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J-GLOBAL ID:200901092108462655   Update date: Feb. 21, 2025

Hideki Takai

タカイ ヒデキ | Hideki Takai
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Affiliation and department:
Job title: Assosiate Professor
Other affiliations (1):
  • Nihon University  School of Dentistry at Matsudo Department of Dentistry   Assosiate Professor
Research field  (1): Conservative dentistry and endodontics
Research keywords  (2): cell differentiation ,  Transcription Factors
Research theme for competitive and other funds  (9):
  • 2021 - 2024 miRNAを用いた転写因子制御による歯周組織関連細胞の分化誘導
  • 2020 - 2023 接合上皮発現タンパク質の発現制御による歯周病治療戦略
  • 2018 - 2021 Differentiation induction of periodontal tissue constituent cells by regulating expression of miRNA
  • 2017 - 2020 Strategy for prevention of periodontal disease by controlling protein expressions of junctional epithelium expressed proteins
  • 2015 - 2017 Analysis of transcription factors involved in the differentiation induction of periodontal tissue constituent cells
Show all
Papers (38):
  • Jin Z., Tsuruya Y., Igarashi K., Yamaguchi A., Takai H., Nakayama Y., Ogata Y. Transcriptional regulation of human follicular dendritic cell-secreted protein gene by interleukin-6. Odontology. 2025
  • Naomi Igarashi, Hideki Takai, Yorimasa Ogata. Effects of initial periodontal therapy on leucine-rich alpha-2 glycoprotein levels in saliva from Japanese patients with chronic periodontitis. Journal of Oral Science. 2025. 67. 1. 10-13
  • Hideki Takai, Naomi Igarashi, Yorimasa Ogata. TNF-α and IL-6 Regulate Leucine-rich α2 Glycoprotein and Heat Shock Protein 70 Levels in Human Gingival Epithelial Ca9 - 22 Cells. International Journal of Oral Medical Sciences. 2024. 23. 1. 26-32
  • Ryoma Nakao, Ayami Takatsuka, Kengo Mandokoro, Naoki Narisawa, Tsuyoshi Ikeda, Hideki Takai, Yorimasa Ogata. Multimodal inhibitory effect of matcha on Porphyromonas gingivalis. Microbiology Spectrum. 2024
  • Hidenobu Senpuku, Kazuhisa Yoshimura, Hideki Takai, Yutaka Maruoka, Erika Yamashita, Akira Tominaga, Yorimasa Ogata. Role of Macrophage Colony-Stimulating Factor for Staphylococcal Infection in the Oral Cavity. Journal of clinical medicine. 2023. 12. 18
more...
MISC (43):
  • Hideki Takai, Yorimasa Ogata. Possibility of differentiation and induction of periodontal tissue constituent cells by transcription factor regulation using miRNA. 日本歯周病学会会誌. 2022. 64. 2. 51-57
  • 両角 俊哉, 高柴 正悟, 三邉 正人, 野村 義明, 福田 光男, 花田 信弘, 角田 衣理加, 小林 宏明, 中村 利明, 中山 洋平, et al. 歯周病のポケット検査における代表歯・部位の選定. 日本口腔検査学会総会・学術大会プログラム・抄録集. 2021. 14回. 70-71
  • 両角 俊哉, 野村 義明, 福田 光男, 花田 信弘, 角田 衣理加, 小林 宏明, 三邉 正人, 中村 利明, 中山 洋平, 西村 英紀, et al. 歯周病評価における最適検査部位の選定 項目反応理論Graded response modelの応用. 日本歯周病学会会誌. 2021. 63. 春季特別. 106-106
  • 両角 俊哉, 野村 義明, 福田 光男, 花田 信弘, 角田 衣理加, 小林 宏明, 三邉 正人, 中村 利明, 中山 洋平, 西村 英紀, et al. 歯周病評価における最適検査部位の選定 項目反応理論Graded response modelの応用. 日本歯周病学会会誌. 2021. 63. 春季特別. 106-106
  • Mizuho Yamazaki-Takai, Hideki Takai, Yasunobu Iwai, Keisuke Noda, Masaru Mezawa, Yuto Tsuruya, Arisa Yamaguchi, Yohei Nakayama, Yorimasa Ogata. MiR-200b suppresses TNF-α-induced AMTN production in human gingival epithelial cells. Odontology. 2020. 109. 2. 403-410
more...
Books (3):
  • 聞くに聞けない歯周病治療100
    株式会社デンタルダイヤモンド社 2018
  • 歯周外科 見て学んで始めるガイド 歯周基本治療から手技習得のポイント、術後のケアまで
    クインテッセンス出版株式会社 2017
  • 細胞を用いた歯周組織再生療法
    歯界展望・Vol. 118 No.5 2011
Lectures and oral presentations  (62):
  • miR-200a suppresses Twist2 and induces differentiation of gingival fibroblasts into osteogenic cells
    (2024)
  • IL-1β刺激により歯肉線維芽細胞から分泌されたエクソソーム中のmiRNAによる骨芽細胞関連転写因子の抑制
    (第66回春季日本歯周病学会 2023)
  • Induction of osteogenic cells from human gingival fibroblasts by inhibition of transcription factors highly expressed in gingival fibroblasts
    (第64回秋季日本歯周病学会 2021)
  • Trial of clinical guideline formulation using GRADE approach 1 Is the oral antimicrobial therapy effective in surgical procedure for peri-implantitis ?
    (第63回春季日本歯周病学会 2020)
  • Anti-heat shock protein 70 levels in gingival crevicular fluid of Japanese chronic periodontitis patients
    (The 59th General Session of Korean Academy of Periodontology 2019)
more...
Education (2):
  • - 2007 Nihon University Graduate School Graduate School, Division of Dental Research Dentistry
  • - 2003 Nihon University School of Dentistry Department of Dentistry
Work history (3):
  • 2020/10 - 現在 School of Dentistry at Matsudo,Nihon University Department of periodontology Associate professor
  • 2015/04 - 2020/09 School of Dentistry at Matsudo,Nihon University Department of periodontology Instructor
  • 2009/04 - 2014/03 School of Dentistry at Matsudo,Nihon University Department of periodontology Assistant Professor
Committee career (3):
  • 2021/04 - 現在 日本歯周病学会 医療委員会
  • 2021/04 - 現在 日本歯周病学会 専門委員会
  • 2015/04 - 2021/03 日本歯周病学会 用語委員会
Awards (2):
  • 2008 - 日本歯科保存学会奨励賞
  • 2008 - 日本歯周病学会会誌賞
Association Membership(s) (3):
臨床歯周病学会 ,  日本歯周病学会 ,  日本保存学会
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