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J-GLOBAL ID：200901077359625740   Update date: Apr. 16, 2025

Adachi Yoshiyuki

アダチ ヨシユキ | Adachi Yoshiyuki
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Affiliation and department：
Tokyo University of Pharmacy and Life Sciences School of Pharmacy School of Pharmacy

About Tokyo University of Pharmacy and Life Sciences School of Pharmacy School of Pharmacy


Homepage URL  (1)： https://www.ps.toyaku.ac.jp/menekigaku/
Research field  (2)： Pharmacology ,  Pharmaceuticals - health and biochemistry
Research keywords  (4)： β-glucan ,  Allergy ,  免疫薬理学 ,  Immunopharmacology
Research theme for competitive and other funds  (16)：
  • 2024 - 2027 Analysis of expression of immunomodulatory activity associated with morphological changes in innate immune system receptor molecules
  • 2023 - 2027 Structural profiling of fungal cell wall polysaccharides using functionally modified glycoside hydrolase
  • 2021 - 2026 Application of drug discovery based on immunoreceptor-mediated regulation of osteoclastogenesis by glucan
  • 2021 - 2024 スギ花粉β-グルカンの免疫学的緒活性とアレルギー疾患との関連性に関する研究
  • 2018 - 2021 スギ花粉多糖成分によるアジュバント活性の解析
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Papers (237)：
  • Takashi Kanno, Masaki Kawasaki, Rui Tada, Toyokazu Nakasone, Shigemi Okamatsu, Kazuhiro Tamura, Hiroaki Miyaoka, Yoshiyuki Adachi. Anti-allergic Effects of Dietary Cordyceps militaris (Ryukyu-kaso) Derived from Eri Silkworm. International Journal of Medicinal Mushrooms. 2025
  • Takashi Kanno, Rui Tada, Toyokazu Nakasone, Shigemi Okamatsu, Yoichiro Iwakura, Kazuhiro Tamura, Hiroaki Miyaoka, Yoshiyuki Adachi. Heat Treatment Abolishes Cytotoxicity of the Caterpillar Medicinal Mushroom Cordyceps militaris (Ascomycota) Cold-Phosphate-Buffered Saline Extract. International Journal of Medicinal Mushrooms. 2025
  • Wataru Ariyoshi, Ayaka Koga, Yuki Kodama, Ryota Yamasaki, Yoshie Nagai-Yoshioka, Michihiko Usui, Shinichi Mochizuki, Yoshiyuki Adachi. Inhibition of osteoclast differentiation by (1→3)-β-D-glucan from Alcaligenes faecalis (curdlan) and dectin-1 interaction via the syk proteolytic system. Carbohydrate Polymer Technologies and Applications. 2025
  • Takashi Kanno, Rui Tada, Toyokazu Nakasone, Shigemi Okamatsu, Yoichiro Iwakura, Kazuhiro Tamura, Hiroaki Miyaoka, Yoshiyuki Adachi. Dectin-1-Dependent Activation of Flt3 Ligand-Induced Dendritic Cells by the Caterpillar Medicinal Mushroom Cordyceps militaris (Ascomycetes) Fruiting Body. International journal of medicinal mushrooms. 2025. 27. 6. 13-22
  • Ayaka Koga, Yoshie Nagai-Yoshioka, Ryota Yamasaki, Yoshiyuki Adachi, Wataru Fujii, Wataru Ariyoshi. Molecular Mechanisms of Curdlan-Induced Suppression of NFATc1 Expression in Osteoclasts. Journal of Cellular Biochemistry. 2025
ｍore...
MISC (267)：
  • 菅野峻史, 平塚理恵, 安達禎之. 花粉β-1,3-D-glucanの構造及び免疫活性の裸子植物花粉間比較. アレルギー. 2024. 73. 6/7
  • 山中大輔, 安達禎之. Functional modification of glycoside hydrolases for detection of fungal cell wall polysaccharides. 日本薬学会年会要旨集(Web). 2023. 143rd
  • 菅野峻史, 山口明莉, 平塚理恵, 岩倉洋一郎, 山中大輔, 安達禎之. Comparison of various pollen species in Dectin-1 dependent immune activation. 日本生体防御学会学術総会講演抄録集. 2022. 33rd
  • 山中大輔, 栗田涼香, 菅野峻史, 安達禎之. Development of novel structure-specific detection method for β-1,3/1,6-glucan using split-NanoLuc-fused β-glucan binding proteins. 日本薬学会年会要旨集(Web). 2022. 142nd
  • 滝田峻也, 菅野峻史, 山中大輔, 安達禎之. Comparison of mouse strains in the reactivity to β-1,3-D-glucan in Cryptomeria japonica pollen. 日本薬学会年会要旨集(Web). 2022. 142nd
ｍore...
Patents (6)：
  • β-1,3-1,6-グルカンの測定方法
  • β-グルカン結合タンパク質、β-グルカン検出キット、人工DNAおよび細菌
  • アルペルギルス由来グルカン
  • 細胞表面抗原CD14を認識する新規なモノクローナル抗体
  • 抗デクチン-1モノクローナル抗体を産生するハイブリドーマ
ｍore...
Books (4)：
  • 新しい微生物学
    廣川書店 2016 ISBN:9784567520577
  • 免疫学概説
    廣川書店 2010 ISBN:9784567534222
  • 内因性敗血症モデルにおける肝不全発症機構の解析
    [大野尚仁] 2006
  • 抗腫瘍性(1→3)-β-D-グルカン及びその誘導体の構造と免疫学的諸活性との相関性に関する研究
    [安達禎之] 1990
Professional career (1)：
  • (BLANK)
Association Membership(s) (14)：
European Academy of Allergy and Clinical Immunology ,  Japanese Society of Allergology ,  Japanese Society for Bacteriology ,  国際エンドトキシン自然免疫学会(International Endotoxin and Innate Immunity Society) ,  日本エンドトキシン研究会 ,  日本医真菌学会 ,  米国免疫学会(AMERICAN ASSOCIATION of IMMUNOLOGIST) ,  日本生体防御学会 ,  日本生化学会 ,  日本糖質学会 ,  日本農芸化学会 ,  日本癌学会 ,  日本免疫学会 ,  日本薬学会
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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