Rchr
J-GLOBAL ID:200901092926124994
Update date: Dec. 05, 2024
Matsumoto Takayuki
マツモト タカユキ | Matsumoto Takayuki
Affiliation and department:
Research field (1):
Pharmacology
Research keywords (29):
extracellular nucleotides
, 糖尿病
, 血管内皮細胞
, インスリン
, 細小血管障害
, 血管内皮由来収縮因子
, 内皮由来因子
, 酸化ストレス
, EDHF
, エンドセリン
, 血管機能障害
, 内皮機能障害
, AGE
, CML
, 血管平滑筋細胞
, 薬物治療
, 糖尿病性血管機能障害
, 血管内皮由来過分極因子
, 循環
, 遺伝子発現
, インスリン抵抗性
, エンドセリン-1
, 活性酸素
, PPARα
, アディポサイトカイン
, 内皮細胞
, cyclic AMP
, NAD(P)Hoxidase
, 糖尿病性血管合併症
Research theme for competitive and other funds (8):
- 2018 - 2021 Relationship between advanced glycation endproducts and chronic inflammation in diabetic vasculopathy
- 2014 - 2016 Investigation of molecular basis in diabetes-associated vascular endothelial dysfunction and sex differences under chronic inflammation
- 2012 - 2013 Pathophysiological role of uridine adenosine tetraphosphate in diabetic vasculopathy
- 2009 - 2010 糖尿病性細小血管障害における内皮由来過分極因子シグナルに対するAGEの影響
- 2007 - 2008 Mechanisms underlying the insulin-induced impairment of microvascular functions in diabetic state.
- 2005 - 2006 糖尿病性細小血管障害におけるアディポサイトカインの関与
- 2002 - 2003 Adipocytokine-related genes and insulin resistance
- 糖尿病性血管合併症の研究
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Papers (179):
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Kumiko Taguchi, Hiroyuki Kondo, Takayuki Matsumoto, Tsuneo Kobayashi. Effect of esaxerenone on the onset of aortic endothelial dysfunction and circulating microparticles in type 1 diabetic male mice. Scientific Reports. 2024. 14. 1
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Takayuki Matsumoto, Takayuki Nagano, Atsuko Yokota, Eisaku Nakamura, Masachika Kuwabara, Ryuichi Yamamoto, Naoko Tanaka-Totoribe. Differential Suppressive Effects of Rho Kinase Inhibitor Fasudil on Serotonin- and Noradrenaline-Induced Contractions of Human Internal Thoracic Arteries and Saphenous Veins. Biological and Pharmaceutical Bulletin. 2024. 47. 10. 1657-1661
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Takayuki Matsumoto, Takayuki Nagano, Kumiko Taguchi, Tsuneo Kobayashi, Naoko Tanaka-Totoribe. Toll-like receptor 3 involvement in vascular function. European Journal of Pharmacology. 2024. 979. 176842-176842
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Takayuki Matsumoto, Kumiko Taguchi, Tsuneo Kobayashi. Role of TRPV4 on vascular tone regulation in pathophysiological states. European Journal of Pharmacology. 2023. 959. 176104-176104
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Takayuki Matsumoto, Tomoe Osada, Kumiko Taguchi, Tsuneo Kobayashi. Endothelial Dysfunction in Superior Mesenteric Arteries Isolated from Adenine-Induced Renal Failure in Model Rats. Biological and Pharmaceutical Bulletin. 2023. 46. 8. 1156-1160
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MISC (100):
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Zhichao Zhou, Takayuki Matsumoto. A 15-Year Study on Up4A in Cardiovascular Disease. Frontiers in Pharmacology. 2020. 11
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Trevor Hardigan, Kathryn Spitler, Takayuki Matsumoto, Maria Alicia Carrillo-Sepulveda. Activation of Toll-like receptor 3 increases mouse aortic vascular smooth muscle cell contractility through ERK1/2 pathway (vol 467, pg 2375, 2015). PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. 2015. 467. 11. 2387-2387
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Styliani Goulopoulou, Johanna Hannan, Takayuki Matsumoto, Adviye Ergul, R. Clinton Webb. Reduced Relaxation Responses to Heme-dependent and -independent Soluble Guanylyl Cyclase Activation in Mesenteric Arteries of a Rat Model of Type 2 Diabetes. FASEB JOURNAL. 2015. 29
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Cameron G. McCarthy, Camilla F. Wenceslau, Styliani Goulopoulou, Safia Ogbi, Takayuki Matsumoto, R. Clinton Webb. Chloroquine, an Inhibitor of Endosomal Toll-like Receptors, Improves Blood Pressure and Endothelial Function in Spontaneously Hypertensive Rats. HYPERTENSION. 2014. 64
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Styliani Goulopoulou, Takayuki Matsumoto, Camilla F. Wenceslau, Cameron G. McCarthy, Kathryn Spitler, R. Clinton Webb. Toll-Like Receptor 9 Activation Potentiates Uterine Artery Responsiveness to Thromboxane A(2) Via Cyclooxygenase-Dependent Mechanisms in Pregnant Rats. REPRODUCTIVE SCIENCES. 2014. 21. 3. 101A-101A
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Lectures and oral presentations (422):
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Esaxerenoneはmicroparticles産生を減少させることで糖尿病性血管内皮機能障害を抑制した
(第148回 日本薬理学会関東部会 2023)
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Carvedilolが糖尿病性血管内皮機能障害を改善するメカニズムの解析
(第148回 日本薬理学会関東部会 2023)
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Spontaneously hypertensive rat 摘出頸動脈における 5-HT 収縮反応に対する TRPC3 チャネルの関与
(第148回 日本薬理学会関東部会 2023)
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自然発症高血圧ラット上腸間膜動脈におけるウリジン三リン酸誘発弛緩反応と内皮由来因子の関わり
(第148回 日本薬理学会関東部会 2023)
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Streptozotocin-induced diabetic rat femoral arteryにおける uridine diphosphate 誘発収縮反応
(第148回 日本薬理学会関東部会 2023)
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Professional career (1):
Work history (7):
- 2024/04 - 現在 Kyushu University of Medical Science
- 2023/04 - 2024/03 Hoshi University Hoshi University
- 2018/01 - 2023/03 Hoshi University Hoshi University
- 2013/04 - 2017/12 Hoshi University Hoshi University
- 2007/04 - 2013/03 Hoshi University Hoshi University
- 2010/04 - 2011/09 Medical College of Georgia (Augusta University) Department of Physiology Visiting Assistant Professor
- 2003/04 - 2007/03 Hoshi University Hoshi University
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Committee career (3):
- 2021/08 - 現在 日本平滑筋学会 日本平滑筋学会評議員
- 2011/09 - 現在 American Heart Association Fellow of American Heart Association (FAHA)
- 2009 - 現在 日本薬理学会 日本薬理学会学術評議員
Awards (8):
- 2024/03 - 日本薬理学会 JPS優秀査読者賞
- 2021/08 - Tsuneo Shiratori Award
- 2019/11 - 日本循環薬理学会 第29回日本循環薬理学会 第55回高血圧関連疾患モデル学会 Poster Award
- 2013 - 日本平滑筋学会 第55回日本平滑筋学会総会 優秀演題賞
- 2012/04 - The American Physiological Society The 2012 International Early Career Physiologist Travel Award
- 2010/10 - The American Heart Association The Harry Goldblatt New Investigator Award Finalist
- 2009 - 日本薬学会関東支部 平成21年度日本薬学会関東支部奨励賞 糖尿病性血管合併症における内皮由来過分極因子の重要性と治療戦略へのアプローチ
- 2007 - Hirosi Kuriyama Award Mechanisms underlying the chronic pioglitazone treatment-induced improvement in the impaired endothelium-dependent relaxation seen in aortas from diabetic rats.
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Association Membership(s) (6):
The American Physiological Society
, The American Heart Association
, 日本薬学会
, 日本平滑筋学会
, 日本循環薬理学会
, 日本薬理学会
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