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J-GLOBAL ID:200901073518187975   Update date: Mar. 25, 2025

Sugimoto Hiroshi

スギモト ヒロシ | Sugimoto Hiroshi
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Affiliation and department:
Other affiliations (1):
Homepage URL  (1): http://www.riken.jp/biometal/index.htm
Research field  (3): Biophysics ,  Structural biochemistry ,  Molecular biochemistry
Research keywords  (4): トランスポーター ,  結晶構造解析 ,  ヘム ,  X線
Research theme for competitive and other funds  (23):
  • 2024 - 2027 新しい動的構造解析法の開発とABCトランスポーターへの応用
  • 2023 - 2026 EPR・X線による深海および南極海微生物由来酵素の高活性・高安定性機構の解明
  • 2021 - 2024 病原菌ヘムトランスポーターの構造変化の追跡と基質輸送機構の解明
  • 2019 - 2024 Protein metalation that controls biometal dynamics in the cells
  • 2020 - 2022 Structure of reactive oxygen species generated by heme-enzyme
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Papers (109):
  • Satoshi Nagao, Wako Kuwano, Takehiko Tosha, Keitaro Yamashita, Joshua Kyle Stanfield, Chie Kasai, Shinya Ariyasu, Kunio Hirata, Go Ueno, Hironori Murakami, et al. XFEL crystallography reveals catalytic cycle dynamics during non-native substrate oxidation by cytochrome P450BM3. Communications Chemistry. 2025
  • Rachel Bolton, Moritz M Machelett, Jack Stubbs, Danny Axford, Nicolas Caramello, Lucrezia Catapano, Martin Malý, Matthew J Rodrigues, Charlotte Cordery, Graham J Tizzard, et al. A redox switch allows binding of Fe(II) and Fe(III) ions in the cyanobacterial iron-binding protein FutA from Prochlorococcus. Proceedings of the National Academy of Sciences of the United States of America. 2024. 121. 12. e2308478121
  • Hiroaki Inaba, Yuma Shisaka, Shinya Ariyasu, Erika Sakakibara, Garyo Ueda, Yuichiro Aiba, Nobutaka Shimizu, Hiroshi Sugimoto, Osami Shoji. Heme-substituted protein assembly bridged by synthetic porphyrin: achieving controlled configuration while maintaining rotational freedom. RSC Advances. 2024. 14. 13. 8829-8836
  • Joshua Kyle Stanfield, Hiroki Onoda, Shinya Ariyasu, Chie Kasai, Eleanor Mary Burfoot, Hiroshi Sugimoto, Osami Shoji. Investigating the applicability of the CYP102A1-decoy-molecule system to other members of the CYP102A subfamily. Journal of Inorganic Biochemistry. 2023. 245. 112235-112235
  • Shinya Ariyasu, Kai Yonemura, Chie Kasai, Yuichiro Aiba, Hiroki Onoda, Yuma Shisaka, Hiroshi Sugimoto, Takehiko Tosha, Minoru Kubo, Takashi Kamachi, et al. Catalytic Oxidation of Methane by Wild-Type Cytochrome P450BM3 with Chemically Evolved Decoy Molecules. ACS Catalysis. 2023. 8613-8623
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MISC (116):
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Education (3):
  • 1997 - 2000 Hokkaido University
  • 1995 - 1997 Hokkaido University
  • 1991 - 1995 北海道大学 理学部・高分子学科
Professional career (1):
  • 博士(理学) (北海道大学)
Work history (7):
  • 2018/04 - 現在 RIKEN
  • 2017/04 - 現在 University of Hyogo of Life Science, Graduate School
  • 2017/04 - RIKEN
  • 2009/04 - RIKEN
  • 2005/09 - RIKEN
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Association Membership(s) (6):
日本生物物理学会 ,  日本結晶学会 ,  日本化学会 ,  日本放射光学会 ,  日本蛋白質科学会 ,  日本生化学会
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