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Rchr

J-GLOBAL ID：200901072173430867 Update date: Sep. 19, 2024

Nakaki Toshio

Nakaki Toshio | Nakaki Toshio

Affiliation and department：
Homepage URL (1)： http://www.med.teikyo-u.ac.jp/~nakaki/nakaki.html

Research field (2)： Pharmacology , Neuroscience - general

Research keywords (6)： Development of therapeutics for neurodegerative diseases , 応用薬理学・医療系薬学 , 神経化学・神経薬理学 , Applied Pharmacology and Medical Pharamacology , Neurochemistry and Neuropharmacology , Nitric Oxide

Research theme for competitive and other funds (27)：

2015 - 2018 micro RNA as the master key for protection of oxidative stress
2012 - 2016 A study on mice with hypoglycemia and high cognitive ability
2009 - 2011 A study on CNS oxidative stress-resistant mouse
2005 - 2006 Effect of an alpha-lb adrenoceptor antagonist on methamphetamine-induced neuronal toxicity
2002 - 2003 Rotenone-Induced Parkinsonism

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Papers (212)：

Nobuko Matsumura, Chisato Kinoshita, Wattanaporn Bhadhprasit, Toshio Nakaki, Koji Aoyama. A purine derivative, paraxanthine, promotes cysteine uptake for glutathione synthesis. Journal of pharmacological sciences. 2023. 151. 1. 37-45
Chisato Kinoshita, Kazue Kikuchi-Utsumi, Koji Aoyama, Ryo Suzuki, Yayoi Okamoto, Nobuko Matsumura, Daiki Omata, Kazuo Maruyama, Toshio Nakaki. Inhibition of miR-96-5p in the mouse brain increases glutathione levels by altering NOVA1 expression. Communications biology. 2021. 4. 1. 182-182
Matsumura Nobuko, Kinoshita Chisato, Nakaki Toshio, Aoyama Koji. The development of miR-96-5p gene knock out technique by CRISPR/Cas9 system. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2021. 94. 0. 3-P1-37
Kinoshita Chisato, Matsumura Nobuko, Aoyama Koji, Nakaki Toshio. Increased glutathione via NOVA1 by administration of an inhibitor of the microRNA miR-96-5p. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2021. 94. 0. 1-P1-34
Chisato Kinoshita, Yayoi Okamoto, Koji Aoyama, Toshio Nakaki. MicroRNA: A Key Player for the Interplay of Circadian Rhythm Abnormalities, Sleep Disorders and Neurodegenerative Diseases. Clocks & sleep. 2020. 2. 3. 282-307

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MISC (119)：

木下千智, 中木敏夫, 青山晃治. 日内リズムを呈するmicroRNAによる神経グルタチオンの制御メカニズム. 日本分子生物学会年会プログラム・要旨集(Web). 2019. 42nd
Matsumura Nobuko, Aoyama Koji, Nakaki Toshio. Structure-dependent action of caffeine derivatives on cysteine uptake in mouse hippocampus slice. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2017. 133. 3. S175-S175
Kikuchi-Utsumi Kazue, Matsumura Nobuko, Watabe Masahiko, Nakaki Toshio. Effect of nitric oxide synthase inhibitor on methamphetamine-induced dopaminergic neurotoxicity in rats. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2016. 130. 3. S232-S232
Matsumura Nobuko, Aoyama Koji, Nakaki Toshio. Effects of caffeine metabolites on the ability of cysteine uptake in brain slice. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2016. 130. 3. S193-S193
Matsumura Nobuko, Nakaki Toshio. The mechanism-dependent effect of the drug combination derived from the isobolographic analysis of the anticonvulsant. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2015. 128. 3. S252-S252

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Patents (5)：

Mir 96-5p inhibitor and a screening method for the inhibitor
miR-96-5p阻害剤とそのスクリーニング法
グルタチオン増加物質のスクリーニング方法
試験問題提供・復習システム、試験問題提供システム、復習システム、サーバー、試験問題の提供方法、及び復習方法
SCREENING METHOD OF GLUTATHIONE-INCREASING SUBSTANCE

Books (11)：

Side _Effects of Drugs Annual, 40th Edition
Elsevier 2018
Side Effects of Drugs Annual, 39th Edition
Elsevier 2017
Side Effects of Drugs Annual, 38th Edition
Elsevier 2016
Side Effects of Drugs Annual, 37th Edition
2015
Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease
Academic Press 2014