TAKASHI MIKI

Affiliation and department：
Job title： Professor

Research keywords (3)： insulin , obesity , Diabetes mellitus

Research theme for competitive and other funds (22)：

2022 - 2026 構造特異的胆汁酸シグナルによる新規脂肪肝抑制機構のマルチオミクス解析
2020 - 2023 Pathophysiological roles of cell senescence related gene in the polycystic kidney disease
2019 - 2022 Mechanism of proliferation, differentiation, and dedifferentiation of pancreatic beta-cells induced by local signals
2019 - 2022 Roles of KATP channels on the regulation of heat production and metabolism in adipose tissues
2016 - 2019 Mechanism of repetitive proliferation and plasticity acquisition of pancreatic beta cells: prerequisites for the maintenance of glucose homeostasis

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Papers (119)：

Junya Suzuki, Shunsuke Furuta, Yosuke Kameoka, Osamu Suzuki, Fuyu Ito, Kazuko Uno, Fukuko Kishi, Yoshio Yamakawa, Kazuyuki Matsushita, Takashi Miki, et al. Dynamics of scFv-targeted VAP2 correlating with IL-16, MIF and IL-1Ra in ANCA-associated vasculitis. Microvascular Research. 2024. 156. 104720-104720
Ryo Hatano, Xilin Zhang, Eunyoung Lee, Atsushi Kaneda, Tomoaki Tanaka, Takashi Miki. Mosaic ablation of pancreatic β-cells induces de-differentiation and repetitive proliferation of residual β-cells in adult mice. iScience. 2024. 110656-110656
Ryo Hatano, Eunyoung Lee, Hiromi Sato, Masahiro Kiuchi, Kiyoshi Hirahara, Yoshimi Nakagawa, Hitoshi Shimano, Toshinori Nakayama, Tomoaki Tanaka, Takashi Miki. Hepatic ketone body regulation of renal gluconeogenesis. Molecular Metabolism. 2024. 101934-101934
Ikki Sakuma, Hidekazu Nagano, Naoko Hashimoto, Masanori Fujimoto, Akitoshi Nakayama, Takahiro Fuchigami, Yuki Taki, Tatsuma Matsuda, Hiroyuki Akamine, Satomi Kono, et al. Identification of genotype-biochemical phenotype correlations associated with fructose 1,6-bisphosphatase deficiency. Communications biology. 2023. 6. 1. 787-787
Hanna Deguchi-Horiuchi, Sawako Suzuki, Eun Young Lee, Takashi Miki, Noriko Yamanaka, Ichiro Manabe, Tomoaki Tanaka, Koutaro Yokote. Pancreatic β-cell glutaminase 2 maintains glucose homeostasis under the condition of hyperglycaemia. Scientific reports. 2023. 13. 1. 7291-7291

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MISC (99)：

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Education (2)：

Professional career (1)：

Work history (7)：

2010/04 - 現在 Department of Medical Physiology, Graduate School of Medicine, Chiba University Professor
2007/12 - 2010/03 Department of Medical Physiology, Graduate School of Medicine, Chiba University
2003/12 - 2007/09 神戸大学助教授大学院医学系研究科(脳科学講座細胞・神経生理学分野)
2003/06 - 2003/11 千葉大学助教授大学院医学研究院(先端応用医学講座細胞分子医学分野)
2001/04 - 千葉大学助教授遺伝子実験施設

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