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J-GLOBAL ID:200901085267939415   Update date: Apr. 02, 2025

Izumi Masayuki

イズミ マサユキ | Izumi Masayuki
Affiliation and department:
Job title: 教授
Homepage URL  (1): http://science.cc.kochi-u.ac.jp/?course=4088
Research field  (4): Chemical biology ,  Molecular biochemistry ,  Biochemistry ,  Structural biochemistry
Research keywords  (7): Chemical Protein Synthesis ,  Glycopeotein ,  Ubiquitin ,  Organic synthesis ,  Mass spectrometry ,  carbohydrate chemistry ,  Enzymatic synthesis
Research theme for competitive and other funds  (9):
  • 2024 - 2027 Sequential peptide ligation using spontaneous deprotection reaction by intramolecular selenium
  • 2021 - 2026 New Synthetic Methods for Glycoproteins and the Integrated Approaches to Elucidate the Functions of Post-translational Modifications
  • 2021 - 2025 ynthesis of modified protein using chemoselective ligation between d-selenolysine and selenoester
  • 2021 - 2024 Evaluation of the effect of natural or unnatural glycosylation modes on the activity of glycoproteins
  • 2017 - 2021 Development of new synthetic method of ubiquitinated glycoprotein probe using specific reactivity of selenium
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Papers (82):
  • Kotoyo Yamashita, Akitaka Ito, Masashi Ishida, Yuki Shintani, Masato Ikeda, Shingo Hadano, Masayuki Izumi, Rika Ochi. Stereoisomerism-dependent gelation and crystal structures of glycosylated N-methylbromomaleimide-based supramolecular hydrogels. Soft Matter. 2025
  • Yuta Maki, Akihiro Manbo, Abe Junpei, Hiroki Nobutou, Kohtaro Hirao, Ryo Okamoto, Masayuki Izumi, Shusuke Yamanaka, Mitsutaka Okumura, Yasuhiro Kajihara. Harnessing Free Sulfate Groups in Glycosylation Reactions. Angewandte Chemie (International ed. in English). 2024. e202416743
  • Yuta Chabatake, Tomoki Tanigawa, Yuto Hirayama, Ryo Taniguchi, Akitaka Ito, Kiyonori Takahashi, Shin-ichiro Noro, Tomoyuki Akutagawa, Takayoshi Nakamura, Masayuki Izumi, et al. 15-Crown-5-ether-based supramolecular hydrogel with selection ability for potassium cation via gelation and colour change. Soft Matter. 2024
  • Tatsunari Akiyama, Yusuke Tanaka, Ryo Okamoto, Yasuhiro Kajihara, Masayuki Izumi. Isopeptide bond formation mediated by δ-selenolysine for chemical ubiquitination. Frontiers in Chemistry. 2023. 11
  • Naoki Tsutsumi, Akitaka Ito, Yosuke Niko, Yui Bando, Kiyonori Takahashi, Masato Ikeda, Kaori Yoneyama, Takayoshi Nakamura, Masayuki Izumi, Rika Ochi. Glycolipid-Type Amphiphiles with a Small Anilinochloromaleimide-Based Luminogen Exhibiting Aggregation-Induced Emission. ChemistrySelect. 2022. 7. 42
more...
MISC (3):
  • Tatsuto Kiuchi, Ryo Okamoto, Masayuki Izumi, Akira Seko, Yukishige Ito, Yasuhiro Kajihara. Synthetic Study of Erythropoietin Having High Mannose-type Oligosaccharide by Chemical Methodology. GLYCOBIOLOGY. 2014. 24. 11. 1119-1119
  • Sato Takahiro, Izumi Masayuki, Yamanaka Shusuke, Yoshinari Nobuto. Introduction to "Upgrade Seminar in Chemistry" Offered in Department of Chemistry, School of Science. 2014. 2. 69-74
  • M Izumi, H Uzawa, H Itoh, S Yokoyama, H Mori, N Minoura. Gb2 disaccharide-coated sensor chip for verotoxin detection. GLYCOBIOLOGY. 2004. 14. 11. 1197-1198
Patents (2):
Books (6):
  • グライコバイオロジーの新展開 4 糖タンパク質化学合成の医学への応用
    2017
  • 糖タンパク質の品質管理の仕組み-糖タンパク質の精密化学合成を利用して-
    2015
  • Introduction to " Upgrade Seminar in Chemistry " Offered in Depa rtment of Chemistry, School of Science
    2014
  • 合成法の開発と展望 1.糖タンパク質の有機合成化学
    2013
  • 化学でバイオテクノロジーへ挑戦!! 高純度糖タンパク質の精密化学合成
    2013
more...
Lectures and oral presentations  (191):
  • One-pot synthesis of diselenide analog of lectin PhoSL by consecutive diselenide-selenoester ligation
    (The 61th Japanese Peptide Symposium 2024)
  • Chemical synthesis of core fucose-binding lectin PhoSL containing selenocysteine residues
    (日本糖質学会年会要旨集 2024)
  • Separation of Fmoc-protected high-mannose-type glycosyl-asparagines prepared from hen egg yolk
    (日本糖質学会年会要旨集 2024)
  • Chemical Synthesis of Lectin PhoSL Analog containing Diselenide Bond
    (Chemical Protein Synthesis Symposium 2024 2024)
  • Synthetic Studies of Interleukin-8 Analog Having High Mannose-Type N-glycan
    (日本化学会春季年会講演予稿集(Web) 2024)
more...
Education (3):
  • 1993 - 1996 Tokyo Institute of Technology Graduate School of Bioscience and Biotechnology Ph. D. course
  • 1991 - 1993 Tokyo Institute of Technology Graduate School of Bioscience and Biotechnology Master course
  • 1987 - 1991 Tokyo Institute of Technology Faculty of Science Under graduate, Department of Life Science
Professional career (1):
  • 博士(理学) (東京工業大学)
Work history (12):
  • 2022/04 - 現在 Kochi University Research and Education Faculty Multidisciplinary Science Cluster Interdisciplinary Science Unit The head of a department
  • 2017/04 - 現在 Kochi University Faculty of Science and Technology Department of Chemistry and Biotechnology Professor
  • 2017/04 - 現在 Kochi University Professor
  • 2019/04 - 2021/03 Kochi University Faculty of Science and Technology Department of Chemistry and Biotechnology The head of a department
  • 2015/04 - 2017/03 Osaka University Graduate School of Science Associate Professor
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Committee career (3):
  • 2021/11 - 2023/10 日本化学会 代議員
  • 2019/03 - 2021/02 日本化学会 中国四国支部地区幹事
  • 2013/03 - 2015/02 日本化学会 近畿支部幹事
Awards (2):
  • 2014/07 - 大阪大学総長奨励賞
  • 2006 - GlycoTOKYO Encuragement award
Association Membership(s) (4):
日本ペプチド学会 ,  アメリカ化学会 ,  日本化学会 ,  日本糖質学会
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