Suico Mary Ann

スイコメリーアン | Suico Mary Ann

Affiliation and department：
Job title： Research assistant
Homepage URL (1)： http://www.molmed730.org

Research field (2)： Pharmacology , Pharmaceuticals - health and biochemistry

Research theme for competitive and other funds (16)：

2023 - 2026 Therapeutic screening and molecular basis for Congenital Nephrotic Syndrome of the Finish type (CNF)
2022 - 2025 Advanced research on the original drug discovery platform for hereditary intractable Alport syndrome
2020 - 2023 Molecular basis on drug development targeting causative molecules of genetic nephritis Alport syndrome
2019 - 2022 Establishment of research platform for the development of renal precision medicine
2017 - 2020 Molecular basis and clinical implication of podocyte MEF-p53 network in CKD pathogenesis

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Papers (127)：

Yuimi Koyama, Mary Ann Suico, Aimi Owaki, Ryoichi Sato, Jun Kuwazuru, Shota Kaseda, Yuya Sannomiya, Jun Horizono, Kohei Omachi, Tomoko Horinouchi, et al. Trimerization profile of type IV collagen COL4A5 exon deletion in X-linked Alport syndrome. Clinical and Experimental Nephrology. 2024
Noriki Takahashi, Ryunosuke Nakashima, Aoi Nasu, Megumi Hayashi, Haruka Fujikawa, Taisei Kawakami, Yuka Eto, Tomoki Kishimoto, Ayami Fukuyama, Choyo Ogasawara, et al. T3 Intratracheal Therapy Alleviates Pulmonary Pathology in an Elastase-Induced Emphysema-Dominant COPD Mouse Model. Antioxidants (Basel, Switzerland). 2023. 13. 1
Jun Kuwazuru, Mary Ann Suico, Kohei Omachi, Haruka Kojima, Misato Kamura, Shota Kaseda, Teppei Kawahara, Yuki Hitora, Hikaru Kato, Sachiko Tsukamoto, et al. CyclosporinA derivative as therapeutic candidate for Alport syndrome by inducing mutant type IV collagen secretion. Kidney360. 2023. Publish Ahead of Print. 7. 909-917
Ryoko Sasaki, Mary Ann Suico, Keisuke Chosa, Yuriko Teranishi, Takashi Sato, Asuka Kagami, Shunsuke Kotani, Hikaru Kato, Yuki Hitora, Sachiko Tsukamoto, et al. Combinatorial screening for therapeutics in ATTRv amyloidosis identifies naphthoquinone analogues as TTR-selective amyloid disruptors. Journal of Pharmacological Sciences. 2023. 151. 1. 54-62
Keiko Ueno-Shuto, Shunsuke Kamei, Megumi Hayashi, Ayami Fukuyama, Yuji Uchida, Naofumi Tokutomi, Mary Ann Suico, Hirofumi Kai, Tsuyoshi Shuto. A Splice Switch in SIGIRR Causes a Defect of IL-37-Dependent Anti-Inflammatory Activity in Cystic Fibrosis Airway Epithelial Cells. International Journal of Molecular Sciences. 2022. 23. 14. 7748-7748

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MISC (265)：

小笠原長耀, 高橋宜暉, 林恵, 福島友太朗, 加世田将大, 岸本朋樹, 福山絢美, スイコ・メリーアン, 首藤剛, 甲斐広文. 細胞老化がCOPD病態関連因子ENaC発現に与える影響. 日本抗加齢医学会総会プログラム・抄録集. 2023. 23回. 267-267
福島友太朗, 後藤翔太郎, 鏡明日香, 園田洋孝, Suico Mary Ann, 甲斐広文, 首藤剛. 線虫の経時的画像解析評価系(C-HAS)を用いた健康寿命関連遺伝子W09D10.4/PPTC7の同定. 基礎老化研究. 2023. 47. 2. 80-80
小山結実, SUICO Mary Ann, 加世田将大, 桑水流淳, 三宮裕也, 堀園潤, 津波古遥希, 尾脇あいみ, 佐藤諒一, 白神正博, et al. Alport症候群原因遺伝子COL4A5の各種exon欠損がIV型コラーゲン三量体分泌に与える影響. 日本小児腎臓病学会雑誌(Web). 2023. 36
近藤龍也, 宮川展和, 北野さやか, 渡邊拓郎, 吉積臨太郎, MARY Ann Suico, 阪口雅司, 井形元維, 松村剛, 甲斐広文, et al. 熱ストレス応答経路の多臓器間クロストーク. 糖尿病(Web). 2023. 66. 5
首藤剛, 福島友太朗, 桑野雄平, 後藤翔太郎, 鏡明日香, 小澤享子, スイコ・メリーアン, 甲斐広文. 4象限集団解析法を用いたCエレガンス健康寿命に対する各種素材の影響. 日本抗加齢医学会総会プログラム・抄録集. 2022. 22回. 249-249

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Lectures and oral presentations (221)：

Elucidation and therapeutic application of a novel ameliorating mechanism for renal pathology with transient increase in proteinuria via Nrf2 activation
(日本薬学会年会要旨集(Web) 2024)
線虫の経時的画像解析評価系(C-HAS)を用いた健康寿命関連遺伝子W09D10.4/PPTC7の同定
(基礎老化研究 2023)
加齢に伴う野生型ATTRアミロイドーシス予防・進行抑制に資するザクロ由来のアミロイドブレイク活性成分の同定
(基礎老化研究 2023)
細胞老化がCOPD病態関連因子ENaC発現に与える影響
(基礎老化研究 2023)
加齢に伴う野生型ATTRアミロイドーシス予防・進行抑制に資するクロ由来のアミロイドブレイク活性成分の同定
(日本抗加齢医学会総会プログラム・抄録集 2023)

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Professional career (1)：

薬学博士 (熊本大学)

Awards (1)：

2015 - 日本薬理学会 Best Reviewer Award

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