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J-GLOBAL ID：200901071072593238 Update date: Sep. 05, 2024

Mitsunaga Kanae

ミツナガカナエ | Mitsunaga Kanae

Research field (6)： Biomedical engineering , Developmental biology , Laboratory animal science , Cell biology , Molecular biology , Physiology

Research keywords (5)： CDS , 卵胞形成、卵幹細胞 , Primordial Germ cell , fluorescence-activated cell sorting , Image Cytometry

Research theme for competitive and other funds (3)：

2021 - 2024 Characterize oogonial stem cells and follicle cells with surface antigens
2017 - 2022 The creation of the de novo vector for the newly Cell Delivery System (CDS)
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Papers (15)：

Jumpei Taguchi, Hirofumi Shibata, Mio Kabata, Masaki Kato, Kei Fukuda, Akito Tanaka, Sho Ohta, Tomoyo Ukai, Kanae Mitsunaga, Yosuke Yamada, et al. DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency. Nature communications. 2021. 12. 1. 5041-5041
Yukinori Terada, Norihide Jo, Yoshiki Arakawa, Megumi Sakakura, Yosuke Yamada, Tomoyo Ukai, Mio Kabata, Kanae Mitsunaga, Yohei Mineharu, Sho Ohta, et al. Human Pluripotent Stem Cell-Derived Tumor Model Uncovers the Embryonic Stem Cell Signature as a Key Driver in Atypical Teratoid/Rhabdoid Tumor. Cell reports. 2019. 26. 10. 2608-2621
Jo N, Sogabe Y, Yamada Y, Ukai T, Kagawa H, Mitsunaga K, Woltjen K, Yamada Y. Platforms of in vivo genome editing with inducible Cas9 for advanced cancer modeling. Cancer science. 2019. 110. 3. 926-938
Takashi Ikeda, Takafusa Hikichi, Hisashi Miura, Hirofumi Shibata, Kanae Mitsunaga, Yosuke Yamada, Knut Woltjen, Kei Miyamoto, Ichiro Hiratani, Yasuhiro Yamada, et al. Srf destabilizes cellular identity by suppressing cell-type-specific gene expression programs. Nature Communications. 2018. 9. 1
Koji Kitazawa, Takafusa Hikichi, Takahiro Nakamura, Kanae Mitsunaga, Azusa Tanaka, Masahiro Nakamura, Tatsuya Yamakawa, Shiori Furukawa, Mieko Takasaka, Naoki Goshima, et al. OVOL2 Maintains the Transcriptional Program of Human Corneal Epithelium by Suppressing Epithelial-to-Mesenchymal Transition. CELL REPORTS. 2016. 15. 6. 1359-1368

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MISC (8)：

林拓也, 若尾昌平, 光永佳奈枝, 北田正章, 合瀬恭幸, 渡部浩司, 松瀬大, 繁本妙子, 尾上浩隆, 田畑泰彦, et al. パーキンソン病モデル霊長類動物における骨髄間質幹細胞由来A9ドーパミン神経細胞自家移植. JSMI Report. 2012. 5. 2. 45
光永佳奈枝. 造血幹細胞数の制御機構の解明. 自治医科大学紀要. 2011. 33. 195-196
HIRAOKA Nobuya, KIKUCHI Jiro, NOBUYOSHI Masaharu, WADA Taeko, MITSUNAGA Kanae, KANO Yasuhlko, FURUKAWA Yusuke. Bendamustine induces G2 cell cycle arrest and apoptosis in lymphoid malignancies. 臨床血液. 2010. 51. 9. 995
菊池次郎, 和田妙子, 清水瑠美, 和泉透, 光永佳奈枝, 畑野かおる, 信吉正治, 小澤敬也, 加納康彦, 古川雄祐. ボルテゾミブの抗骨髄腫作用はヒストン脱アセチル化酵素発現の抑制を介する. 臨床血液. 2009. 50. 9. 931
光永佳奈枝, 阿部訓也, 荒木喜美, 山村研一, 諸橋憲一郎, 水崎博文, Giguere Vincent, 中潟直己. 卵胞発育の基礎から臨床へ核内オーファンレセプター ERR-β遺伝子の始原生殖細胞発生過程における発現・機能解析. 日本不妊学会雑誌. 2005. 50. 4. 286-287

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Education (2)：

2000 - 2004 Kumamoto University Medicine nstitute of Molecular Embryology and Genetics, Division of Developmental Genetics
1998 - 2000 Kumamoto University Science Institute of Molecular Embryology and Genetics, Division of Developmental Genetics

Work history (6)：

2012/06 - 2023/03 Kyoto University CiRA Assistant Professor
2010/10 - 2012/06 Tohoku University Graduate School of Medicine Department of Stem Cell Biology and Histology & Department of Anatomy and Anthropology, Research scientist
2011/03 - 2012/05 RIKEN Center for Molecular Imaging Science Functional Probe Research Laboratory Visiting scientist
2008/10 - 2010/09 Jichi Medical University School of Medicine Division of Stem Cell Regulation, Center for Molecular Medicine Assistant Professor,
2005/04 - 2008/09 National Institute of Advanced Industrial Science and Technology Glycoscience Post-doctoral Fellow

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Association Membership(s) (5)：

Japanese Society for Immunology(JSI) , the Japan Cytometry Society , Japan Society for Reproductive Medicine , JAPANESE SOCIETY of DEVELOPMENTAL BIOLOGISTS , The Molecular Biology Society of Japan

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