Akiba Satoshi

アキバサトシ | Akiba Satoshi

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www.kyoto-phu.ac.jp/labo/byoutai/byoutai-j.html

Research field (4)： Metabolism and endocrinology , Pathobiochemistry , Pharmacology , Pharmaceuticals - health and biochemistry

Research keywords (9)：非アルコール生脂肪肝炎 , 粥状動脈硬化症 , ホスホリパーゼA<sub>2</sub> , 炎症 , メタボリックシンドローム , phospholipase A2 , non-alcoholic fatty liver disease , atherosclerosis , metabolic syndrome

Research theme for competitive and other funds (12)：

2023 - 2026 Roles of group IVA phospholipase A2 in hepatic fibrosis in high-fat diet-fed mice after returning to a normal diet
2020 - 2023 Inhibition of liver fibrosis by cell type-specific deficiency of group IVA PLA2 as a novel therapeutic strategy for NASH
2017 - 2020 Inhibition of group IVA phospholipase A2 as a therapeutic strategy for non-alcoholic steatohepatitis
2014 - 2017 Involvement of group IVA phospholipase A2 in the development and progression of non-alcoholic steatohepatitis
2008 - 2011 Mechanisms for the development of atherosclerosis with low HDL levels and of fatty liver

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Papers (56)：

KEIICHI ISHIHARA, RYUTO SAKODA, MASAKO MIZOGUCHI, MITSUGU FUJITA, CHIAMI MOYAMA, YURI OKUTANI, KAZUYUKI TAKATA, MIWA TANAKA, TAKASHI MINAMI, HARUHIKO SAGO, et al. Suppression ofSleeping Beauty-induced Gliomagenicity in Ts1Cje Mice, a Model of Down Syndrome. Anticancer Research. 2024. 44. 2. 489-495
Aina Fukuda, Souichi Nakashima, Yoshimi Oda, Kaneyasu Nishimura, Hidekazu Kawashima, Hiroyuki Kimura, Takashi Ohgita, Eri Kawashita, Keiichi Ishihara, Aoi Hanaki, et al. Plantainoside B in Bacopa monniera binds to Aβ aggregates attenuating neuronal damage and memory deficits induced by Aβ. Biol. Pharm. Bull. 2023. 46. 2. 320-333
Keiichi Ishihara, Eri Kawashita, Satoshi Akiba. Bio-Metal Dyshomeostasis-Associated Acceleration of Aging and Cognitive Decline in Down Syndrome. Biological & pharmaceutical bulletin. 2023. 46. 9. 1169-1175
Takeyoshi Ozaki, Eri Kawashita, Keiichi Ishihara, Satoshi Akiba. Deficiency of Group IVA Phospholipase A2 in Collagen-Producing Cells Alleviates the Aggravated Hepatic Fibrosis in High-Fat Diet-Fed Mice after Returning to a Normal Diet. Biological & pharmaceutical bulletin. 2023. 46. 3. 488-493
Eri Kawashita, Takeyoshi Ozaki, Keiichi Ishihara, Chihiro Kashiwada, Satoshi Akiba. Endothelial group IVA phospholipase A2 promotes hepatic fibrosis with sinusoidal capillarization in the early stage of non-alcoholic steatohepatitis in mice. Life Sciences. 2022. 294. 120355-120355

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MISC (80)：

三崎友菜, 河下映里, 西村周泰, 石原慶一, 野口鈴華, 高田和幸, 松尾理, 秋葉聡. Examination of the involvement of α2-antiplasmin in survival and maturation of transplanted neural progenitor cells. 日本薬学会年会要旨集(Web). 2023. 143rd
西村美紅, 河下映里, 永井信夫, 石原慶一, 井上和奏, 宮崎優奈, 松尾理, 秋葉聡. Involvement of α2-antiplasmin in neurogenesis after cerebral infarction. 日本薬学会年会要旨集(Web). 2023. 143rd
福田愛菜, 中嶋聡一, 中嶋聡一, 尾田好美, 尾田好美, 西村周泰, 西村周泰, 河嶋秀和, 木村寛之, 扇田隆司, et al. Detection of Aβ aggregates and neuroprotection by plantainoside B, an Aβ-binding compound from Bacopa monniera. 日本薬学会年会要旨集(Web). 2023. 143rd
千代華歩, 河下映里, 秋葉聡, 山川和弘, 石原慶一. Correlation between brain copper accumulation and emotional memory impairment in mouse models of Down syndrome. 日本薬学会年会要旨集(Web). 2023. 143rd
神保里菜, 高田修治, 斉藤美知子, 山川和弘, 河下映里, 左合治彦, 秋葉聡, 石原慶一. Narrowing down the genetic loci responsible for copper accumulation in the Down syndrome brain. 日本薬学会年会要旨集(Web). 2023. 143rd

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Books (6)：

分子病態薬物治療学第3版 : 生化・生理・薬理的視点にたった疾患へのアプローチ
京都廣川書店 2024 ISBN:9784910844275
分子病態薬物治療学第2版 : 生化・生理・薬理的視点にたった疾患へのアプローチ
京都廣川書店 2020 ISBN:9784909197634
分子病態薬物治療学 : 生化・生理・薬理的視点にたった疾患へのアプローチ
京都廣川書店 2017 ISBN:9784909197061
疾病と病態生理
南江堂 2016 ISBN:9784524403271
基礎から学ぶ内分泌薬学
エルゼビア・ジャパン 2013 ISBN:9784860342852

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Education (2)：

1986 - 1991 Kyoto Pharmaceutical University Graduate School of Pharmaceutical Sciences
1982 - 1986 Kyoto Pharmaceutical University Pharmaceutical Sciences Pharmaceutical Chemistry

Professional career (1)：

Doctor of Pharmaceutical Science

Work history (4)：

2008/04 - 現在 Kyoto Pharmaceutical University
1999 - 2007 Kyoto Pharmaceutical University
1998 - 1999 Kyoto Pharmaceutical University
1991 - 1998 Kyoto Pharmaceutical University

Awards (1)：

2003 - 平成14年度日本薬学会近畿支部奨励賞

Association Membership(s) (6)：

日本肝臓学会 , 日本薬学教育学会 , 日本脂質生化学会 , 日本動脈硬化学会 , 日本薬学会 , 日本生化学会

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