Rchr
J-GLOBAL ID：200901078319425974
Update date: Jan. 30, 2024
Niwa Hitoshi
ニワ ヒトシ | Niwa Hitoshi
Affiliation and department：
Job title：
Professor
Research field (1)：
Developmental biology
Research theme for competitive and other funds (16)：
- 2019 - 2024 クロマチン複製における転写因子ネットワークの継承機構の解析
- 2017 - 2020 Investigation of molecular mechanism governing open chromatin formation in mouse ES cells
- 2009 - 2015 Behavioral analyses of genes and cells in early mammalian development
- 2002 - 2007 幹細胞の可塑性と未分化性維持機構
- 2004 - 2006 How are the cells on the surface of embryoid body derived from ES cells induced to differentiate into primitive endoderm?
- 2002 - 2006 転写制御から見た体細胞初期化機構の解析
- 2000 - 2004 形態的分節と上皮化誘導
- 2002 - 2003 Oct-3/4とCdx-2による栄養外胚葉分化制御機構の解析
- 2002 - 2002 ES細胞を用いた未分化細胞が分化する過程の網羅的解析
- 2000 - 2001 インスレーターの発生工学への応用
- 1999 - 2001 ESTABLISHMENT OF FEEDER- AND SERUM-FREE CULTURE SYSTEM OF ES CELLS AND ITS APPLICATION TO PROPAGATE ES CELLS FROM INBRED MICE EMBRYOS
- 2000 - 2000 Oct-3/4による初期分化決定機構の解析
- 1999 - 1999 Oct-3/4による初期分化決定機構の解析
- 1997 - 1998 染色体外発現ベクター系を用いた胚幹細胞の分化を規定する遺伝子の検索
- 1992 - 1994 PRODUCTION OF MOUSE MODELS FOR MALFORMATION BY GENE TRAP
- 1992 - 1994 Production of mouse models for human diseases by gene targeting
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Papers (135)：
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Ryuki Shimada, Yuzuru Kato, Naoki Takeda, Sayoko Fujimura, Kei-ichiro Yasunaga, Shingo Usuki, Hitoshi Niwa, Kimi Araki, Kei-ichiro Ishiguro. STRA8-RB interaction is required for timely entry of meiosis in mouse female germ cells. Nature Communications. 2023. 14. 1
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Lusubilo Mwalilino, Mariko Yamane, Kei-ichiro Ishiguro, Shingo Usuki, Mitsuhiro Endoh, Hitoshi Niwa. The role of Zfp352 in the regulation of transient expression of 2-cell specific genes in mouse embryonic stem cells. Genes to Cells. 2023
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Hiroko Sano, Akira Nakamura, Mariko Yamane, Hitoshi Niwa, Takashi Nishimura, Kimi Araki, Kazumasa Takemoto, Kei-ichiro Ishiguro, Hiroki Aoki, Yuzuru Kato, et al. The polyol pathway is an evolutionarily conserved system for sensing glucose uptake. PLOS Biology. 2022. 20. 6. e3001678-e3001678
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Yuki Horisawa-Takada, Chisato Kodera, Kazumasa Takemoto, Akihiko Sakashita, Kenichi Horisawa, Ryo Maeda, Ryuki Shimada, Shingo Usuki, Sayoko Fujimura, Naoki Tani, et al. Meiosis-specific ZFP541 repressor complex promotes developmental progression of meiotic prophase towards completion during mouse spermatogenesis. Nature Communications. 2021. 12. 1
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Hidekazu Naganuma, Koichiro Miike, Tomoko Ohmori, Shunsuke Tanigawa, Takumi Ichikawa, Mariko Yamane, Masatoshi Eto, Hitoshi Niwa, Akio Kobayashi, Ryuichi Nishinakamura. Molecular detection of maturation stages in the developing kidney. Developmental biology. 2021. 470. 62-73
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MISC (47)：
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Hiroki Ura, Hitoshi Niwa, Kuniya Abe. The role of DNA methylation. in Epigenetic barrier between Naive and Primed state. GENES & GENETIC SYSTEMS. 2015. 90. 6. 390-390
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丹羽 仁史. THE COMMENTARY 再生医療の基盤となる転写因子ネットワークに関する基礎知識. 再生医療 : 日本再生医療学会雑誌. 2014. 13. 2. 150-154
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Graziano Martello, Toshimi Sugimoto, Evangelia Diamanti, Anagha Joshi, Rebecca Hannah, Satoshi Ohtsuka, Berthold Goettgens, Hitoshi Niwa, Austin Smith. Esrrb Is a Pivotal Target of the Gsk3/Tcf3 Axis Regulating Embryonic Stem Cell Self-Renewal. CELL STEM CELL. 2013. 12. 5. 630-630
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丹羽 仁史. 2012年ノーベル生理学・医学賞 成体細胞が多能性に初期化されうることの発見 (2012年ノーベル賞はiPS細胞に). 現代化学. 2012. 501. 24-27
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Hitoshi Niwa, Kenjiro Adachi. Rewiring of transcription factor network. DEVELOPMENTAL BIOLOGY. 2010. 344. 1. 417-417
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Professional career (1)：
Work history (2)：
- 2015 - Kumamoto University Institute of Molecular Embryology and Genetics
- 2015 - Professor, ,Institute of Molecular Embryology and Genetics,Kumamoto University
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