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J-GLOBAL ID：200901083072562098
Update date: Apr. 22, 2025 Aoyama Hiroshi
アオヤマ ヒロシ | Aoyama Hiroshi
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Juntendo University Faculty of Pharmacy
About Juntendo University Faculty of Pharmacy
Job title： Professor
Research theme for competitive and other funds (8)：
- 2021 - 2024 ホスト-ゲストを利用した二重鎖核酸のX線結晶構造解析
- 2014 - 2017 Studies on molecular mechanism of paracellular pathway
- 2011 - 2014 Chain Reaction of Drug Metabolism -A Comprehensive Study on the Cooperative and Competitive Drug Metabolism by CYP Isoforms
- 2010 - 2012 Structural and functional analysis of GDE family proteins
- 2008 - 2010 A Comprehensive Study on the Drug-Drug Interactions in Drug Metabolizing Enzyme CYP
Show all
- Keisuke Tachibana, Sayaka Sugimura, Shuko Sakimura, Lin Bai, Hiroshi Aoyama, Hiroyuki Takeda, Yuki Niwa, Masahiro Nagahama, Masuo Kondoh. Size-selective permeation-enhancing modulation of the tight junction by receptor-binding domains of Clostridium perfringens enterotoxin and Clostridium perfringens iota-toxin. Tissue Barriers. 2025
- Neha Dhiman, Gamal A. I. Moustafa, Kengo Kasama, Hiroshi Aoyama, Kyohei Kanomata, Harald Gröger, Shuji Akai. Dynamic Kinetic Resolution of 2-Hydroxybiaryl Atropisomers via Lipase-Catalyzed Enantioselective O-Acylation. ChemCatChem. 2024
- Raed M. Maklad, Gamal A. I. Moustafa, Hiroshi Aoyama, Abdullah A. Elgazar. Controlling (E/Z)-Stereoselectivity of -NHC=O Chlorination: Mechanism Principles for Wide Scope Applications. Chemistry - A European Journal. 2024
- Shinji Kitagaki, Tomoki Nakayoshi, Sota Masunaka, Akane Uchida, Mai Inano, Emika Yoshida, Yusuke Washino, Hiroshi Aoyama, Keisuke Yoshida. Highly regio- and stereoselective (3 + 2) annulation reaction of allenoates with 3-methyleneindolin-2-ones catalyzed by a planar chiral [2.2]paracyclophane-based bifunctional phosphine-phenol catalyst. Organic and Biomolecular Chemistry. 2024
- Shuji Tsuruda, Takumi Sato, Hiroshi Aoyama, Natchanun Sirimangkalakitti, Shigeru Fujimura, Mitsuhiro Arisawa, Kenichi Murai. Total Synthesis and Antibacterial Activity of Marine Tris-indole Alkaloid Tulongicin A. Journal of Natural Products. 2024. 87. 6. 1556-1562
- 伊藤 恭子[新澤], 杉村 高志, 御前 智則, 蓼原 吉輝, 山本 省吾, 矢野 直峰, 花田 真, 中川 徹也, 上根 滋史, 山田 聖, et al. ウシチトクロム酸化酵素の活性型モノマー構造. 日本生化学会大会プログラム・講演要旨集. 2019. 92回. [2T06m-05]
- Shinzawa-Itoh Kyoko, Sugimura Takashi, Misaki Tomonori, Tadehara Yoshiki, Yamamoto Shogo, Hanada Makoto, Yano Naomine, Nakagawa Tetsuya, Uene Shigefumi, Yamada Takara, et al. ウシミトコンドリア由来酸素還元酵素の活性型の単量体構造(Monomeric structure of an active form of respiratory oxygen reductase from bovine mitochondria). 生物物理. 2019. 59. Suppl.1-2. S392-S392
- SHINZAWA-ITOH Kyoko, SUGIMURA Takashi, MISAKI Tomonori, TADEHARA Yoshiki, YAMAMOTO Shogo, HANADA Makoto, YANO Naomine, NAKAGAWA Tetsuya, UENE Shigefumi, YAMADA Takara, et al. Monomeric structure of an active form of respiratory oxygen reductase from bovine mitochondria. 生物物理(Web). 2019. 59. Supplement 1-2
- Xiaoling Tong, Hiroshi Aoyama, Swathy Sudhakar, Honghong Chen, Donglin Bai. The Residues in the First Extracellular Domain Play an Important Role in Transjunctional-Voltage Dependent Gating and Unitary Channel Conductance of Cx50 Gap Junction Channels. BIOPHYSICAL JOURNAL. 2015. 108. 2. 442A-442A
- Hidehiko Suzuki, Azusa Takahashi, Kyohei Matsushita, Xiangru Li, Hirofumi Tsujino, Akihiro Watari, Masuo Kondoh, Hiroshi Aoyama, Tadayuki Uno, Kiyohito Yagi. Preparation of a broad-specific claudin binder by using Clostridium perfringens enterotoxin. FASEB JOURNAL. 2012. 26
- 界面活性剤の選び方、使い方 事例集
技術情報協会 2019 ISBN:9784861047534
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3P018 X-ray structure of lipids in bovine heart Cytochrome c oxidase stabillized with 3-oxatridecyl-α-mannoside
(Seibutsu Butsuri 2005) -
3P016 Improvement of resolution of cytochrome c oxidase crystal using annealing method
(Seibutsu Butsuri 2005) -
3P113 Structural analysis of the x-ray induced photoreduction of cytochrome c oxidase
(Seibutsu Butsuri 2005) -
3P110 Strategies for collecting high resolution data of bovine heart cytochrome c oxidase
(Seibutsu Butsuri 2005) -
3P112 Analysis of the cyanide-bound structure of cytochrome c oxidase in the reduced state
(Seibutsu Butsuri 2005)
- 2024/04 - 現在 Juntendo University Faculty of Pharmacy Professor
- 2007/05 - 2024/03 大阪大学大学院薬学研究科 准教授
- 1996/04 - 2007/04 理化学研究所 研究員
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