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J-GLOBAL ID：200901080554758713   Update date: Mar. 17, 2025

Shin Yongchol

シン ヨンチョル | Shin Yongchol
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Affiliation and department：
Kogakuin University School of Advanced Engineering Department of Chemistry and Life Science

About Kogakuin University School of Advanced Engineering Department of Chemistry and Life Science


Job title： Associate Professor
Research field  (4)： Hematology and oncology ,  Functional biochemistry ,  Molecular biology ,  Biochemistry
Research keywords  (12)： metalloproteinase ,  snake vemon ,  cell migration ,  fibronectin ,  ADAMTS13 ,  VWF ,  plasmin ,  thrombosis ,  collagen ,  spheroid ,  Notch signal ,  angiogenesis
Research theme for competitive and other funds  (3)：
  • 2011 - 2013 Development of cell culture methods using sea cucumber collagen fibrils
  • 2009 - 2011 Development of artificial blood vessels using type IV collagen aggregates
  • 1998 - 1999 コラーゲンレセプターを介した血小板凝集反応の促進及び阻害蛋白質の単離とその作用機序の解明に関する研究
Papers (38)：
  • Natsuki Maeda, Takafumi Watanabe, Daisuke Suzuki, Tomohito Iwasaki, Yongchol Shin, Yasutada Imamura. Assembly of collagen fibers into contiguous dense and loose regions of subcutaneous fascia. Connective tissue research. 2025. 66. 1. 26-36
  • Kosuke Sekine, Kazuhiro Tokunaka, Arihiro Tomura, Hidemitsu Sugihara, Yuki Saijo, Yongchol Shin, Toshihiko Hayashi, Makoto Morita, Yasutada Imamura. Production of non-triple helical collagen polypeptides under Hypoxia and the Implication for Tumor. The Journal of Biochemistry. 2025
  • Kazuki Kukita, Masayoshi Sakaguchi, Hiroki Inoue, Yasutada Imamura, Yongchol Shin. Type IV collagen expression is regulated by Notch3-mediated Notch signaling during angiogenesis. Biochemical and Biophysical Research Communications. 2025. 749. 151351-151351
  • Kazuki Kukita, Nanaka Matsuzaka, Mikihisa Takai, Yasutada Imamura, Yongchol Shin. Notch signaling pathway induces expression of type IV collagen in angiogenesis. The Journal of Biochemistry. 2024. 175. 5. 539-549
  • Kenshi Togashi, Yongchol Shin, Yasutada Imamura. Non-triple helical form of type IV collagen alpha1 chain suppresses endothelial-cadherin mediated cell-to-cell junctions. The Journal of Biochemistry. 2022. 172. 3. 165-175
ｍore...
MISC (2)：
  • Yongchol Shin. Structure and fiction of von Willebrand factor: The role of C-terminal cystine knot and von Willebrand factor C domains. Japanese Journal of Thrombosis and Hemostasis. 2017. 28. 1
  • 辛英哲. 高血圧とTGF-βとの接点:細胞外マトリックス蛋白質Emilin1の機能. 蛋白質 核酸 酵素. 2006. 51. 8. 987
Lectures and oral presentations  (110)：
  • Isolation and identification of angiogenesis inhibitors in rosehip and elucidation of their inhibitory mechanisms
    (26th Congress of the International Union Biochemistry and Molecular Biology 2024)
  • Notch signaling between endothelial cells and fibroblasts induces the expression of type IV collagen in new angiogenesis model using HUVEC’s spheroid
    (26th Congress of the International Union Biochemistry and Molecular Biology. 2024)
  • 皮下Fasciaの弾性線維の可視化
    (第56回日本結合組織学会学術大会 2024)
  • 血管新生において血管内皮細胞ー線維芽細胞間のNotchシグナルはIV型コラーゲンの発現を制御する
    (第56回日本結合組織学会学術大会 2024)
  • HUVECスフェロイドを用いた新規血管新生モデルにおける血管内皮細胞-線維芽細胞間Notchシグナルを介したIV型コラーゲンの産生の制御
    (第46回日本分子生物学会年会 2023)
ｍore...
Education (3)：
  • 1993 - 1996 Okayama University The Graduate School of Natural Science and Technology
  • 1991 - 1993 Okayama University Graduate School, Division of Engineering
  • 1987 - 1991 Okayama University Faculty of Engineering Department of Biotechnology
Professional career (3)：
  • 工学士 (Okayama University)
  • 修士(工学) (Okayama University)
  • 博士(工学) (Okayama University)
Work history (5)：
  • 2008/04 - 工学院大学
  • 2005/10 - 2008/03 国立循環器病センター 研究所 研究員
  • 2000/07 - 2005/09 カリフォルニア大学 アーバイン校 研究員
  • 2000/04 - 2000/06 Ministry of Agriculture, Forestry and Fisheries
  • 1996/04 - 2000/03 Meiji Pharmaceutical University
Committee career (1)：
  • 2017/09 - 日本血栓止血学会 代議員
Awards (3)：
  • 2013/06 - 第35回日本血栓止血学会学術集会優秀ポスタ-賞
  • 2008/01 - 平成十九年度 国立循環器病センター 研究所セミナー 奨励賞
  • 2007/08 - 第5回血液・血管オルビス Young Investigator Award 最優秀賞
Association Membership(s) (4)：
日本化学会 ,  The Japanese Society of Thrombosis and Hemostasis ,  The Molecular Biology Society of Japan ,  The Japanese Biochemical Society
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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