Rchr
J-GLOBAL ID：200901092573853300   Update date: Nov. 15, 2024

OYAMA Fumitaka

オヤマ フミタカ | OYAMA Fumitaka
Affiliation and department：
Kogakuin University School of Advanced Engineering Department of Chemistry and Life Science

About Kogakuin University School of Advanced Engineering Department of Chemistry and Life Science


Job title： Professor
Homepage URL  (1)： http://www.ns.kogakuin.ac.jp/~wwa1074/index.html
Research field  (6)： Laboratory animal science ,  Neuroanatomy and physiology ,  Pathobiochemistry ,  Biochemistry ,  Applied biochemistry ,  Genetics
Research keywords  (14)： gene expression in cancerous tissues ,  Huntington disease ,  Alzheimer's disease ,  Enzyme strucutr-function relationship ,  Chitin・chitosan ,  allergy and asthma ,  Disease-related genes ,  ほ乳類キチナーゼ ,  キチン含有生物の動物食糧への利用 ,  キチン・キトサン ,  ヒトの疾患に関係する遺伝子 ,  firefly luciferase ,  Enzyme strucutr-function relationship ,  allergy and asthma
Research theme for competitive and other funds  (27)：
  • 2023 - 2026 Evolution of structure and function of acid chitinase (Chia): Promoting its use in livestock feed for insects
  • 2016 - 2019 Is acidic mammalian chitinase a major glycosidase in the stomachs of mouse and porcine?
  • 2009 - 2019 Studies on the structure and function relationships of proteins using the biotechnological methods
  • 2009 - 2019 Application of animal biomass for medical and pharmacological areas
  • 2009 - 2019 Development of novel methods for isolation and characterization of cells and nucleic acids
Show all
Papers (54)：
  • Suzuki, K., Okawa, K., Ohkura, M., Kanaizumi, T., Kobayashi, T., et al. Evolutionary insights into sequence modifications governing chitin recognition and chitinase inactivity in YKL-40 (HC-gp39, CHI3L1). J. Biol. Chem. 2024. in press
  • Tabata, E., Kobayashi, I., Morikawa, T., Kashimura, A., Bauer, P.O. and <U>Oyama, et al. Evolutionary activation of acidic chitinase in herbivores through the H128R mutation in ruminant livestock. iScience. 2023. 26. 107254
  • Kazuaki Okawa, Eri Tabata, Yuta Kida, Kyohei Uno, Hidetoshi Suzuki, Minori Kamaya, Peter O. Bauer, Fumitaka Oyama. Irreversible evolutionary loss of chitin-degrading ability in the chitinase-like protein Ym1 under positive selection in rodents. Protein Science. 2023
  • Daisuke Yamanaka, Kento Suzuki, Masahiro Kimura, Fumitaka Oyama, Yoshiyuki Adachi. Functionally modified chitotriosidase catalytic domain for chitin detection based on split-luciferase complementation. Carbohydrate polymers. 2022. 282. 119125-119125
  • Uehara, M., Takasaki, C., Wakita, S., Sugahara, Y., Tabata, E., et al. Crab-eating monkey acidic chitinase (CHIA) efficiently degrades chitin and chitosan under acidic and high-temperature conditions. Molecules. 2022. 27. 409
ｍore...
MISC (106)：
  • Haruko Miyazaki, Tomoyuki Yamanaka, Fumitaka Oyama, Yoshihiro Kino, Masaru Kurosawa, Mizuki Yamada-Kurosawa, Risa Yamano, Tomomi Shimogori, Nobutaka Hattori, Nobuyuki Nukina. FACS-array-based cell purification yields a specific transcriptome of striatal medium spiny neurons in a murine Huntington disease model. Journal of Biological Chemistry. 2020. 295. 29. 9768-9785
  • 田畑絵理, 田畑絵理, 樫村明徳, 上原麻衣子, 脇田悟誌, 菅原康里, 圦本晃海, 佐々木えりか, 小山文隆. Gene expression analysis and enzyme function of acidic chitinase in common marmoset. 日本農芸化学会大会講演要旨集(Web). 2020. 2020
  • 大野 美紗, 宮崎 雅雄, 木村 将大, 坂口 政吉, 小山 文隆, 山下 哲郎. マウスにおけるジ-N-アセチルキトビアーゼの発現解析と酵素の性質解析. 日本生化学会大会プログラム・講演要旨集. 2019. 92回. [2T17a-03]
  • 田畑絵理, 田畑絵理, 樫村明徳, 上原麻衣子, 脇田悟誌, 菅原康里, 圦本晃海, 佐々木えりか, 小山文隆. Common marmoset (Callithrix jacchus), an insectivorous nonhuman primate, predominantly expresses acidic chitinase, which can digest insect chitin in stomach. キチン・キトサン研究. 2019. 25. 2
  • Masayoshi Sakaguchi, Yudai Matsushima, Toshiyuki Nankumo, Junichi Seino, Satoshi Miyakawa, Shotaro Honda, Yasusato Sugahara, Fumitaka Oyama, Masao Kawakita. Glucoamylase of Caulobacter crescentus CB15: cloning and expression in Escherichia coli and functional identification. AMB EXPRESS. 2014. 4. 5
ｍore...
Patents (1)：
  • アルツハイマー病モデル動物
Books (17)：
  • ß -アミロイドと PHF 広川ニューロサイエンス 3 新しい神経伝達研究法 II 2. 生化学的研究法 2.2. 細胞膜、物質レベルの研究
    広川書店 2000
  • タウの分解機構
    Dementia Japan 日本認知症学会 1999
  • Update article: Chloroquine myopathy suggests that tau is degraded in lysosomes : implication for the formation of paired helical filaments in Alzheimer’s disease.
    Neurosci. Res. Elsevier 1998
  • Nonneural tau: transient upregulation and subsequent accumulation of big and small tau in chloroquine myopathy.
    In Alzheimer's Disease: Biology, Diagnosis and Therapeutics (ed. by Iqbal et al.) 1997
  • クロロキンミオパチーラット
    内科 1996
ｍore...
Lectures and oral presentations  (220)：
  • Enhancing the activity of YKL-39: investigating mutations and enzymatic properties
    (Annual Meeting of the American Society of Human Genetics (ASHG) 2024)
  • Engineering chimeric and mutant chitinase proteins to uncover the underlying mechanisms of decreased acidic chitinase activity in herbivorous animals
    (Engineering recombinant proteins for structural and functional studies 2023 2023)
  • Multiple sequence modifications result in loss of chitinolytic activity in YKL-40.
    (Annual Meeting of the American Society of Human Genetics (ASHG) 2023)
  • Structure and function of mammalian chitinases: Insights from chimeric analysis
    (Annual Meeting of the American Society of Human Genetics (ASHG) 2023)
  • 反芻動物の酸性キチナーゼの活性化
    (第37回日本キチン・キトサン学会大会 2023)
ｍore...
Works (5)：
  • Characterization of crab-eating monkey acidic chitinase: Robust chitinolytic activity and its application
    Maiko Uehara and Fumitaka Oyama 2022 - 2022
  • Tau dynamics in chloroquine myopathy suggests that tau is degraded in lysosomes in muscle」
    Fumitaka Oyama, Nobuyuki Murakami, Yongjun Gu, Ikuya Nonaka, and Yasuo Ihara 1997 - 1997
  • 非神経系の tau の動態:アルツハイマー病モデルとしてのクロロキンミオパチーでの解析
    小山文隆、顧擁軍、村上信行、埜中征哉、井原康夫 1996 - 1996
  • Alternative Splicing of fibronectin pre-mRNA in Human Tissues
    Fumitaka Oyama 1992 - 1992
  • 逆転写酵素の DNA-polymerase 活性とRNase H 活性の逆転写過程における作用機作
    小山文隆 1992 - 1992
Education (3)：
  • 1982 - 1985 Tohoku University Graduate School of Agricultural Science Agricultural Chemistry Program
  • 1980 - 1982 Tohoku University Graduate School of Agricultural Science Agricultural Chemistry Program
  • 1976 - 1980 Ibaraki University Faculty of Agriculture Department of Agricultural Chemistry
Professional career (3)：
  • BS (Ibaraki University)
  • M.S. (Agricultural Chemistry) (Tohoku University)
  • Ph.D. (Agricultural Chemistry) (Tohoku University)
Work history (18)：
  • 2015/04 - 現在 Kogakuin University School of Advanced Engineering, Department of Chemistry and Life Science
  • 2009 - 現在 Professor, Biotechnology Laboratory, Department of Applied Chemistry, Faculty of Engineering, Kogakuin University
  • 2019/04 - 2020/03 京都大学霊長類研究所 非常勤講師
  • 2009 - 2015/03 Kogakuin University Faculty of Engineering, Department of Applied Chemistry
  • 2012/04 - 工学院大学大学院工学研究科博士後期課程化学応用学専攻担当
Show all
Committee career (5)：
  • 2018/08 - 2019/08 Board member the Japanese Society for Chitin and Chitosan
  • 2014/01 - 2016/08 Japanese Society for Chitin and Chitosan Board of directors
  • 2014/01 - 2014/12 Board of directors, the Japanese Society for Chitin and Chitosan
  • 2011/01 - 2013/12 Japanese Society for Chitin and Chitosan Board member
  • 2011/01 - 2013/12 Board of the Japanese Society for Chitin and Chitosan
Association Membership(s) (5)：
Japanese Society for Chitin and Chitosan ,  American Society of Human Genetics ,  JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY ,  American Society of Human Genetics ,  Japanese Society for Chitin and Chitosan
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page

TOP

BOTTOM