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J-GLOBAL ID:200901090086154827   Update date: Aug. 18, 2024

Shibagaki Yoshio

シバガキ ヨシオ | Shibagaki Yoshio
Affiliation and department:
Job title: Lecturer/Junior Associate Professor
Research field  (5): Virology ,  Pharmaceuticals - health and biochemistry ,  Molecular biology ,  Virology ,  Molecular biology
Research keywords  (8): drug screening ,  anti-influenza viral drug ,  proteomic technology ,  protein phosphorylation ,  mRNA cap structure ,  mRNA capping enzyme ,  transcriptional factor ,  transcriptional regulation
Research theme for competitive and other funds  (13):
  • 2017 - 2020 Clinicopathologic approach to pediatric membranous nephropathy associated with congenital anomaly of kidney and urinary tract and the antigenic target
  • 2015 - 2018 Anti-Inflienza drug screening targetted by cap-snatching mechanism
  • 2011 - 2013 A convenient proteomic system for kinase substrate identification
  • 2002 - 2004 Involvement of mRNA capping enzyme in transcription initiation
  • 1999 - 2000 Sructural and function analysis of yeast mRNA capping enzyme in transcription reaction.
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Papers (35):
  • Hitomi Okamoto, Yoichi Tanaka, Yoshio Shibagaki, Satoshi Kuronuma, Yusuke Miyatani, Satoko Umeda, Emi Mishiro-Sato, Osamu Takeuchi, Seisuke Hattori, Taku Kobayashi, et al. Measurement of the intracellular active metabolites of thiopurine drugs to evaluate the enzymatic activity of nudix hydrolase 15 in human blood samples. Journal of Chromatography B. 2024. 1234. 123993-123993
  • Naoyuki Iida, Madoka Kawahara, Riku Hirota, Yoshio Shibagaki, Seisuke Hattori, Yuko Morikawa. A Proteomic Analysis of Detergent-Resistant Membranes in HIV Virological Synapse: The Involvement of Vimentin in CD4 Polarization. Viruses. 2023. 15. 6
  • Yasukazu Takanezawa, Ryohei Harada, Yoshio Shibagaki, Yui Kashiwano, Ryosuke Nakamura, Yuka Ohshiro, Shimpei Uraguchi, Masako Kiyono. Protective function of the SQSTM1/p62-NEDD4 complex against methylmercury toxicity. Biochemical and biophysical research communications. 2022. 609. 134-140
  • Tatsuhiro Sato, Satomi Mukai, Haruna Ikeda, Emi Mishiro-Sato, Ken Akao, Toshiyuki Kobayashi, Okio Hino, Wataru Shimono, Yoshio Shibagaki, Seisuke Hattori, et al. Silencing of SmgGDS, a Novel mTORC1 Inducer That Binds to RHEBs, Inhibits Malignant Mesothelioma Cell Proliferation. Molecular Cancer Research. 2021. 19. 5. 921-931
  • Nobuhiro Koyama, Yoshio Shibagaki, Mitsuru Okuwaki, Seisuke Hattori, Hiroshi Tomoda. Discovery of Oosporein as a New Inhibitor of Influenza Virus Capsnatching Activity. Int J Pharma Sci Res. 2021. 7. 137
more...
MISC (28):
  • 堤弘次, 中村遥, 北川裕介, 鈴木柚里奈, 柴垣芳夫, 服部成介, 太田安隆. ArfGAP因子AGAP1はArfの不活性化およびRacGAP因子FilGAPとの結合を介して細胞形態を制御する. 日本生化学会大会(Web). 2017. 90th
  • 宮崎碧, 堤弘次, 柴垣芳夫, 服部成介, 太田安隆. 微小管モータータンパク質Kinesin-5は創傷治癒において細胞運動に抑制的に働く. 日本生化学会大会(Web). 2017. 90th
  • 三城恵美, 佐藤龍洋, 柴垣芳夫, 服部成介. Proteomic identification of novel tyrosine-sulfated proteins. 日本プロテオーム学会大会プログラム・抄録集. 2015. 2015 (Web)
  • 酵母mRNAキャッピング酵素βサブユニットの機能解析. 生化学. 2000. 72. 8. 979
  • Functional analysis of yeast mRNA capping enzyme βsubunit. 2000. 72. 8. 979
more...
Patents (1):
  • 新規キャッピング酵素並びに、キャップ化RNAの製造法及びその用途
Books (5):
  • レーニンジャー新生化学第7版
    廣川書店 2019
  • レーニンジャー新生化学第6版
    廣川書店 2016
  • レーニンジャー新生化学第5版
    廣川書店 2014
  • レーニンジャー新生化学第4版下巻
    広川書店 2006
  • Structure and function of yeast mRNA capping enzyme(共著)
    Nucleic Acid Metylation 1991
Lectures and oral presentations  (15):
  • FilGAP, aGAP for Rac asociates with Afadin and maintains the Actin cytoskeltal integrity of Kidney podocytes
    (The 35th Annual Meeting of the Molecular Biology Society of Japan 2012)
  • FilGAP, aGAP for Rac asociates with Afadin and maintains the Actin cytoskeltal integrity of Kidney podocytes
    (The 35th Annual Meeting of the Molecular Biology Society of Japan 2012)
  • Cross-talk of Rac1 and Arf1 Signaling by Interaction Between FilGAP and AGAP1.
    (The 35th Annual Meeting of the Molecular Biology Society of Japan 2012)
  • mTORC2 Regulates Cell Migration Through Filamin A
    (The 35th Annual Meeting of the Molecular Biology Society of Japan 2012)
  • The involvement of Rheb Small GTPase in Nucleotide Biosynthesis
    (The 35th Annual Meeting of the Molecular Biology Society of Japan 2012)
more...
Professional career (2):
  • 理学博士 (東京大学)
  • 理学修士 (東京大学)
Work history (2):
  • 1991 - 現在 Kitasato University School of Pharmaceutical Sciences Lecturer
  • 1994/09 - 1996/09 UCLA, University of California Los Angeles UCLA School of Medicine, Dept. of Molecular and Medical Pharmacology Postdoctral Fellow
Association Membership(s) (3):
日本薬学会 ,  日本分子生物学会 ,  日本生化学会
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