2017 - 2020 The deterioration prediction and the preservation protocol design of liquid biopsy specimens for the high-quality non-cryogenic dry preservation
2013 - 2015 Method for rapid-dry fixation of RNA and protein for individualized medicine
2012 - 2015 Elucidation of biological functions of LEA proteins as a desiccation protectant and their industrial application
2010 - 2015 Establishment of the methodology for design and growth of implantable pancreatic beta cell or liver cell tissues in vitro
2011 - 2014 Measurement and Analysis of Bound Water Dynamics in Lyoprotective agents for Preserving Desiccated Biomaterials at Room Temperature
2011 - 2012 Development of electroinjection method for loading single fish egg with cryo- and lyoprotective agents
2008 - 2010 Development of the high performance electrofusion device for loading lyo-, cryoprotective agents in vivo
2008 - 2009 誘電分光による生体内の結合水測定と生体の劣化予測に関する研究
2005 - 2007 細胞とリポソームの電場制御融合による耐凍結・乾燥性糖類の細胞膜輸送促進
2004 - 2007 Development of optimum freezing process prediction model based on high-precision three-dimensional internal structure and component information
2004 - 2005 人工臓器における大規模集積流路ネットワークの形態設計・評価に関する研究
2002 - 2005 Active Enhancement of Microscale Heat and Mass Transport in the Process of Cryopreservation and Establishment of the Method of Viability Assessment
2001 - 2005 Development of a Heat Recovery System Utilizing Heat Transport and Thermoelectric Devices
2004 - 2004 生命系のホメオスタシスを構築するトランスファロームのシステム生物学
2002 - 2003 磁気共鳴を用いた非平衡状態における氷晶の相変化のアクティブ制御に関する研究
2000 - 2001 電気物性を利用した氷点下における氷結晶形態の経時変化の非破壊計測
2000 - 2001 Development of Thin and Flexible Heat-Spreading Plate
1998 - 2000 Study of boiljing phenomena at high heat flues focusing on evaporation in interline region
1998 - 1999 相変化に伴う自励振動を応用した高性能熱輸送デバイスの作動原理の解明
1997 - 1998 Research on utilization of high-performance heat transport device
1996 - 1997 Development of Micro Heat-Transport Device Using Oscillation-Induced Heat-Transport Phenomena
熱輸送デバイスに関する研究
生体・食品の長期高品位保存
Study of oscillation induced heat transpot device
Cryopreservation of biological material&foods
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Papers (71):
Kosei Kawai, Ryo Shirakashi. Water rotational relaxation time measurement by shortwave infrared micro spectroscopy(SWIR) at sub-zero temperatures. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2024. 322. 124707-124707
Yuanheng Zhao, Hiroaki Matsuura, Ryo Shirakashi. Water rotational relaxation time of preservation solutions relates to storage lifespan of cells in isochoric cryopreservation system. Food and Bioproducts Processing. 2024. 147. 199-208
Kang Hu, Ryo Shirakashi. Determination of the first hydration layer from the perspective of local electric field reorientation. Chemical Physics Letters. 2024. 845. 141302-141302
Junkai Zhang, Ryo Shirakashi. Measurement of the rotational relaxation time of intracellular water in dried yeast and Jurkat cells by near infrared spectroscopy. Biochemical and Biophysical Research Communications. 2024. 710. 149857-149857
Kiyoshi Takano, Ryo Shirakashi. Development of dry-preservation technology for biological protein at room temperature. ACRA 2018 - 9th Asian Conference on Refrigeration and Air-Conditioning. 2018
John W. Rose, Shigefumi Nishio, Ryo Shirakashi, Yoshio Utaka. Professor Ichiro Tanasawa (1936-2014) In Memoriam. INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER. 2015. 85. 916-917
Takano Kiyoshi, Shirakashi Ryo. E111 Study on Conditions for Forming Giant Unilamellar Vesicles under Flow Field. Procee[d]ings of Thermal Engineering Conference. 2013. 2013. 131-132
Ryo Shirakashi, Kiyoshi Takano, Christophe Provin, Yasuyuki Sakai, Teruo Fujii. MEASUREMENT OF CELLULAR ADHESION RATIOS UNDER SHEAR FLOW ON VARIOUS SUBSTRATES. PROCEEDINGS OF THE ASME/JSME 8TH THERMAL ENGINEERING JOINT CONFERENCE 2011, VOL 1 PTS A AND B. 2011. 25-31
Ryo Shirakashi, Tomomi Yoshida, Christophe Provin, Kiyoshi Takano, Yasuyuki Sakai, Teruo Fujii. Steady measurement of glucose metabolism of hepatocyte. PROCEEDINGS OF THE ASME/JSME THERMAL ENGINEERING SUMMER HEAT TRANSFER CONFERENCE 2007, VOL 3. 2007. 65-70