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J-GLOBAL ID：200901091684710323 Update date: Mar. 16, 2025

Miyazaki Tatsuhiko

ミヤザキタツヒコ | Miyazaki Tatsuhiko

Affiliation and department：
Job title： Professor,

Research field (2)： Experimental pathology , Human pathology

Research keywords (12)： Developmental mechanism of autoimmune diseases; clinicopathological analyses of bone and soft tissue tumors / Pathology, lecture and experiment , Developmental mechanism of autoimmune diseases; Cell free protein synthesis; clinicopathological analyses of bone and soft tissue tumors / Pathology, lecture and experiment , Developmental mechanism of autoimmune diseases; Cell free protein synthesis; clinicopathological analyses of bone and soft tissue tumors / Pathology, lecture and experiment , Clinicopathological analyses of bone and soft tissue tumors; Analyses for the developmental mechanism of autoimmune diseases / Pathology, lecture and experiment , Span80 vesicle , drug delivery system , tumor of the bone and soft tissue , cell free protein synthesis , autoimmune disease , Span80ベシクル , ドラッグデリバリーシステム , 無細胞蛋白合成

Research theme for competitive and other funds (34)：

2022 - 2028 先端モデル動物支援プラットフォーム
2022 - 2025 Comprehensive genetic analysis of collagen disease therapeutic model using recombinant-inbred mice
2019 - 2022 Pathogenomic analyses of the collagen disease therapeutic model using recombinant inbred mice.
2016 - 2021 先端モデル動物支援プラットフォーム
2016 - 2019 リコンビナントインブレッド系マウスを用いた膠原病治療反応多様性の解析

2015 - 2016 難治性血管炎ゲノムマーカーの同定と評価および血管炎の疾患活動性や治療反応性の指標となる病理学的所見の抽出とそれを用いた病期分類法の開発ならびに評価

2013 - 2016 膠原病疾患モデル組換え近交系マウスを用いた膠原病治療法の開発

2013 - 2015 膠原病疾患モデル組換え近交系マウスを用いた膠原病治療法の開発

2012 - 2014 Absolute Quantification of Transmembrane Protein Shedding and Its Application to the Monitoring of Chronic Inflammation

2009 - 2014 Clarification of factors governing sensitivity of disruption of intracellular receptor-xenobiotic metabolizing enzyme signaling pathways by chemical substances

2011 - 2013 Developement of a caffeine-assisted chemotherapy against bone tumors using a novel DDS by Span80 vesicles

2010 - 2012 Development of a glomerulonephritis therapeutic modelwith novel protein analogs targeting the polymorphic binding site of osteopontin (Opn)

2008 - 2010 Resistance genes to collagen disease in a wild mice-derived inbred strain MSM/Ms

2007 - 2008 Span80ベシクルを用いた悪性骨・軟部腫瘍治療の萌芽的研究

2007 - 2008 Development of a therapeutic model for collagen diseases targeting amino acid polymorphism of osteopontin

2006 - 2007 Establishment of a novel recombinant inbred strain of mice MXH/lpr with genetic dissociation of the complex pathological and pathophysiological phenotypes of collagen disease under a polygene network

2007 - Analyses for Immunomodulation by glycosphyngolipid

2007 - 糖脂質を用いた免疫機能修飾法の研究

2005 - 2006 An integrated analyses on the implication of structural and promoter polymorphism of osteopontin modification

2006 - Establishent of a new drug delivery system by using detergent Span80 vesicle.

2006 - 界面活性剤Span80ベシクルを用いた新たなdrug delivery systemの構築

2003 - 2004 新たな漫性膵炎モデル:Toll-like receptor3シグナル系を包括するゲノム解析

2003 - 2004 Analyses of responsible domain inducing functional difference of polymorphic murine osteopontin protein

2003 - Functional analyses of polymorphic protein with cell free protein synthesis system using wheat germ

2003 - コムギ胚芽を用いた無細胞蛋白合成システムを用いた多型タンパク質の機能解析

2001 - 2002 Pathogenomics of collagen disease using synthetic polymorphic proteins and BAG transgenic mice

1999 - 2000 Role of the allelic polymorphism of osteopontin gene on the pathogenesis and development of autoimmune glomerulonephritis

1999 - 2000 Susceptibility gene loci to collagen disease in a murine model

Clinicopathological studies on tumor of the bone and soft tissue

Clinicopathologica analysis of vasculitis syndrome and autoimmune glomerulonephritis

Study on development of autoimmune duseases

骨・軟部腫瘍の臨床病理学的研究

血管炎症候群,自己免疫性糸球体腎炎の病態解析

膠原病疾患群の発症・進展のメカニズムに関する研究

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Papers (379)：

Susumu Endo, Hiromitsu Kanamori, Akihiro Yoshida, Genki Naruse, Shingo Komura, Shingo Minatoguchi, Takatomo Watanabe, Tomonori Kawaguchi, Yoshihisa Yamada, Atsushi Mikami, et al. Sodium-Glucose Cotransporter 2 inhibitor Empagliflozin Enhances Autophagy and Reverses Remodeling in Hearts with Large, Old Myocardial Infarctions. European journal of pharmacology. 2025. 177355-177355
Kuroki Masashi, Iinuma Ryota, Okuda Hiroshi, Terazawa Kosuke, Shibata Hirofumi, Mori Ken-ichi, Ohashi Toshimitsu, Makiyama Akitaka, Futamura Manabu, Miyazaki Tatsuhiko, et al. Comprehensive Genome Profile testing in Head and Neck Cancer. Nippon Jibiinkoka Tokeibugeka Gakkai Kaiho(Tokyo). 2025. 128. 1. 76-78
Masaya Kawaguchi, Hiroki Kato, Tatsuro Furui, Masanori Isobe, Yoshifumi Noda, Fuminori Hyodo, Tatsuhiko Miyazaki, Masayuki Matsuo. Prediction of grading of ovarian endometrioid carcinoma using conventional MRI features. Japanese journal of radiology. 2024
飯沼光司, 大澤華織, 伊藤裕基, 竹内慎一, 前川由佳, 堀江憲吾, 中根慶太, 加藤卓, 水谷晃輔, 土屋朋大, et al. Malignant peripheral nerve sheath tumorの1例. 泌尿器科紀要. 2024. 70. 12. 471-471
Masashi Kuroki, Hirofumi Shibata, Kazuhiro Kobayashi, Manato Matsubara, Saki Akita, Tatsuhiko Yamada, Rina Kato, Ryota Iinuma, Ryo Kawaura, Hiroshi Okuda, et al. Postoperative pathological findings and prognosis of early laryngeal and pharyngeal cancer treated with transoral surgery. Auris, nasus, larynx. 2024. 51. 6. 976-983

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MISC (210)：

小林一博, 酒々井夏子, 岩田浩明, 宮崎龍彦. VEXAS症候群の一例. 脈管学(Web). 2023. 63. 1
小林一博, 松本宗和, 佐々木健太, 中川篤, 酒々井夏子, 宮崎龍彦. 腋窩リンパ節生検で発見されたsecretory carcinomaの一例. 日本臨床細胞学会雑誌(Web). 2023. 62
花木建貴, 大江直行, 林大地, 遠渡沙緒理, 大久保貴史, 酒々井夏子, 加納清充, 小関道夫, 宮崎龍彦, 岩間亨. 小児髄芽腫治療後に小脳膠芽腫を来たした2例. 日本小児血液・がん学会雑誌(Web). 2023. 60. 1
山内知貴, 林大地, 安江志保, 遠渡沙緒理, 小関道夫, 大西秀典, 岩井正道, 遠渡純輝, 松本宗和, 酒々井夏子, et al. 16歳男性前縦隔胚細胞腫瘍. 日本小児血液・がん学会雑誌(Web). 2023. 60. 1
松田章秀, 大江直行, 大久保貴史, 小木曾衛, 今井直哉, 酒々井夏子, 宮崎龍彦, 岩間亨. Introduction of molecular pathological analysis of glioblastoma after cerebellar medulloblastoma treatment. 小児の脳神経(Web). 2023. 48. 1

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Books (21)：

組織細胞化学2021
中西印刷株式会社 2021
組織細胞化学2020
中西印刷株式会社 2020
組織細胞化学2019
学際企画 2019
組織細胞化学2018
日本組織細胞化学会 2018
血管炎(第2版)- 基礎と臨床のクロストーク -
日本臨床 2018

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Lectures and oral presentations (175)：

基底・扁平上皮癌の一例
(日本病理学会会誌 2022)
鼠径リンパ節の著明な腫脹を来たしたPTGC型IgG4関連疾患の1例
(日本病理学会会誌 2022)
診断に難渋したMesenchymal chondrosarcomaの1例
(日本病理学会会誌 2022)
組換え近交系マウス腎炎・腎血管炎治療モデルを用いた治療効果修飾遺伝因子の解析
(日本病理学会会誌 2022)
COVID-19感染を伴いドイツで死亡した患者94例の剖検腎解析
(日本病理学会会誌 2022)

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Education (1)：

- 1990 Ehime University Faculty of Medicine

Professional career (1)：

博士(医学) (愛媛大学)

Work history (12)：

2023/04 - 現在 Tokai National Higher Education and Research System
2022/01 - 現在 Gifu University Gifu University Hospital, Department of Pathology Professor
2022/01 - 2023/03 Tokai National Higher Education and Research System
2020/04 - 2021/12 Tokai National Higher Education and Research System
2013/10 - 2021/12 Gifu University Graduate School of Medicine Pathology Division, Gifu University Hospital Hospital Professor

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Committee career (13)：

2024/05 - 現在 Japanese Society of Pathology Principal of Chubu-divixion
2024/05 - 現在 Japanese Society of Pathology Director
2021/06 - 現在 Japanese Society of Clinical Cytology Medical Safety Comittee
2021/03 - 現在 Tokai Society of Clinical Cytology Principal
2020/04 - 現在 Japanese Society of Pathology Educational comittee

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Awards (1)：

2000/10 - Japanese Society of Pathology Case research award

Association Membership(s) (1)：

Japanese Society of Clinical Cytology

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