Rchr
J-GLOBAL ID:200901075527241829
Update date: Jan. 30, 2024
Yasui Kohichiroh
ヤスイ コウイチロウ | Yasui Kohichiroh
Affiliation and department:
Research field (1):
Gastroenterology
Research theme for competitive and other funds (11):
- 2021 - 2024 キネシン分子モーターを構成するKAP3の異常が胃印環細胞癌の発生に関与する機序
- 2015 - 2018 Analysis of DNA methylation and microRNA expression in hepatocellular carcinoma
- 2012 - 2015 Analysis of dysregulated lipid and iron metabolisms in patients with nonalcoholic fatty liver disease
- 2011 - 2013 Alteration of polarity protein PAR-3 in esophageal squamous cell carcinoma
- 2008 - 2010 Analysis of newly recognized amplified region in 1q21p in hepatocellular carcinoma
- 2008 - 2010 ERK5 is a target for gene amplification at 17p11 and promotes cell growth in hepatocellular carcinoma by regulating mitotic entry.
- 2006 - 2007 Identification of molecular target genes for therapy in hepatocellular carcinoma.
- 2005 - 2006 Alteration in Copy-Numbers of Genes as a Mechanism for Acquired Drug Resistance
- 2003 - 2004 A target gene, SKP2, within the 5p13 amplicon that is frequently detected in cancers.
- 2000 - 2004 がんの新規ゲノム異常の探索と多項目遺伝情報によるがんの個性診断法の開発
- 2001 - 2002 Identification of target genes within an amplicon at 14ql2-21 in esophageal squamous cell carcinoma
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Papers (133):
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曽田 智大, 岩井 直人, 玄 泰行, 安居 幸一郎. 胃印環細胞癌において、KAP3発現低下は細胞間接着を低下させ、ラミニン輸送を障害する。(Loss of KAP3 reduces intercellular adhesion and impairs transport of laminin in gastric signet ring cell carcinoma.). 日本癌学会総会記事. 2022. 81回. P-2250
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Tomohiro Soda, Yasuyuki Gen, Kei Terasaki, Naoto Iwai, Tomoko Kitaichi, Osamu Dohi, Hiroyoshi Taketani, Yuya Seko, Atsushi Umemura, Taichiro Nishikawa, et al. Loss of KAP3 decreases intercellular adhesion and impairs intracellular transport of laminin in signet ring cell carcinoma of the stomach. Scientific reports. 2022. 12. 1. 5050-5050
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Kei Terasaki, Yasuyuki Gen, Naoto Iwai, Tomohiro Soda, Tomoko Kitaichi, Osamu Dohi, Hiroyoshi Taketani, Yuya Seko, Atsushi Umemura, Taichiro Nishikawa, et al. SOX2 enhances cell survival and induces resistance to apoptosis under serum starvation conditions through the AKT/GSK-3β signaling pathway in esophageal squamous cell carcinoma. Oncology letters. 2021. 21. 4. 269-269
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Hirayuki Enomoto, Yoshiyuki Ueno, Yoichi Hiasa, Hiroki Nishikawa, Shuhei Hige, Yasuhiro Takikawa, Makiko Taniai, Toru Ishikawa, Kohichiroh Yasui, Akinobu Takaki, et al. The transition in the etiologies of hepatocellular carcinoma-complicated liver cirrhosis in a nationwide survey of Japan. Journal of gastroenterology. 2020. 56. 2. 158-167
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Shinya Okishio, Kanji Yamaguchi, Hiroshi Ishiba, Nozomi Tochiki, Kota Yano, Aya Takahashi, Seita Kataoka, Keiichiroh Okuda, Yuya Seko, Yu Liu, et al. PPARα agonist and metformin co-treatment ameliorates NASH in mice induced by a choline-deficient, amino acid-defined diet with 45% fat. Scientific reports. 2020. 10. 1. 19578-19578
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MISC (40):
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Masatoshi Kudo, Kazuomi Ueshima, Masafumi Ikeda, Takuji Torimura, Hiroshi Aikata, Namiki Izumi, Takahiro Yamasaki, Keisuke Hino, Teiji Kuzuya, Norio Isoda, et al. TACTICS: Final overall survival (OS) data from a randomized, open label, multicenter, phase II trial of transcatheter arterial chemoembolization (TACE) therapy in combination with sorafenib as compared with TACE alone in patients (pts) with hepatocellular carcinoma (HCC). JOURNAL OF CLINICAL ONCOLOGY. 2021. 39. 3
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Masatoshi Kudo, Kazuomi Ueshima, Takuji Torimura, Nobukazu Tanabe, Masafumi Ikeda, Hiroshi Aikata, Namiki Izumi, Takahiro Yamasaki, Shunsuke Nojiri, Keisuke Hino, et al. Randomized, open label, multicenter, phase II trial of transcatheter arterial chemoembolization (TACE) therapy in combination with sorafenib as compared with TACE alone in patients with hepatocellular carcinoma: TACTICS trial. JOURNAL OF CLINICAL ONCOLOGY. 2018. 36. 15
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瀬古 裕也, 西川 太一朗, 楳村 敦詩, 山口 寛二, 森口 理久, 安居 幸一郎, 木村 真由美, 飯島 宏明, 橋本 敏夫, 角田 圭雄, et al. NASH合併2型糖尿病患者におけるカナグリフロジン投与後の肝機能への影響の検討. 糖尿病. 2018. 61. Suppl.1. S-160
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Masatoshi Kudo, Kazuomi Ueshima, Masafumi Ikeda, Takuji Torimura, Nobukazu Tanabe, Hiroshi Aikata, Namiki Izumi, Takahiro Yamasaki, Shunsuke Nojiri, Keisuke Hino, et al. Randomized, open label, multicenter, phase II trial comparing transarterial chemoembolization (TACE) plus sorafenib with TACE alone in patients with hepatocellular carcinoma (HCC): TACTICS trial. JOURNAL OF CLINICAL ONCOLOGY. 2018. 36. 4
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石破博, 新井正弘, 川端利博, 瀬古裕也, 楳村敦詩, 西川太一朗, 山口寛二, 森口理久, 安居幸一郎, 伊藤義人. 非アルコール性脂肪肝における非侵襲的線維化スコアで評価された肝線維化と動脈硬化の関係. 肝臓. 2017. 58. Supplement 3. A865-A865
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Education (2):
- 1991 - 1995 Kyoto Prefectural University of Medicine
- 1982 - 1988 Kyoto Prefectural University of Medicine
Professional career (1):
Work history (3):
- 2018/04 - 現在 Bukkyo University
- 2003/04 - 2018/03 Kyoto Prefectural University of Medicine
- 2000/05 - 2003/03 Tokyo Medical and Dental University
Awards (2):
- 2016 - 日本肝臓学会 欧文機関誌『Hepatology Research』High Citation賞
- 2011 - 日本消化器病学会 日本消化器病学会奨励賞
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