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J-GLOBAL ID：200901076557878917 Update date: Apr. 09, 2025

Naoki Sakai

サカイナオキ | Naoki Sakai

Affiliation and department：
Job title： Senior scientist

Research field (1)： Structural biochemistry

Research keywords (2)： Structural biochemistry , Macromolecule crystallography

Papers (55)：

K.V. Dileep, Naoki Sakai, Kentaro Ihara, Akiko Nakata, Akihiro Ito, Divya M. Sivaraman, Chi Wai Yip, Jay W. Shin, Minoru Yoshida, Mikako Shirouzu, et al. Identification of benzimidazole-6-carboxamide based inhibitors of secretory glutaminyl cyclase for the treatment of Alzheimer's disease. International Journal of Biological Macromolecules. 2025
Rina Aoki, Eri Kumagawa, Kazuaki Kamata, Hideo Ago, Naoki Sakai, Tomohisa Hasunuma, Naoaki Taoka, Yukari Ohta, Shingo Kobayashi. Engineering of acyl ligase domain in non-ribosomal peptide synthetases to change fatty acid moieties of lipopeptides. Communications Chemistry. 2025
Daniel Erlanson, Stephen Burley, James Fraser, Daren Fearon, Dale Kreitler, Maria Cristina Nonato, Naoki Sakai, Jan Wollenhaupt, Manfred S Weiss. Where to House Big Data on Small Fragments?. 2025
Kohei Takeshita, Naoki Sakai, Go Ueno, Midori Horie, Hirofumi Tsujino, Mitsuhiro Arisawa, Masaki Yamamoto, Masayoshi Arai, Taku Yamashita. A large pocket structure surrounding the catalytic center in the BCG protein fromMycobacterium tuberculosis. 2024
Toshiyuki Waki, Riki Imaizumi, Kaichi Uno, Yamato Doi, Misato Tsunashima, Sayumi Yamada, Ryo Mameda, Shun Nakata, Taro Yanai, Kohei Takeshita, et al. Structural insights into catalytic promiscuity of chalcone synthase from Glycine max (L.) Merr.: Coenzyme A-induced alteration of product specificity. Biochemical and Biophysical Research Communications. 2024. 150080-150080

MISC (7)：

Education (2)：

Professional career (1)：

Master's degree (Hokkaido University, Mar. 2000), Doctor's degree (Hokkaido University, Mar. 2003) (Hokkaido University)

Work history (11)：

2025/04 - 現在 Japan Synchrotron Radiation Research Institute Diffraction and Scattering Division Senior scientist
2023/04 - 2025/03 Japan Synchrotron Radiation Research Institute Structural Biology Division Senior scientist
2022/04 - 2023/03 Japan Synchrotron Radiation Research Institute Structural Biology Division Research Scientist
2018/10 - 2022/03 RIKEN RIKEN SPring-8 Center Research Scientist
2018/04 - 2018/09 RIKEN Center for Biosystems Dynamics Research Research scientist

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Association Membership(s) (3)：

The Crystallographic Society of Japan , The Japanese Society for Synchrotron Radiation Research , Protein Science Society of Japan

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