Rchr
J-GLOBAL ID:200901083724167013   Update date: Dec. 16, 2024

MAKINO Akira

マキノ アキラ | MAKINO Akira
Affiliation and department:
Job title: Associate Professor
Research field  (1): Radiology
Research keywords  (6): 高分子化学 ,  放射化学 ,  分子イメージング ,  polymer chemistry ,  radiochemistry ,  molecular imaging
Research theme for competitive and other funds  (10):
  • 2022 - 2025 Stratification and molecular pathogenesis of dementia based on tau pathology
  • 2022 - 2025 自閉症スペクトラム障害のメカニズム解明のための脳機能イメージングプローブの創製
  • 2018 - 2022 Development of PET molecular imaging probes for elucidation of pathophysiology and development of treatment for developmental disorders
  • 2019 - 2022 小線源療法と局所の化学療法との併用を可能にする生分解性温度応答性ミセル製剤の開発
  • 2018 - 2021 Molecular imaging study investigating mechanism and pathophysiology of early stage dementia.
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Papers (83):
  • Hidehiko Okazawa, Munenobu Nogami, Shota Ishida, Akira Makino, Tetsuya Mori, Yasushi Kiyono, Masamichi Ikawa. PET/MRI multimodality imaging to evaluate changes in glymphatic system function and biomarkers of Alzheimer's disease. Scientific reports. 2024. 14. 1. 12310-12310
  • Mitsuharu Kimura, Ibuki Onishi, Yumi Yamamoto, Yohei Saito, Hiroshi Fukuda, Akira Makino, Yasushi Kiyono, Hideo Saji, Eiichi Ozeki, Shunsaku Kimura, et al. Poly(L-lactic acid)-<i>block</i>-poly(sarcosine)両親媒性ポリデプシペプチドからなる放射性ヨウ素標識ナノキャリアの合成と担癌マウス及び炎症モデルマウスにおける生体内分布. RADIOISOTOPES. 2023. 72. 2. 149-161
  • Okazawa H, Ikawa M, Mori T, Makino A, Nogami M, Kiyono Y, Kosaka H. Increased oxidative stress in the brain of early Alzheimer’s disease. JOURNAL OF NUCLEAR MEDICINE. 2023. 64. supplement 1. 150
  • Okazawa H, Ikawa M, Mori T, Makino A, Nogami M, Kiyono Y, Kosaka H. Differences in cerebral oxidative stress between early Alzheimer’s disease and healthy controls analyzed using multimodality images from PET/MRI. Journal of Cerebral Blood Flow & Metabolism. 2023. 43. supplement 1. S93
  • Munenobu Nogami, Tetsuya Tsujikawa, Hiroyuki Maeda, Nobuyuki Kosaka, Mizuho Takahashi, Naoki Kinoshita, Tetsuya Mori, Akira Makino, Yasushi Kiyono, Takamichi Murakami, et al. [18F]FES PET Resolves the Diagnostic Dilemma of COVID-19-Vaccine-Associated Hypermetabolic Lymphadenopathy in ER-Positive Breast Cancer. Diagnostics (Basel, Switzerland). 2023. 13. 11
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MISC (48):
  • 曽福智貴, 小川数馬, 三代憲司, 西井龍一, 牧野顕, 清野泰, 小谷明. オシメルチニブのコンパニオン診断を目的としたイメージングプローブの開発. 日本薬学会年会要旨集(CD-ROM). 2018. 138th
  • Yasushi Kiyono, Momoko Murata, Akira Makino, Kyo Kume, Tetsuya Mori, Tatsuya Asai, Hidehiko Okazawa. Predictive value of 3 '-deoxy-3 '-F-18-fluorothymidine uptake in colorectal cancer treated with proton irradiation under hypoxic condition. JOURNAL OF NUCLEAR MEDICINE. 2017. 58
  • 辻川 哲也, 山田 しず佳, 津吉 秀昭, 黒川 哲司, 品川 明子, 知野 陽子, 森 哲也, 牧野 顕, 清野 泰, 吉田 好雄, et al. FES PETによる子宮内膜癌および内膜異型増殖症の予後予測. JSMI Report. 2017. 10. 2. 151-151
  • 森 哲也, 矢野 良一, 伊藤 陽, 牧野 顕, 辻川 哲也, 清野 泰, 岡沢 秀彦. 学会製造基準の更新監査実施報告. 核医学. 2016. 53. Suppl. S297-S297
  • M. Martinez Pozo, A. Makino, T. Mori, H. Okazawa, Y. Kiyono. Development of a new purification protocol for radiosynthesis of 2-deoxy-2-[F-18]fluoroacetamido-D-glucopyranose. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2016. 43. S432-S432
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Patents (1):
  • 両親媒性高分子、およびその利用
Lectures and oral presentations  (90):
  • 子宮頸がんモデルマウスに対する粒子線治療の有効性と治療効果予測に関する基礎的検討
    (若狭湾エネルギー研究センター 第25回研究報告会 2023)
  • 小線源療法の現状と可能性
    (CCRT2023 第15回中部放射線医療技術学術大会 2023)
  • 温度応答性ミセルを用いた小線源療法と局所化学療法の併用療法による治療効果
    (第63回日本核医学会学術総会 2023)
  • 子宮頸がんに対する粒子線治療の有効性と18F-FLT PETを用いた早期治療効果予測についてのin vivo評価
    (第63回日本核医学会学術総会 2023)
  • 難治療性子宮頸がんに対する粒子線治療の効果と画像診断を用いた照射後早期の治療効果予測
    (第35回バイオメディカル分析科学シンポジウム 2023)
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Education (3):
  • 2003 - 2006 Kyoto University Graduate School, Division of Engineering 材料化学専攻
  • 2001 - 2003 Kyoto University Graduate School, Division of Engineering 材料化学専攻
  • 1997 - 2001 Kyoto University Faculty of Engineering Industrial Chemistry
Professional career (1):
  • Ph.D (Kyoto University)
Work history (6):
  • 2016/04 - 現在 University of Fukui Biomedical Imaging Research Center Associate Professor
  • 2012/12 - 2016/03 University of Fukui Biomedical Imaging Research Center, * Assistant Professor
  • 2011/06 - 2012/11 Kyoto University Graduate School of Pharmaceutical Sciences Assistant Professor
  • 2011/04 - 2011/05 Kyoto University Graduate School of Pharmaceutical Sciences Researcher
  • 2010/04 - 2011/03 Shimadzu Corporation Technology Research Laboratory Postdoctoral researcher
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Committee career (7):
  • 2014 - 日本薬学会 一般会員
  • 2014 - The Pharmaceutical Society of Japan member
  • 2012 - American Chemical Society 一般会員
  • 2012 - 日本分子イメージング学会 一般会員
  • 2011 - 日本核医学会 一般会員
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Awards (1):
  • 2012/05 - The Society of Polymer Science, Japan Award for Encouragement of Research in Polymer Science
Association Membership(s) (8):
The Pharmaceutical Society of Japan ,  American Chemical Society ,  Japanese Society for Molecular Imaging ,  The Japanese Society of Nuclear Medicine ,  The Chemical Society of Japan ,  The Society of Polymer Science, Japan ,  THE JAPANESE SOCIETY FOR BIOMATERIALS ,  日本薬学会
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