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J-GLOBAL ID：200901094384839528 Update date: Dec. 31, 2024

Kuroda Etsushi

クロダエツシ | Kuroda Etsushi

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Affiliation and department：
Job title： Professor and chairman
Homepage URL (1)： https://www.hyo-med.ac.jp/department/immunology/

Research field (1)： Immunology

Research keywords (2)：免疫学 , Immunology

Research theme for competitive and other funds (19)：

2024 - 2027 Assessing the risk of lung cancer development and malignant transformation caused by PM2.5, as well as elucidating its mechanism of action
2023 - 2026 Analysis of pathogenic alveolar macrophages which release IL-1alpha in response to fine particles.
2020 - 2023 環境化学物質による眼免疫活性化を介した新規アレルギー性炎症発症機構の解析
2017 - 2020 免疫制御可能な機能性ペプチドの網羅的創製と創薬展開
2017 - 2019 Analysis of allergic inflammation triggered by eyes.

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Papers (126)：

Tatsuo Ueda, Takumi Adachi, Tomoya Hayashi, Koubun Yasuda, Kazufumi Matsushita, Eiko Koike, Rie Yanagisawa, Takahiro Nagatake, Jun Kunisawa, Ken J. Ishii, et al. Bisphenol A triggers activation of ocular immune system and aggravates allergic airway inflammation. Clinical Immunology. 2024. 268. 110370-110370
Izumi Sasaki, Yuri Fukuda-Ohta, Chihiro Nakai, Naoko Wakaki-Nishiyama, Chizuyo Okamoto, Daisuke Okuzaki, Shuhei Morita, Shiori Kaji, Yuki Furuta, Hiroaki Hemmi, et al. A stress sensor, IRE1α, is required for bacterial-exotoxin-induced interleukin-1β production in tissue-resident macrophages. Cell Reports. 2024. 43. 4. 113981-113981
Dasen Ye, Akio Miyoshi, Tomoe Ushitani, Manabu Kadoya, Masataka Igeta, Kosuke Konishi, Takuhito Shoji, Koubun Yasuda, Shiho Kitaoka, Hideshi Yagi, et al. RAGE in circulating immune cells is fundamental for hippocampal inflammation and cognitive decline in a mouse model of latent chronic inflammation. Brain, behavior, and immunity. 2024. 116. 329-348
Burcu Temizoz, Takayuki Shibahara, Kou Hioki, Tomoya Hayashi, Kouji Kobiyama, Michelle Sue Jann Lee, Naz Surucu, Erdal Sag, Atsushi Kumanogoh, Masahiro Yamamoto, et al. 5,6-dimethylxanthenone-4-acetic acid (DMXAA), a partial STING agonist, competes for human STING activation. Frontiers in immunology. 2024. 15. 1353336-1353336
Izumi Sasaki, Yuri Fukuda-Ohta, Chihiro Nakai, Naoko Wakaki-Nishiyama, Chizuyo Okamoto, Takashi Orimo, Daisuke Okuzaki, Shuhei Morita, Shiori Kaji, Yuki Furuta, et al. A stress sensor IRE1α is required for bacterial exotoxin-induced inflammasome activation in tissue-resident macrophages. bioRxiv. 2023

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MISC (65)：

三好晶雄, 叶大森, 牛谷友栄, 角谷学, 小西康輔, 庄司拓仁, 安田好文, 黒田悦史, 北岡志保, 八木秀司, et al. 終末糖化産物受容体(RAGE)はメタボリックシンドロームにおける認知機能障害の病態に関与する. 日本内分泌学会雑誌. 2023. 99. 1. 383-383
叶大森, 三好晶雄, 牛谷友栄, 角谷学, 小西康輔, 庄司拓仁, 北岡志保, 黒田悦史, 八木秀司, 山本靖彦, et al. esRAGEによって潜在的な慢性炎症による認知障害は回復する(esRAGE can rescue cognitive impairment due to latent chronic inflammation). 糖尿病. 2023. 66. 4. 273-273
Patrick M. Lelliott, Masatoshi Momota, Michelle S. J. Lee, Etsushi Kuroda, Norifumi Iijima, Ken J. Ishii, Cevayir Coban. Applying imaging flow cytometry for the characterization and quantification of NETosis and cell death in vitro and in vivo. CELL DEATH DISCOVERY. 2019. 5
黒田悦史, 黒田悦史, 黒田悦史, 石井健, 石井健. アレルギー研究最前線基礎研究の最前線 II:上皮細胞,炎症細胞など微細粒子吸入とアレルギー性炎症. 医学のあゆみ. 2018. 265. 9. 779-784-784
黒田悦史, 黒田悦史, 黒田悦史, 小張真吾, 日下部峻斗, 日下部峻斗, 石井健, 石井健. 血管炎とアレルギー疾患-内因性・外因性アジュバントの関わり-I.微細粒子によるIL-1誘導とアレルギー性炎症. アレルギー・免疫. 2018. 25. 6. 740-747-747

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Patents (2)：

Education (5)：

- 2001 University of Occupational and Environmental Health, Japan
- 2001 University of Occupational and Environmental Health, Japan Graduate School, Division of Medicine
- 1997 Hiroshima University
- 1995 Kyushu Institute of Technology School of Computer Science and Systems Engineering
- 1995 Kyushu Institute of Technology Faculty of Computer Science and Systems Engineering

Professional career (2)：

Ph.D. (University of Occupational and Environmental Health, Japan)
M. Pharm. (Hiroshima University)

Awards (8)：

2017/06 - 第66回日本アレルギー学会学術大会 English session Best presentation award
2016/12 - 第45回日本免疫学会学術集会 Best presentation award
2015/09 - 日本免疫毒性学会奨励賞
2015/05 - 第64回日本アレルギー学会学術大会 English session Best presentation award
2010/09 - 第17回日本免疫毒性学会学術大会年会長賞

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Association Membership(s) (6)：

日本インターフェロン・サイトカイン学会 , 日本免疫毒性学会 , THE JAPANESE SOCIETY OF TOXICOLOGY , 日本アレルギー学会 , 日本寄生虫学会 , 日本免疫学会

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