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J-GLOBAL ID:200901078824517034   Update date: Jun. 26, 2024

Yamamoto Akihito

ヤマモト アキヒト | Yamamoto Akihito
Affiliation and department:
Research field  (1): Medical biochemistry
Research theme for competitive and other funds  (24):
  • 2021 - 2024 Analysis of joint regeneration mechanism by secretory sialic acid recognition lectin
  • 2020 - 2023 Analysis of the mechanisms of organ formation by cell-cell and cell-extracellular communications
  • 2017 - 2020 Novel therapeutic strategies for amyotrophic lateral sclerosis using human deciduous dental pulp stem cells and their active ingredients
  • 2017 - 2020 Cell fate determination of mesenchymal stem cells by extracellular mechanical stress
  • 2017 - 2020 Development of a novel treatment method for xerostomia by dental pulp stem cell-derived humoral factor
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Papers (66):
  • Xia Linze, Kano Fumiya, Hashimoto Noboru, Liu Yao, Khurel-Ochir Tsendsuren, Ogasawara Naoko, Ding Cheng, Xu Yang, Hibi Hideharu, Iwasaki Tomonori, et al. Conditioned Medium From Stem Cells of Human Exfoliated Deciduous Teeth Alleviates Mouse Osteoarthritis by Inducing sFRP1-Expressing M2 Macrophages. Stem Cells Translational Medicine. 2024. Vol.13. No.4. 399-413
  • XIA Linze, Kano Fumiya, Hashimoto Noboru, DING Cheng, XU Yang, HIBI Hideharu, Iwasaki Tomonori, Tanaka Eiji, Yamamoto Akihito. Conditioned Medium from Stem Cells of Human Exfoliated Deciduous Teeth Partially Alters the Expression of Inflammation-associated Molecules of Mouse Condylar Chondrocytes via Secreted Frizzled-related Protein 1. Journal of Oral Health and Biosciences. 2023. Vol.35. No.2. 52-60
  • Kano Fumiya, Hashimoto Noboru, Liu Yao, Xia Linze, Nishihara Takaaki, Oki Wakana, Kawarabayashi Keita, Mizusawa Noriko, Aota Keiko, Sakai Takayoshi, et al. Therapeutic benefits of factors derived from stem cells from human exfoliated deciduous teeth for radiation-induced mouse xerostomia. Scientific Reports. 2023. Vol.13. No.1. 2706-2719
  • Narwidina Anrizandy, Miyazaki Aya, Iwata Kokoro, Kurogoushi Rika, Sugimoto Asuna, Kudo Yasusei, Kawarabayashi Keita, Yamakawa Yoshihito, Akazawa Yuki, Kitamura Takamasa, et al. Iroquois homeobox 3 regulates odontoblast proliferation and differentiation mediated by Wnt5a expression. Biochemical and Biophysical Research Communications. 2023. Vol.650. 47-54
  • LIU YAO, Kano Fumiya, Hashimoto Noboru, XIA LINZE, Zhou Qiao, Feng Xingmei, Hibi Hideharu, Miyazaki Aya, Iwamoto Tsutomu, Matsuka Yoshizo, et al. Conditioned Medium From the Stem Cells of Human Exfoliated Deciduous Teeth Ameliorates Neuropathic Pain in a Partial Sciatic Nerve Ligation Model. Frontiers in Pharmacology. 2022. Vol.13. 745020-745020
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MISC (83):
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Patents (10):
Books (4):
  • Multifaceted Neuro-Regenerative Activities of Human Dental Pulp Stem Cells for Functional Recovery after Spinal Cord Injury
    INTEC 2014
  • Multifaceted Neuro-Regenerative Activities of Human Dental Pulp Stem Cells for Functional Recovery after Spinal Cord Injury
    2014
  • 歯髄幹細胞の可能性
    朝倉書店 2012
  • 再生医療叢書・歯髄幹細胞の可能性
    朝倉書店 2012
Lectures and oral presentations  (50):
  • Therapeutic benefits of factors derived from stem cells from human exfoliated deciduous teeth for radiation-induced mouse xerostomia
    (四国免疫フォーラム 2023)
  • Therapeutic benefits of factors derived from stem cells from human exfoliated deciduous teeth for radiation-induced mouse xerostomia
    (第64回歯科基礎医学会学術大会 2022)
  • Therapeutic benefits of factors derived from stem cells from human exfoliated deciduous teeth for radiation-induced mouse xerostomia
    (第76回NPO法人日本口腔科学会学術集会 2022)
  • Development of a novel treatment for rheumatoid arthritis using soluble sialic acid binding lectin
    (第76回NPO法人日本口腔科学会学術集会 2022)
  • 分泌型シアル酸認識レクチン-9とケモカインMCP-1 を用いた関節リウマチの新規治療法の開発
    (四国歯学会第59回例会 2022)
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Works (3):
  • 歯髄幹細胞由来の抗炎症性マクロファージ誘導因子を用いた末梢神経再生療法の開発
    2014 - 2016
  • 歯髄幹細胞の無血清培養上清(CM)を用いた劇症性肝炎および特発性間質性肺炎の治療法開発
    2013 - 2014
  • ヒト歯髄幹細胞の培養上清をもちいた中枢神経再生療法の開発
    2011 - 2012
Education (4):
  • - 1992 Nagasaki University
  • - 1992 Nagasaki University Graduate School, Division of Dental Research
  • - 1988 Nagasaki University School of Dentistry
  • - 1988 Nagasaki University Faculty of Dentistry
Work history (9):
  • 2016/11 - 現在 徳島大学大学院医歯薬学研究部 組織再生制御学 教授
  • 2010/04 - 2016/10 名古屋大学大学院医学研究科 口腔外科 准教授
  • 2008/08 - 2010/03 名古屋大学大学院医学研究科 口腔外科 特任准教授
  • 2005/04 - 2008/07 名古屋大学医学部生化学第二講座 非常勤講師
  • 2001/04 - 2008/07 RIKEN
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Committee career (4):
  • 2019/04 - 現在 特定非営利活動法人 日本口腔科学会 評議委員
  • 2017/04 - 現在 社団法人 日本解剖学会 教育委員
  • 2015 - 現在 日本炎症再生医学会 評議委員
  • 2010/04 - 現在 日本再生医療学会 評議委員
Awards (2):
  • 2018/02/06 - 公益財団法人康楽会 康楽賞 幹細胞由来の再生因子を用いたCell-free再生医療の開発
  • 2017/07/08 - 株式会社リバネス 徳島テックプタンター オーディエンス賞 細胞移植を伴わないCell-free 再生医療
Association Membership(s) (6):
日本口腔外科学会 ,  日本炎症・再生医学会 ,  歯科基礎医学会 ,  日本口腔科学会 ,  日本再生医療学会 ,  社団法人 日本解剖学会
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