Rchr
J-GLOBAL ID:200901076700535139
Update date: Apr. 09, 2025 Takano Shigetsugu
タカノ シゲツグ | Takano Shigetsugu
Affiliation and department: Research field (2):
Tumor biology
, Digestive surgery
Research theme for competitive and other funds (27): - 2023 - 2026 肝内胆管癌病態形成におけるメカノトランスダクションの役割
- 2023 - 2026 ポリコームタンパクYAF2による大腸癌の進展、転移、再発における制御機構の解明
- 2023 - 2026 C5-C5aR1/2 axisを標的とした膵癌進展機構の解明と新規補体免疫賦活化療法への応用
- 2022 - 2025 大腸癌におけるRYBP を介した腫瘍制御機構の解明
- 2020 - 2023 NETsを介した膵臓癌EMT-MET plasticity機構の解明
- 2020 - 2023 膵癌進展進展機構に関わるC4BPA-CD40 axisの機能解析および治療開発
- 2019 - 2022 The elucidation of mechanism underlying pancreatic cancer progression by complement and secreted proteins in tumor microenvironment.
- 2019 - 2022 Plasticity of cancer-initiating and cancer cells in intrahepatic cholangiocarcinoma and regulation of the cancer stromal microenvironment
- 2019 - 2022 Mechanism of cancer progression mediated by IL-32-Gankyrin axis in intrahepatic cholangiocarcinoma
- 2018 - 2021 Development of precision medicine for pancreatic cancer combining near infrared imaging and biological information
- 2017 - 2020 Identification of biomarkers for biliary tract cancer by proteomic approaches
- 2016 - 2019 Elucidation of the role of KLF5, 17 in metastatic cascade of gastrointestinal cancer
- 2016 - 2019 Role of YAP/TAZ in induction of cancer-initiating cells in cholangiocarcinoma and development of new targeting therapy
- 2016 - 2019 Expression of annexin II and stromal tenascin C promotes epithelial to mesenchymal transition and correlates with distant metastasis in pancreatic cancer
- 2015 - 2018 Elucidation of molecular mechanism for pancreato-biliary cancer progression through EMT plasticity
- 2015 - 2018 New criteria of pancreatic neuroendocrine tumors depending on expression levels of transcription factors related to neural and endocrine cell development
- 2014 - 2017 Identification of novel biomarkers for pancreato-biliary cancer by comprehensive protein profiling analysis
- 2012 - 2015 Identification of drug resistance-related proteins in pancreatic cancer by SILAC quantitative proteomic approach.
- 2010 - 2012 Clinical heterogeneity brought about by tumor-initiating cells in primary liver cancer and the development of new therapeutic strategy by regulating microRNAs.
- 2009 - 2011 Interacti on between mesenchymal and cancer stem cells in pancreatic cancer
- 2009 - 2011 Increased circulating cell signaling phosphoproteins in sera are useful for early detection and the tailor-made therapy for pancreatic and biliary duct cancer patients.
- 2008 - 2010 Evaluation of immune cell functions in patients with postoperative complications using proteome and metabolome analysis.
- 2008 - 2010 Functional analysis and clinical application for ApoC-1 in patients with pancreatic cancer
- 2008 - 2010 The personalized therapy using Annexin II as a gemcitabine-resistant factor for pancreatic cancer patients after surgery.
- 2007 - 2008 Mechanismsoftheinteractionbetweencancercells andmesenchymal Cells in gastroirltestinal cancer.
- 2006 - 2007 Identification of specific pancreatic serum protein marker for early diagnosis by using ProteinChip technology
- 2006 - 2007 Proteomicsによる胆道・膵癌新規抗癌剤耐性因子の解明と臨床応用の可能性
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Papers (391): -
Kei Naito, Takanori Konishi, Tsukasa Takayashiki, Shigetsugu Takano, Daisuke Suzuki, Nozomu Sakai, Isamu Hosokawa, Takashi Mishima, Hitoe Nishino, Kensuke Suzuki, et al. Laparoscopic Cholecystectomy for a Patient after Percutaneous Endoscopic Gastrostomy due to Myotonic Dystrophy: A Case Report and Literature Review. Surgical case reports. 2025. 11. 1
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Yusuke Kouchi, Nozomu Sakai, Sakurako Harada-Kagitani, Ryotaro Eto, Takashi Mishima, Shigetsugu Takano, Katsuhiro Nasu, Jun-ichiro Ikeda, Masayuki Ohtsuka, Takashi Kishimoto. SMARCB1-deficient malignant neoplasm of the pancreas with heterogeneous morphologies that cannot be classified into existing histologic types. Pathology International. 2024
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Masaharu Ishida, Tsutomu Fujii, Masashi Kishiwada, Kazuto Shibuya, Sohei Satoi, Makoto Ueno, Kohei Nakata, Shigetsugu Takano, Katsunori Uchida, Nobuyuki Ohike, et al. Japanese classification of pancreatic carcinoma by the Japan Pancreas Society: Eighth edition. Journal of Hepato-Biliary-Pancreatic Sciences. 2024
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西野 仁惠, 高屋敷 吏, 高野 重紹, 鈴木 大亮, 酒井 望, 細川 勇, 三島 敬, 小西 孝宜, 鈴木 謙介, 仲田 真一郎, et al. 日本内視鏡外科学会技術認定合格のための集中講座 膵臓編(第3回) 腹腔鏡下尾側膵切除術(脾合併切除)(3). 消化器外科. 2024. 47. 10. 1217-1232
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Takanori Konishi, Shigetsugu Takano, Tsukasa Takayashiki, Daisuke Suzuki, Nozomu Sakai, Isamu Hosokawa, Takashi Mishima, Hitoe Nishino, Kensuke Suzuki, Shinichiro Nakada, et al. Preoperative Prediction of Long-Term Survival After Surgery in Patients with Resectable Pancreatic Ductal Adenocarcinoma. Annals of surgical oncology. 2024
more... MISC (843): -
高野 重紹, 小西 孝宜, 高屋敷 吏, 鈴木 大亮, 酒井 望, 細川 勇, 三島 敬, 西野 仁恵, 鈴木 謙介, 仲田 真一郎, et al. Liver,Pancreas,Biliary Tract Cancer 肝・胆・膵癌 肝胆膵癌におけるPrecision Medicineの展開 膵癌におけるPrecision Medicineの展開. 癌と化学療法. 2024. 51. 10. 996-1001
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高屋敷 吏, 高野 重紹, 大塚 将之. 進行胆道癌に対する集学的治療の現状と展望 胆道癌外科切除困難例および再発例に対する集学的治療戦略. 胆道. 2024. 38. 3. 300-300
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百武 佳晃, 高屋敷 吏, 高野 重紹, 鈴木 大亮, 酒井 望, 細川 勇, 三島 敬, 小西 孝宜, 西野 仁惠, 鈴木 謙介, et al. 残存予定肝に対する術前胆道ドレナージによる減黄効率の再考. 胆道. 2024. 38. 3. 460-460
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小西 孝宜, 高屋敷 吏, 大塚 将之, 高野 重紹, 鈴木 大亮, 酒井 望, 細川 勇, 三島 敬, 鈴木 謙介, 西野 仁恵, et al. 胆道癌に対するがんゲノムプロファイリング検査の現状と検査時期の重要性. 胆道. 2024. 38. 3. 465-465
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船津 悠也, 細川 勇, 酒井 望, 西野 仁惠, 高屋敷 吏, 高野 重紹, 鈴木 大亮, 三島 敬, 小西 孝宜, 鈴木 謙介, et al. 腎癌胆嚢転移の2切除例. 胆道. 2024. 38. 3. 656-656
more... Patents (4): Education (2): - 2003 - 2007 Chiba University
- - 1997 Chiba University School of Medicine
Professional career (1): Return to Previous Page