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J-GLOBAL ID：200901074428422149 Update date: Jun. 30, 2024

Kawanami Yasuhiro

カワナミヤスヒロ | Kawanami Yasuhiro

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Affiliation and department：
Job title： Professor emeritus

Research field (2)： Bioorganic chemistry , Synthetic organic chemistry

Research keywords (2)：有機化学 , Organic Chemistry

Research theme for competitive and other funds (8)：

2019 - 2022 Structure–activity study and analysis of mechanism of action of vibsanins focused on pro-/anti-inflammatory switching
2010 - 2013 希少糖エステルライブラリーからの新規な抗線虫薬の探索
2010 - 2013 希少糖誘導体の合成と生理活性研究
1995 - 2008 希少糖脂肪酸エステルの酵素的合成
1998 - 1998 遷移金属元素とゲルマニウム元素の協同作業を利用する新触媒反応の精密設計

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Papers (49)：

Ryo C Yanagita, Yoshiyuki Suzuki, Yasuhiro Kawanami, Yusuke Hanaki, Kazuhiro Irie. Effect of phenolic-hydroxy-group incorporation on the biological activity of a simplified aplysiatoxin analog with an (R)-(-)-carvone-based core. Bioscience, Biotechnology, and Biochemistry. 2024
Tomoki Sekido, Kosuke Yamamoto, Ryo C. Yanagita, Yasuhiro Kawanami, Yusuke Hanaki, Kazuhiro Irie. A simplified analog of debromoaplysiatoxin lacking the B-ring of spiroketal moiety retains protein kinase C-binding and antiproliferative activities. 2022. 23. 116988
Yoshiyuki Suzuki, Keiichi Moritoki, Mizuki Kajiwara, Ryo C Yanagita, Yasuhiro Kawanami, Yusuke Hanaki, Kazuhiro Irie. Design, synthesis, and biological activity of a synthetically accessible analog of aplysiatoxin with an (R)-(-)-carvone-based conformation-controlling unit. Bioscience, Biotechnology, and Biochemistry. 2022
Ryo C. Yanagita, Mao Otani, Satoshi Hatanaka, Hiroto Nishi, Shota Miyake, Yusuke Hanaki, Masashi Sato, Yasuhiro Kawanami, Kazuhiro Irie. Analysis of binding mode of vibsanin A with protein kinase C C1 domains: An experimental and molecular dynamics simulation study. Journal of Molecular Structure. 2022. 132866-132866
Hironobu Ishiyama, Ryo C. Yanagita, Kazune Takemoto, Natsumi Kitaguchi, Yuuki Uezato, Yasunori Sugiyama, Masashi Sato, Yasuhiro Kawanami. Evaluation of the Anti-Proliferative Activity of Rare Aldohexoses against MOLT-4F and DU-145 Human Cancer Cell Line and Structure-Activity Relationship of D-Idose. Journal of Applied Glycoscience. 2020. 67. 3. 95-101

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MISC (25)：

FURUTA, Yoshiaki, FUKADA, Kazuhiro, AFACH, Ghanwa, KAWANAMI, Yasuhiro. Study on Surface Activity of Sugar-based Surfactants: Surface Tension Measurements for Aqueous Solutions of Sugar Fatty Acid Esters. Proceedings of the Third Symposium of International Society of Rare Sugars II. 2008. 249-253
Yasuhiro Kawanami, Ghanwa Afach, Kazuhiro Fukada, Ken Izumori. Enzymatic Production of D-Psicose Fatty Acid Diesters and their emulsification Power. Proceedings of the Third Symposium of International Society of RareSugars II. 2008. 63-68
Yasuhiro Kawanami, Ghanwa Afach, Hisashi Kato-Noguchi, Ken Izumori. Enzymatic Production of D-Allose Fatty Acid Esters and its Biological Activity on Plant Growth. Proceedings of the Third Symposium of International Society of Rare Sugars. 2008. 69-74
FURUTA, Yoshiaki, FUKADA, Kazuhiro, AFACH, Ghanwa, KAWANAMI, Yasuhiro. Study on Surface Activity of Sugar-based Surfactants: Surface Tension Measurements for Aqueous Solutions of Sugar Fatty Acid Esters. Proceedings of the Third Symposium of International Society of Rare Sugars II. 2008. 249-253
Yasuhiro Kawanami, Ghanwa Afach, Kazuhiro Fukada, Ken Izumori. Enzymatic Production of D-Psicose Fatty Acid Diesters and their emulsification Power. Proceedings of the Third Symposium of International Society of RareSugars II. 2008. 63-68

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Patents (10)：

グリセロ糖脂質の製造方法及びそれに用いる微生物
黄色色素の製造方法
不斉還元触媒、その溶液、その調整方法並びにそれを用いた光学活性アルコール類の製造方法
新規な希少糖脂肪酸エステルおよびその製造方法
Method for Catalytic Asymmetric Dihydroxylation of Olefins Using Heterocyclic Chiral Ligands

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Lectures and oral presentations (166)：

新規希少糖誘導体Allulofuranosyl allopyranosideの合成
(日本農芸化学会中四国支部第64講演会 2023)
Azulene型vibsanin誘導体の合成と生物活性評価
(日本農芸化学会中四国支部第64講演会 2023)
B環を除去したAplysiatoxin単純化アナログの合成と生物活性
(日本農芸化学会2022年度大会 2022)
(R)-(-)-Carvoneを用いるAplysiatoxin単純化アナログの合成と活性評価
(日本農芸化学会2022年度大会 2022)
B環を除去したAplysiatoxin単純化アナログの合成研究
(日本農芸化学会中四国支部第64講演会 2021)

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Works (3)：

新規CBS系触媒の合成研究
2006 -
新規CBS系触媒の開発研究
2005 -
オキサザボロリジン系不斉還元触媒の合成研究
2004 -

Education (5)：

1990 - 1991 マサチューセッツ工科大学化学科 K. B. Sharpless 研究室
1983 - 1984 ミズリー・コロンビア大学化学科
1980 - 1983 九州大学大学院理学研究科博士課程化学専攻
1978 - 1980 九州大学大学院理学研究科修士課程化学専攻
1974 - 1978 Kyushu University School of Sciences Department of Chemistry

Professional career (1)：

Doctor of Science (Kyushu University)

Work history (16)：

2021/04 - 現在香川大学農学部客員研究員(ケミカルバイオロジー)
2021/04 - 現在香川大学農学部非常勤講師(有機化学)
2020/04 - 2021/03 Kagawa University library
2016/04 - 2021/03 Kagawa University International Instutute of Rare Sugar Research and Education
2003/10 - 2021/03 Ehime University The United Graduate School of Agricultural Sciences

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Committee career (15)：

2019/04 - 2021/03 日本化学会中国四国支部地区幹事
2012/04 - 2021/03 日本農芸化学会中国四国支部参与
1993/04 - 2020/03 The Society of Synthetic Organic Chemistry, Japan secretary
2015/12 - 2017/11 有機合成化学協会代議員
2016/03 - 2017/02 日本化学会中国四国支部副支部長

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Awards (1)：

1998/11 - 有機合成化学協会中国四国支部奨励賞

Association Membership(s) (4)：

日本農芸化学会 , The Society of Synthetic Organic Chenistry , The Chemical Society of Japan , アメリカ化学会

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