Izumi Masayuki

イズミマサユキ | Izumi Masayuki

Affiliation and department：
Job title：教授
Homepage URL (1)： http://science.cc.kochi-u.ac.jp/?course=4088

Research field (4)： Chemical biology , Molecular biochemistry , Biochemistry , Structural biochemistry

Research keywords (7)： Chemical Protein Synthesis , Glycopeotein , Ubiquitin , Organic synthesis , Mass spectrometry , carbohydrate chemistry , Enzymatic synthesis

Research theme for competitive and other funds (9)：

2024 - 2027 Sequential peptide ligation using spontaneous deprotection reaction by intramolecular selenium
2021 - 2026 New Synthetic Methods for Glycoproteins and the Integrated Approaches to Elucidate the Functions of Post-translational Modifications
2021 - 2024 Evaluation of the effect of natural or unnatural glycosylation modes on the activity of glycoproteins
2021 - 2024 ynthesis of modified protein using chemoselective ligation between d-selenolysine and selenoester
2017 - 2021 Development of new synthetic method of ubiquitinated glycoprotein probe using specific reactivity of selenium

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Papers (79)：

Tatsunari Akiyama, Yusuke Tanaka, Ryo Okamoto, Yasuhiro Kajihara, Masayuki Izumi. Isopeptide bond formation mediated by δ-selenolysine for chemical ubiquitination. Frontiers in Chemistry. 2023. 11
Naoki Tsutsumi, Akitaka Ito, Yosuke Niko, Yui Bando, Kiyonori Takahashi, Masato Ikeda, Kaori Yoneyama, Takayoshi Nakamura, Masayuki Izumi, Rika Ochi. Glycolipid-Type Amphiphiles with a Small Anilinochloromaleimide-Based Luminogen Exhibiting Aggregation-Induced Emission. ChemistrySelect. 2022. 7. 42
Yuta Maki, Yuiko Otani, Ryo Okamoto, Masayuki Izumi, Yasuhiro Kajihara. Isolation and characterization of high-mannose type glycans containing five or six mannose residues from hen egg yolk. Carbohydrate Research. 2022. 521. 108680-108680
Naoki Tsutsumi, Akitaka Ito, Azumi Ishigamori, Masato Ikeda, Masayuki Izumi, Rika Ochi. Synthesis and Self-Assembly Properties of Bola-amphiphilic Glycosylated Lipopeptide-Type Supramolecular Hydrogels Showing Colour Changes Along with Gel-Sol Transition. International Journal of Molecular Sciences. 2021. 22. 4. 1860-1860
Yuta Maki, Ryo Okamoto, Masayuki Izumi, Yasuhiro Kajihara. Chemical Synthesis of an Erythropoietin Glycoform Having a Triantennary N-Glycan: Significant Change of Biological Activity of Glycoprotein by Addition of a Small Molecular Weight Trisaccharide. Journal of the American Chemical Society. 2020

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MISC (4)：

谷川智樹, 石田雅司, 伊藤亮孝, 仁子陽輔, 和泉雅之, 越智里香. Development of boronic-acid-containing OFF/ON-type fluorescent molecular probes that enable hydrogen peroxide detection. 日本化学会春季年会講演予稿集(Web). 2024. 104th
Tatsuto Kiuchi, Ryo Okamoto, Masayuki Izumi, Akira Seko, Yukishige Ito, Yasuhiro Kajihara. Synthetic Study of Erythropoietin Having High Mannose-type Oligosaccharide by Chemical Methodology. GLYCOBIOLOGY. 2014. 24. 11. 1119-1119
Sato Takahiro, Izumi Masayuki, Yamanaka Shusuke, Yoshinari Nobuto. Introduction to "Upgrade Seminar in Chemistry" Offered in Department of Chemistry, School of Science. 2014. 2. 69-74
M Izumi, H Uzawa, H Itoh, S Yokoyama, H Mori, N Minoura. Gb2 disaccharide-coated sensor chip for verotoxin detection. GLYCOBIOLOGY. 2004. 14. 11. 1197-1198

Patents (2)：

Books (6)：

グライコバイオロジーの新展開 4 糖タンパク質化学合成の医学への応用
2017
糖タンパク質の品質管理の仕組み-糖タンパク質の精密化学合成を利用して-
2015
Introduction to " Upgrade Seminar in Chemistry " Offered in Depa rtment of Chemistry, School of Science
2014
合成法の開発と展望 1.糖タンパク質の有機合成化学
2013
化学でバイオテクノロジーへ挑戦!! 高純度糖タンパク質の精密化学合成
2013

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Lectures and oral presentations (185)：

Chemical Synthesis of Lectin PhoSL Analog containing Diselenide Bond
(Chemical Protein Synthesis Symposium 2024 2024)
Synthetic Studies of Interleukin-8 Analog Having High Mannose-Type N-glycan
(日本化学会春季年会講演予稿集(Web) 2024)
Chemical Synthesis of a Lectin PhoSL Analog with Diselenide Bond
(日本化学会春季年会講演予稿集(Web) 2024)
One-pot Synthesis of Peptide Thiolactone from Hydrazide via Peptide Thioester or Selenoester
(日本化学会春季年会講演予稿集(Web) 2024)
Development of boronic-acid-containing OFF/ON-type fluorescent molecular probes that enable hydrogen peroxide detection
(日本化学会春季年会講演予稿集(Web) 2024)

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Education (3)：

1993 - 1996 Tokyo Institute of Technology Graduate School of Bioscience and Biotechnology Ph. D. course
1991 - 1993 Tokyo Institute of Technology Graduate School of Bioscience and Biotechnology Master course
1987 - 1991 Tokyo Institute of Technology Faculty of Science Under graduate, Department of Life Science

Professional career (1)：

博士(理学) (東京工業大学)

Work history (12)：

2022/04 - 現在 Kochi University Research and Education Faculty Multidisciplinary Science Cluster Interdisciplinary Science Unit The head of a department
2017/04 - 現在 Kochi University Faculty of Science and Technology Department of Chemistry and Biotechnology Professor
2017/04 - 現在 Kochi University Professor
2019/04 - 2021/03 Kochi University Faculty of Science and Technology Department of Chemistry and Biotechnology The head of a department
2015/04 - 2017/03 Osaka University Graduate School of Science Associate Professor

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Committee career (3)：

2021/11 - 2023/10 日本化学会代議員
2019/03 - 2021/02 日本化学会中国四国支部地区幹事
2013/03 - 2015/02 日本化学会近畿支部幹事

Awards (2)：

2014/07 - 大阪大学総長奨励賞
2006 - GlycoTOKYO Encuragement award

Association Membership(s) (4)：

日本ペプチド学会 , アメリカ化学会 , 日本化学会 , 日本糖質学会

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