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J-GLOBAL ID:200901085832854500   Update date: Dec. 25, 2024

Torii Satoru

トリイ サトル | Torii Satoru
Affiliation and department:
Job title: Junior Associate Professor
Homepage URL  (2): http://www.tmd.ac.jp/mri/pcb/index.htmlhttps://reins.tmd.ac.jp/html/100008392_en.html
Research field  (2): Cell biology ,  Neuroscience - general
Research keywords  (13): Substantia nigra ,  phosphatase ,  kinase ,  phosphorylation ,  CHCHD2 ,  mitochondria ,  Casein kinase ,  PPM1D/Wip1 ,  Ulk1 ,  signal transduction ,  apoptosis ,  autophagy ,  Parkinson's disease
Research theme for competitive and other funds  (11):
  • 2025 - 2026 パーキンソン病の発症機構の解明と治癒化合物の開発
  • 2023 - 2026 Elucidation of physiological functions of Ulk1 phosphorylation which acts as a molecular switch leading to alternative autophagy
  • 2018 - 2021 新規オートファジーを制御するUlk1のリン酸化解析とその生理的・病理的意義の解明
  • 2018 - 2020 新規オートファジーを制御するUlk1のリン酸化解析とその生理的・病理的意義の解明
  • 2014 - 2017 Elucidation of pathogenic mechanism of Parkinson's disease through analysis of IPAS, a novel substrate of Parkin
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Papers (47):
  • Kazuma Ohshima, Satoru Torii, Shigeomi Shimizu. Presence of Gut Microbiota Worsens D-Galactosamine and Lipopolysaccharide-Induced Hepatic Injury in Mice. Genes to cells : devoted to molecular & cellular mechanisms. 2025. 30. 1. e13183
  • Kohjin Suzuki, Naoki Watanabe, Satoru Torii, Satoko Arakawa, Kiyosumi Ochi, Shun Tsuchiya, Kazuhiro Yamada, Yoko Kawamura, Sadao Ota, Norio Komatsu, et al. BCR::ABL1-induced mitochondrial morphological alterations as a potential clinical biomarker in chronic myeloid leukemia. Cancer science. 2024
  • Tomoki Yanagi, Hiroaki Kikuchi, Koh Takeuchi, Koichiro Susa, Takayasu Mori, Motoko Chiga, Kouhei Yamamoto, Asuka Furukawa, Takumi Kanazawa, Yuki Kato, et al. ULK1-regulated AMP sensing by AMPK and its application for the treatment of chronic kidney disease. Kidney international. 2024. 106. 5. 887-906
  • Tatsuya Hasegawa, Masaya Nakashima, Satoru Torii, Shinya Honda, Shigeomi Shimizu. Photo-protective role of ATG5/ATG7-independent alternative autophagy in human keratinocytes. Autophagy Reports. 2024. 3. 1
  • Tatsuya Hasegawa, Saori Noguchi, Masaya Nakashima, Masashi Miyai, Makiko Goto, Yuko Matsumoto, Satoru Torii, Shinya Honda, Shigeomi Shimizu. Alternative autophagy dampens UVB-induced NLRP3 inflammasome activation in human keratinocytes. Journal of Biological Chemistry. 2024
more...
MISC (17):
Books (1):
  • 週刊医学のあゆみ 細胞死のすべて
    2022
Lectures and oral presentations  (29):
  • 新規オートファジーに必須なUlk1のリン酸化とネクロプトーシス実行因子RIPK3の関与
    (第1回 細胞死コロキュアム 2020)
  • Regulation of phosphorylation of Ulk1 in alternative autophagy
    (The 15th International Symposium of the Institute Network for Biomedical Sciences 2020)
  • RIPK3によるDNA傷害依存的な新規オートファジーの制御
    (第93回日本生化学会大会 2020)
  • Regulation of DNA damage-induced apoptosis by autophagy
    (2019)
  • The role of PPM1D in regulating DNA damage-induced autophagy.
    (Workshop on Frontiers in Phosphatase Research and Drug Discovery (ICPP13) 2018)
more...
Works (1):
  • 細胞外環境依存的な細胞死における低酸素応答抑制因子IPASによる新規細胞死制御機構の解析
    2009 - 2010
Education (3):
  • 2004 - 2006 Kyoto University
  • 2001 - 2003 Kyoto University
  • 1997 - 2001 Kyoto University Faculty of Science
Professional career (1):
  • 博士(生命科学) (京都大学)
Work history (7):
  • 2021/01 - 現在 Tokyo Medical and Dental University
  • 2022/04 - 2024/03 東京医科歯科大学難治疾患研究所 難病基盤・応用研究プロジェクト第4期 研究代表者(兼任)
  • 2017/04 - 2020/12 Tokyo Medical and Dental University Medical Research Institute Pathophysiology Pathological Cell Biology Junior Associate Professor
  • 2017/01 - 2017/03 Tokyo Medical and Dental University Medical Research Institute Pathophysiology Pathological Cell Biology Junior Associate Professor
  • 2014/04/01 - 2016/12/31 Tokyo Medical and Dental University Medical Research Institute Pathophysiology Pathological Cell Biology Project Junior Associate Professor
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Awards (7):
  • 2024/07 - 日本Cell Death学会 第32回日本Cell Death学会学術集会 ベストプレゼンテーション賞
  • 2024/03 - 東京医科歯科大学難治疾患研究所 2023年難治疾患研究所優秀論文賞
  • 2020/09 - 東京医科歯科大学 次世代研究者育成ユニット
  • 2019/09 - 東京医科歯科大学 次世代研究者育成ユニット
  • 2018/09 - 東京医科歯科大学 次世代研究者育成ユニット パーキンソン病原因遺伝子CHCHD2の遺伝子変異から発症に至る病態メカニズムの解明と治療法開発研究
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Association Membership(s) (4):
日本ミトコンドリア学会 ,  日本Cell death学会 ,  日本生化学会 ,  日本分子生物学会
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