis of Gra-18, a lactonizing enzyme involved in granaticin biosynthesis. The 144th Annual Meeting of the Pharmaceutical Society of Japan. 2024. 29-pm068S
Overview and Future Prospects of Pharmacy Education in Japan
(Future Education for Pharmacist in the Points of Researcher, Industrial and Academic View (Kyungpook National University, Korea) 2023)
Functional analysis of natural product biosynthetic enzymes based on homology modeling
(MOE Forum 2022 2022)
Identification and Characterization of Bifunctional Enzymes Involved in Actinorhodin Biosynthesis
(61st Sympsium on the Chemistry of Natural Products 2019)
Metabolic engineering to produce novel product systems: an example of deoxysugar biosyntehtic enzymes from actinomycetes
(121st Annual Meeting of Phamarmaceutical Society of Japan 2001)
A Genetic Approach to Understand Mechanisms and Regulation of the Biosynthesis of Benzoisochromanequinone Antibiotics
(42nd Symposium on the Chemistry of Natural Products 43(P-3) 2000)
1988 - 1991 The University of Tokyo Graduate School of Pharmaceutical Sciences Division of Pharmaceutical Sciences
1986 - 1988 The University of Tokyo Graduate School of Pharmaceutical Sciences Division of Pharmaceutical Sciences
1982 - 1986 The University of Tokyo Faculty of Pharmaceutical Science
Professional career (3)：
BSc (The University of Tokyo)
MSc (The University of Tokyo)
PhD (The University of Tokyo)
Work history (12)：
2023/04 - 現在 Musashino University Graduate School of Pharmaceutical Sciences Dean
2023/04 - 現在 Musashino University Faculty of Pharmacy Dean
2009/04 - 現在 Musashino University Graduate School of Pharmaceutical Sciences Professor
2004/04 - 現在 Musashino University Chemical Laboratory of Medicinal Natural Products, Research Institute of Pharmaceutical Sciences Professor
2004/04 - 現在 Musashino University Faculty of Pharmaceutical Sciences Professor
2018/04 - 2023/03 Musashino University Research Institute of Pharmaceutical Sciences Director
2004/04 - 2007/03 The University of Tokyo Faculty of Pharmaceutical Sciences Lecturer (part-time)
1997/04 - 2004/03 The University of Tokyo Graduate School of Pharmaceutical Sciences Assitant Professor
1996/03 - 1997/03 The University of Tokyo Faculty of Pharmaceutical Sciences Research Associate
1993/11 - 1996/02 John Innes Centre (UK) Department of Genetics Post-Doctoral Researcher
1991/05 - 1993/09 University of Cambridge Department of Chemstry Post-doctoral Researcher
1991/04 - Special researcher of the Japan Society for the Promotion of Science Post-doctoral Researcher
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Committee career (14)：
2024/03 - 現在 The Japanese Society of Pharmacognosy Vice President
2022/06 - 現在 公益財団法人 薬理研究会 評議員
2021/01 - 現在 The Pharmaceutical Society of Japan delegate
2021/01 - 現在 Ministry of Health, Labour and Welfare, Committee on Guidance-Mandatory Drugs and Non-prescription Drugs Pharmaceutical Affairs and Food Sanitation Council
2012/04 - 現在 Pharmaceuticals and Medical Devices Agency (PMDA) JP Expert Committee on Crude Drugs (B)
2009/10 - 現在 Japanese Society of Pharmacognosy Public Relations Committee
2009/10 - 2024/03 一般社団法人 日本生薬学会 理事(広報委員長)
2015/04 - 2022/03 Japanese Society of Pharmacognosy International Symposium Committee
2015/04 - 2022/03 The Japanese Society of Pharmacognosy Head, International Symposium Committee
2012/04 - 2016/03 日本放線菌学会 理事(学術企画担当)
2008/04 - 2010/03 The Japanese Society of Pharmacognosy Finance Officer
2006/04 - 2010/03 日本放線菌学会 理事(学術企画担当)
2004/04 - 2010/03 日本放線菌学会 学術企画委員
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Awards (1)：
2003/06 - Society for Actinomycetes Japan Hamada Award Biosynthetic Studies on Model Antibiotics towards Elucidation and Utilization of Actinomycete Secondary Metabolism
Association Membership(s) (4)：
JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY
, SOCIETY FOR ACTINOMYCETES JAPAN
, THE PHARMACEUTICAL SOCIETY OF JAPAN
, THE JAPANESE SOCIETY OF PHARMACOGNOSY
