Niwa Hitoshi

ニワヒトシ | Niwa Hitoshi

Affiliation and department：
Job title： Professor

Research field (1)： Developmental biology

Research theme for competitive and other funds (16)：

2019 - 2024 クロマチン複製における転写因子ネットワークの継承機構の解析
2017 - 2020 Investigation of molecular mechanism governing open chromatin formation in mouse ES cells
2009 - 2015 Behavioral analyses of genes and cells in early mammalian development
2002 - 2007 幹細胞の可塑性と未分化性維持機構
2004 - 2006 How are the cells on the surface of embryoid body derived from ES cells induced to differentiate into primitive endoderm?

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Papers (137)：

Ryuki Shimada, Yuzuru Kato, Naoki Takeda, Sayoko Fujimura, Kei-ichiro Yasunaga, Shingo Usuki, Hitoshi Niwa, Kimi Araki, Kei-ichiro Ishiguro. STRA8-RB interaction is required for timely entry of meiosis in mouse female germ cells. Nature Communications. 2023. 14. 1
Lusubilo Mwalilino, Mariko Yamane, Kei-ichiro Ishiguro, Shingo Usuki, Mitsuhiro Endoh, Hitoshi Niwa. The role of Zfp352 in the regulation of transient expression of 2-cell specific genes in mouse embryonic stem cells. Genes to Cells. 2023
Hiroko Sano, Akira Nakamura, Mariko Yamane, Hitoshi Niwa, Takashi Nishimura, Kimi Araki, Kazumasa Takemoto, Kei-ichiro Ishiguro, Hiroki Aoki, Yuzuru Kato, et al. The polyol pathway is an evolutionarily conserved system for sensing glucose uptake. PLOS Biology. 2022. 20. 6. e3001678-e3001678
Yuki Horisawa-Takada, Chisato Kodera, Kazumasa Takemoto, Akihiko Sakashita, Kenichi Horisawa, Ryo Maeda, Ryuki Shimada, Shingo Usuki, Sayoko Fujimura, Naoki Tani, et al. Meiosis-specific ZFP541 repressor complex promotes developmental progression of meiotic prophase towards completion during mouse spermatogenesis. Nature Communications. 2021. 12. 1
Hidekazu Naganuma, Koichiro Miike, Tomoko Ohmori, Shunsuke Tanigawa, Takumi Ichikawa, Mariko Yamane, Masatoshi Eto, Hitoshi Niwa, Akio Kobayashi, Ryuichi Nishinakamura. Molecular detection of maturation stages in the developing kidney. Developmental biology. 2021. 470. 62-73

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MISC (55)：

高田幸, 小寺千聡, 竹本一政, 前田亮, 坂下陽彦, 坂下陽彦, 松浦公美, 丹羽仁史, 立花誠, 行川賢, et al. 生殖細胞特異的ジンクフィンガータンパク質は減数分裂前期パキテン脱出の転写制御に働く. 日本分子生物学会年会プログラム・要旨集(Web). 2019. 42nd
Hiroki Ura, Hitoshi Niwa, Kuniya Abe. The role of DNA methylation. in Epigenetic barrier between Naive and Primed state. GENES & GENETIC SYSTEMS. 2015. 90. 6. 390-390
丹羽仁史. THE COMMENTARY 再生医療の基盤となる転写因子ネットワークに関する基礎知識. 再生医療 : 日本再生医療学会雑誌. 2014. 13. 2. 150-154
Graziano Martello, Toshimi Sugimoto, Evangelia Diamanti, Anagha Joshi, Rebecca Hannah, Satoshi Ohtsuka, Berthold Goettgens, Hitoshi Niwa, Austin Smith. Esrrb Is a Pivotal Target of the Gsk3/Tcf3 Axis Regulating Embryonic Stem Cell Self-Renewal. CELL STEM CELL. 2013. 12. 5. 630-630
丹羽仁史. 2012年ノーベル生理学・医学賞成体細胞が多能性に初期化されうることの発見 (2012年ノーベル賞はiPS細胞に). 現代化学. 2012. 501. 24-27

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Professional career (1)：

Work history (2)：

2015 - Kumamoto University Institute of Molecular Embryology and Genetics
2015 - Professor, ,Institute of Molecular Embryology and Genetics,Kumamoto University

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