Rchr
J-GLOBAL ID：200901074259609269   Update date: May. 21, 2024

Izawa Takashi

イザワ タカシ | Izawa Takashi
Affiliation and department：
Okayama University Department of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences

About Okayama University Department of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences


Job title： Associate Professor
Homepage URL  (2)： https://nrid.nii.ac.jp/ja/nrid/1000030380017/ ,  https://nrid.nii.ac.jp/en/nrid/1000030380017/
Research field  (1)： Developmental dentistry
Research keywords  (7)： Rare Disease ,  Rheumatoid Arthritis ,  coupling factor ,  osteoclast ,  Orthodontics ,  骨免疫学 ,  Osteoimmunology
Research theme for competitive and other funds  (28)：
  • 2022 - 2026 Mechanism of epigenetic regulation about bone remodeling in the ortho gnathic congenital diseases
  • 2022 - 2025 Filamin A mediated epithelial-mesenchymal transition during embryonic palate development
  • 2022 - 2025 Analysis of dysregulated bone healing mechanisms via aryl hydrocarbon receptor by smoking and its regulation
  • 2021 - 2024 Challenge to analyze the regulatory mechanism of palatal wound healing via dioxin receptor by smoking
  • 2021 - 2022 Analysis of bone destruction mechanisms via RANKL and AhR signal crosstalk in osteoclasts
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Papers (57)：
  • Habumugisha J, Nakamura M, Kono K, Uchida K, Konko M, Izawa T, Kamioka H. Novel prediction models for pharyngeal-airway volume based on the cranial-base and midsagittal cross-sectional area of the airway in the pharyngeal region: a cephalometric and magnetic resonance imaging study. Orthodontics and Craniofacial Research. 2023. 27. 3. 394-402
  • 中西 泰之, 植田 紘貴, 星島 光博, 井澤 俊, 上岡 寛. NSAIDs系鎮痛薬の常用による歯の移動の遅延を認めた上下顎前突症例の一治験例. 日本矯正歯科学会大会プログラム・抄録集. 2022. 81回. 229-229
  • Islamy Rahma Hutami, Takashi Izawa, Tsendsuren Khurel-Ochir, Takuma Sakamaki, Akihiko Iwasa, Shuhei Tomita, Eiji Tanaka. HIF-1α controls palatal wound healing by regulating macrophage motility via S1P/S1P 1 signaling axis. Oral Diseases. 2022. 28. 4. 1157-1169
  • Wei Zou, Takashi Izawa, Nidhi Rohatgi, Steven Y Zou, Yongjia Li, Steven L Teitelbaum. ThPOK inhibits osteoclast formation via NFATc1 transcription and function. JBMR Plus. 2022. 6. 4. e10613
  • 坂巻 拓馬, 岩浅 亮彦, Xia Linze, 井澤 俊, 加納 史也, 山本 朗仁, 田中 栄二. 低出力超音波パルス照射は機械的負荷に起因して生じた下顎頭軟骨変性を修復する. 日本顎関節学会雑誌. 2021. 33. Suppl. 80-80
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MISC (23)：
  • Yusaku Hamada, Takashi Izawa, Yuri Yoshikawa, Gohji Kozaki, Hiroshi Kamioka. Mechanisms of osteoclast differentiation and fracture healing mediated by IGFBP signaling. Journal of Japanese Society for Bone Morphometry. 2023. 33. 2. 48-49
  • Yuri Yoshikawa, Takashi Izawa, Yusaku Hamada, Gohji Kozaki, Yuki Namba, Hiroshi Kamioka. Analysis of osteoclast differentiation and bone healing mechanism via aryl hydrocarbon receptor. Journal of Japanese Society for Bone Morphometry. 2023. 33. 2. 46-47
  • Takashi Izawa. Crosstalk between RANKL and AhR signaling regulates TMJ-RA. 2023. 38. 68-73
  • 井澤 俊, 吉川 友理, 浜田 勇作, 上岡 寛. 内分泌撹乱物質AhRリガンドB[a]PはCyp1a1シグナルを介して破骨細胞分化および骨代謝を制御する. 第41回日本骨形態計測学会記録集 特別企画〜医用画像から新しい骨形態計測への橋渡しを担うAI〜. 2022. 78-79
  • IZAWA Takashi. Analysis of molecular mechanism about epigenetic gene related to osteoclast differentiation and treatment strategy for osteoporosis. Sumitomo electronic group. 2019. 15-20
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Lectures and oral presentations  (80)：
  • AhR ligands regulates subchondral bone remodeling via osteoclast differentiation
    (2024 Bones and Teeth Gordon Research Conference 2024)
  • Roles for B[a]P and FICZ in subchondral bone metabolism and experimental temporomandibular joint osteoarthritis via the AhR/Cyp1a1 signaling axis.
    (The 46th Annual Meeting of the Molecular Biology Society of Japan 2023)
  • Mechanisms of osteoclast differentiation and fracture healing mediated by IGF binding ptotein
    (The 82nd Annual Meeting of the Japanese Orthodontic Society 2023)
  • Effects of urothelial cancer-associated 1 (UCA1) long non-coding RNA on osteoclast differentiation and function
    (The 82nd Annual Meeting of the Japanese Orthodontic Society 2023)
  • Regulatory mechanism of mandibular condylar resorption via AhR and RANKL signaling in the field of osteoimmune network.
    (The 82nd Annual Meeting of the Japanese Orthodontic Society 2023)
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Works (5)：
  • 内分泌撹乱物質AhRリガンドであるB[a]PおよびFICZはAhR/Cyp1a1シグナル伝達経路を介して破骨細胞分化および骨代謝を制御する
    日本骨代謝学会 first author記事 吉川友理, 井澤俊, 上岡寛 2021 - 現在
  • The nuclear receptor AhR controls bone homeostasis by regulating osteoclast differentiation via the RANK/c-Fos signaling axis.
    JSBMR, first author, Izawa Takashi 2017 -
  • Rebamipide Attenuates Mandibular Condylar Degeneration in a Murine Model of TMJ-OA by Mediating a Chondroprotective Effect and by Downregulating RANKL-mediated Osteoclastogenesis.
    JSBMR, first author, Izawa Takashi
  • Smad3 Deficiency Leads to Mandibular Condyle Degradation via the Sphingosine 1-Phosphate (S1P)/S1P3 Signaling Axis.
    JSBMR, first author, Izawa Takashi
  • ASXL2 Regulates Glucose, Lipid, and Skeletal Homeostasis.
    JSBMR, first author, Izawa Takashi
Education (2)：
  • - 2004 The University of Tokushima
  • - 2000 The University of Tokushima Faculty of Dentistry School of Dentistry
Professional career (1)：
  • Ph.D. (The University of Tokushima)
Work history (6)：
  • 2021/09 - 現在 Okayama University Department of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Associate Professor
  • 2019/10 - 2021/08 Okayama University Hospital, Orthodontics lecturer
  • 2015/04 - 2019/09 Tokushima University Graduate School, Institute of Biomedical Sciences Department of Orthodontics and Dentofacial Orthopedics Assistant Professor
  • 2012/10 - 2015/03 University of Tokushima Graduate School, Institute for Health Bioscience Department of Orthodontics and Dentofacial Orthopedics Assistant Professor
  • 2009/10 - 2012/09 Washington University in St. Louis, School of Medicine Department of Pathology and Immunology Postdoc Research Associate
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Committee career (12)：
  • 2024/01 - 現在 Chu-Shikoku Orthodontic Society Sub President
  • 2022/04 - 現在 日本矯正歯科学会 代議員
  • 2022/01 - 現在 Chu-shikoku orthodontic society Council
  • 2021/08 - 現在 岡山歯学会 評議員
  • 2021/11 - 2022/03 令和3年度岡山大学未来懇談会参加メンバー
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Awards (34)：
  • 2023/07 - Japanese Society for Bone Morphometry Plenary award
  • 2023/06 - Japanese Society for Bone Morphometry plenary young investigator ward
  • 2023/05 - Japanese Stomatological Society rising scientist award
  • 2023/02 - Plenary presentation award
  • 2022/10 - JOS plenary investigator award
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Association Membership(s) (16)：
Japanese Society for Bone Morphometry ,  Okayama Dental Society ,  日本矯正歯科学会 ,  Shikoku Dental Research Association ,  JAPANESE STOMATOLOGICAL SOCIETY ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  JAPANESE ASSOCIATION FOR ORAL BIOLOGY ,  AMERICAN SOCIETY FOR BONE AND MINERAL RESEARCH ,  JAPANESE SOCIETY FOR BONE AND MINERAL RESEARCH ,  日本口蓋裂学会 ,  日本顎変形症学会 ,  日本免疫学会 ,  中・四国矯正歯科学会 ,  日本顎関節学会 ,  Japanese Society for Immunology ,  Japanese Orthodontic Society
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