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J-GLOBAL ID:200901078824517034   Update date: Feb. 13, 2025

Yamamoto Akihito

ヤマモト アキヒト | Yamamoto Akihito
Clips
Affiliation and department:
Research field  (1): Medical biochemistry
Research theme for competitive and other funds  (24):
  • 2021 - 2024 Analysis of joint regeneration mechanism by secretory sialic acid recognition lectin
  • 2020 - 2023 Analysis of the mechanisms of organ formation by cell-cell and cell-extracellular communications
  • 2017 - 2020 Novel therapeutic strategies for amyotrophic lateral sclerosis using human deciduous dental pulp stem cells and their active ingredients
  • 2017 - 2020 Cell fate determination of mesenchymal stem cells by extracellular mechanical stress
  • 2017 - 2020 Development of a novel treatment method for xerostomia by dental pulp stem cell-derived humoral factor
Show all
Papers (68):
  • Cheng Ding, Noboru Hashimoto, Fumiya Kano, Hirofumi Tenshin, Takahiro Arai, Linze Xia, Yang Xu, Houjun Lao, Yifei Wang, Tomonori Iwasaki, et al. Factors secreted from the stem cells of human exfoliated deciduous teeth inhibit osteoclastogenesis through the activation of the endogenous antioxidant system. Journal of oral biosciences. 2025. 100618-100618
  • Noboru Hashimoto, Shizuka Ito, Akira Harazono, Akiko Tsuchida, Yasuhiro Mouri, Akihito Yamamoto, Tetsuya Okajima, Yuhsuke Ohmi, Keiko Furukawa, Yasusei Kudo, et al. Bidirectional signals generated by Siglec-7 and its crucial ligand tri-sialylated T to escape of cancer cells from immune surveillance. iScience. 2024. 27. 11. 111139-111139
  • Xia Linze, Kano Fumiya, Hashimoto Noboru, Liu Yao, Khurel-Ochir Tsendsuren, Ogasawara Naoko, Ding Cheng, Xu Yang, Hibi Hideharu, Iwasaki Tomonori, et al. Conditioned Medium From Stem Cells of Human Exfoliated Deciduous Teeth Alleviates Mouse Osteoarthritis by Inducing sFRP1-Expressing M2 Macrophages. Stem Cells Translational Medicine. 2024. Vol.13. No.4. 399-413
  • XIA Linze, Kano Fumiya, Hashimoto Noboru, DING Cheng, XU Yang, HIBI Hideharu, Iwasaki Tomonori, Tanaka Eiji, Yamamoto Akihito. Conditioned Medium from Stem Cells of Human Exfoliated Deciduous Teeth Partially Alters the Expression of Inflammation-associated Molecules of Mouse Condylar Chondrocytes via Secreted Frizzled-related Protein 1. Journal of Oral Health and Biosciences. 2023. Vol.35. No.2. 52-60
  • Kano Fumiya, Hashimoto Noboru, Liu Yao, Xia Linze, Nishihara Takaaki, Oki Wakana, Kawarabayashi Keita, Mizusawa Noriko, Aota Keiko, Sakai Takayoshi, et al. Therapeutic benefits of factors derived from stem cells from human exfoliated deciduous teeth for radiation-induced mouse xerostomia. Scientific Reports. 2023. Vol.13. No.1. 2706-2719
more...
MISC (58):
  • 丁程, 橋本登, 加納史也, 山本朗仁. Conditioned medium from deciduous dental pulp stem cells inhibited RANKL-induced osteoclastogenesis. 日本再生医療学会総会(Web). 2024. 23rd
  • 夏霖澤, 加納史也, 橋本登, 田中栄二, 山本朗仁. M2 Macrophages induced by MSC Alleviate Osteoarthritis via sFRP1-mediated Wnt signal inhibition. 日本再生医療学会総会(Web). 2024. 23rd
  • 徐陽, 橋本登, 加納史也, 山本朗仁. Conditioned medium from stem cells of human exfoliated deciduous teeth ameliorates atopic dermatitis. 日本再生医療学会総会(Web). 2024. 23rd
  • 山本朗仁, 橋本登, 加納史也, XIA Linze, XIA Linze, DING Cheng, 田中栄二, 高橋伸典. Development of joint regeneration drugs using sialic acid recognition lectins. Journal of Oral Biosciences Supplement (Web). 2022. 2022
  • Tanaka Eiji, LIU YAO, XIA LINZE, Ogasawara Naoko, Sakamaki Takuma, Kano Fumiya, Hashimoto Noboru, Feng Xingmei, Yamamoto Akihito. Effectiveness of low-intensity pulsed ultrasound on osteoarthritis of the temporomandibular joint: A review. Annals of Biomedical Engineering. 2020. Vol.48. No.8. 2158-2170
more...
Patents (10):
Books (4):
  • Multifaceted Neuro-Regenerative Activities of Human Dental Pulp Stem Cells for Functional Recovery after Spinal Cord Injury
    INTEC 2014
  • Multifaceted Neuro-Regenerative Activities of Human Dental Pulp Stem Cells for Functional Recovery after Spinal Cord Injury
    2014
  • 歯髄幹細胞の可能性
    朝倉書店 2012
  • 再生医療叢書・歯髄幹細胞の可能性
    朝倉書店 2012
Lectures and oral presentations  (53):
  • The therapeutic effect of soluble sialic acid-recognizing immunoglobulin-like lectin 9 on the temporomandibular joint arthritis
    (2023年度骨・筋とCaクラスター・ミニリトリート 2024)
  • Therapeutic benefits of factors derived from stem cells from human exfoliated deciduous teeth for radiation-induced mouse xerostomia
    (四国免疫フォーラム 2023)
  • Conditioned Medium from M2 Macrophages Alleviates Murine Temporomandibular Joint Osteoarthritis
    (第22回日本再生医療学会総会抄録 2023)
  • Soluble Siglec-9 attenuated the joint destruction in Collagen Antibody Induced Arthritis mouse model
    (第22回日本再生医療学会総会抄録 2023)
  • Therapeutic benefits of factors derived from stem cells from human exfoliated deciduous teeth for radiation-induced mouse xerostomia
    (第64回歯科基礎医学会学術大会 2022)
more...
Works (3):
  • 歯髄幹細胞由来の抗炎症性マクロファージ誘導因子を用いた末梢神経再生療法の開発
    2014 - 2016
  • 歯髄幹細胞の無血清培養上清(CM)を用いた劇症性肝炎および特発性間質性肺炎の治療法開発
    2013 - 2014
  • ヒト歯髄幹細胞の培養上清をもちいた中枢神経再生療法の開発
    2011 - 2012
Education (4):
  • - 1992 Nagasaki University
  • - 1992 Nagasaki University Graduate School, Division of Dental Research
  • - 1988 Nagasaki University School of Dentistry
  • - 1988 Nagasaki University Faculty of Dentistry
Work history (9):
  • 2016/11 - 現在 徳島大学大学院医歯薬学研究部 組織再生制御学 教授
  • 2010/04 - 2016/10 名古屋大学大学院医学研究科 口腔外科 准教授
  • 2008/08 - 2010/03 名古屋大学大学院医学研究科 口腔外科 特任准教授
  • 2005/04 - 2008/07 名古屋大学医学部生化学第二講座 非常勤講師
  • 2001/04 - 2008/07 RIKEN
Show all
Committee career (4):
  • 2019/04 - 現在 特定非営利活動法人 日本口腔科学会 評議委員
  • 2017/04 - 現在 社団法人 日本解剖学会 教育委員
  • 2015 - 現在 日本炎症再生医学会 評議委員
  • 2010/04 - 現在 日本再生医療学会 評議委員
Awards (3):
  • 2024/03/26 - 日本再生医療学会総会 優秀演題賞 Conditioned medium from stem cells of human exfoliated deciduous teeth ameliorates atopic dermatitis
  • 2018/02/06 - 公益財団法人康楽会 康楽賞 幹細胞由来の再生因子を用いたCell-free再生医療の開発
  • 2017/07/08 - 株式会社リバネス 徳島テックプタンター オーディエンス賞 細胞移植を伴わないCell-free 再生医療
Association Membership(s) (6):
日本口腔外科学会 ,  日本炎症・再生医学会 ,  歯科基礎医学会 ,  日本口腔科学会 ,  日本再生医療学会 ,  社団法人 日本解剖学会
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