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J-GLOBAL ID:200901078521814389   Update date: Aug. 24, 2024

Nishizuka Makoto

ニシヅカ マコト | Nishizuka Makoto
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Affiliation and department:
Job title: Associate Professor
Homepage URL  (1): http://nature.cc.hirosaki-u.ac.jp/staff/makoto-nishizuka/
Research field  (4): Food sciences ,  Applied biochemistry ,  Pharmaceuticals - health and biochemistry ,  Nutrition and health science
Research keywords  (5): 骨粗鬆症 ,  遺伝子発現 ,  がん ,  肥満 ,  脂肪細胞
Research theme for competitive and other funds  (19):
  • 2022 - 2026 ラット初代培養肝細胞を用いた高リン刺激伝達経路の解明
  • 2017 - 2020 脂肪細胞のインスリン抵抗性惹起におけるカリウムチャネルの役割と機能の解明
  • 2018 - 新規脂肪細胞分化制御因子によるがん細胞の転移制御機構の解明
  • 2014 - 2017 新規骨分化抑制因子fad104の機能解析と骨関連疾患発症における役割の解明
  • 2017 - コーヒー成分ががん細胞の上皮間葉転換(EMT)に与える影響とその分子機構の解明
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Papers (48):
  • Naoki Nanashima, Hayato Maeda, Akira Nakajima, Makoto Nishizuka, Tsuyoshi Narumi, Junji Ichita, Koh Itoku. Apple Pomace Extract Induces Cell Proliferation and Increases Type I Collagen and Hyaluronan Production in Human Skin Fibroblasts In Vitro. Plant Foods for Human Nutrition. 2024
  • Ayumi Sasaki, Yoshifumi Yamaya, Noriyuki Notoya, Makoto Nishizuka. Cycloalliin, an Organosulfur Compound in Garlic, Inhibits EMT and Invasion of the A549 Non-Small Cell Lung Cancer Cell Line. BPB Reports. 2024. 7. 4. 101-105
  • Ryoko Yamamoto, Eriko Takahashi, Maho Harada, Izumi Sawahata, Makoto Nishizuka. Luteolin enhances oxidative stress tolerance <i>via</i> the <i>daf-16</i> pathway in the nematode <i>Caenorhabditis elegans</i>. Food Science and Technology Research. 2024. 30. 2. 253-260
  • Kotone Satoh, Satoshi Sakai, Makoto Nishizuka. Knockdown of RhoQ, a member of Rho GTPase, accelerates TGF-β-induced EMT in human lung adenocarcinoma. Biochemistry and Biophysics Reports. 2022. 32. 101346-101346
  • Misa Nozaki, Makoto Nishizuka. Repression of RhoJ expression promotes TGF-β-mediated EMT in human non-small-cell lung cancer A549cells. Biochemical and biophysical research communications. 2021. 566. 94-100
more...
MISC (22):
  • M. Goto, M. Nishizuka, S. Osada, M. Imagawa. The role of fad104, a positive regulator for adipogenesis, in TGF-beta 1-induced epithelial to mesenchymal transition. MOLECULAR BIOLOGY OF THE CELL. 2016. 27
  • M. Nishizuka, W. Horinouchi, E. Yamada, S. Osada, M. Imagawa. KCNMA1 contributes to the regulation of insulin signalling in mature adipocytes. MOLECULAR BIOLOGY OF THE CELL. 2016. 27
  • N. Ochiai, M. Nishizuka, S. Osada, M. Imagawa. The role of fad24, a positive regulator for adipogenesis, in early embryonic development and muscle cell activation. FEBS JOURNAL. 2015. 282. 286-286
  • M. Nishizuka, W. Horinouchi, E. Yamada, S. Osada, M. Imagawa. The role of KCNMA1 in mature adipocytes. FEBS JOURNAL. 2015. 282. 285-285
  • D. Katoh, M. Nishizuka, S. Osada, M. Imagawa. Fad104, a positive regulator of adipogenesis, inhibits invasion and metastasis of cancer cells through the suppression of STAT3 activity. FEBS JOURNAL. 2015. 282. 284-284
more...
Education (3):
  • 2000 - 2003 大阪大学大学院 薬学研究科 博士後期課程
  • 1998 - 2000 大阪大学大学院 薬学研究科 博士前期課程
  • 1993 - 1997 Tohoku University Faculty of Pharmaceutical Sciences
Professional career (1):
  • 大阪大学/博士(薬学)
Work history (4):
  • 2018/04 - 現在 Hirosaki University Faculty of Agriculture and Life Science
  • 2009/04 - 2018/03 Nagoya City University Medicin
  • 2007/04 - 2009/03 Nagoya City University Medicin
  • 2003/04 - 2007/03 Nagoya City University Medicin
Awards (1):
  • 2003/01 - 日本薬学会近畿支部 奨励賞
Association Membership(s) (4):
米国細胞生物学会 ,  JAPAN SOCIETY FOR THE STUDY OF OBESITY ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY
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