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J-GLOBAL ID：200901095039341173   Update date: Mar. 21, 2025

TSUNO Yusuke

ツノ ユウスケ | TSUNO Yusuke
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Affiliation and department：
Kanazawa University Institute of Medical,Pharmaceutical and Health Sciences Faculty of Medicine

About Kanazawa University Institute of Medical,Pharmaceutical and Health Sciences Faculty of Medicine


Job title： Assistant Professor
Research field  (3)： Neuroscience - general ,  Clinical pharmacy ,  Physiology
Research keywords  (10)： Neuroscience ,  Circadian Rhythm ,  Sleep ,  Calcium Imaging ,  Electrophysiology ,  Neuromodulation ,  Acetylcholine ,  Learning ,  Memory ,  Olfaction
Research theme for competitive and other funds  (7)：
  • 2024 - 2027 Analysis of neural circuit activity related to promoting behavioral flexibility for establishing rehabilitation techniques
  • 2023 - 2026 Elucidation of circadian rhythm mechanisms using cell type-specific photometry
  • 2020 - 2023 In vivo analysis of suprachiasmatic nucleus AVP neurons using multiple type sensors
  • 2019 - 2020 Temporal and mechanistic signature of cholinergic dysfunction underlying fast versus slow cognitive decline in aging
  • 2018 - 2020 Cell-type specific calcium imaging of suprachiasmatic nucleus with fiber photometry
Show all
Papers (17)：
  • Yusuke Tsuno, Michihiro Mieda. Circadian rhythm mechanism in the suprachiasmatic nucleus and its relation to the olfactory system. Frontiers in Neural Circuits. 2024. 18. 1385908-1385908
  • Kaito Onodera, Yusuke Tsuno, Yuichi Hiraoka, Kohichi Tanaka, Takashi Maejima, Michihiro Mieda. In vivo recording of the circadian calcium rhythm in Prokineticin 2 neurons of the suprachiasmatic nucleus. Scientific Reports. 2023. 13. 1. 16974-16974
  • Yusuke Tsuno, Yubo Peng, Shin-ichi Horike, Mohan Wang, Ayako Matsui, Kanato Yamagata, Mizuki Sugiyama, Takahiro J. Nakamura, Takiko Daikoku, Takashi Maejima, et al. In vivo recording of suprachiasmatic nucleus dynamics reveals a dominant role of arginine vasopressin neurons in circadian pacesetting. PLOS Biology. 2023. 21. 8. e3002281
  • Md Tarikul Islam, Florian Rumpf, Yusuke Tsuno, Shota Kodani, Takeshi Sakurai, Ayako Matsui, Takashi Maejima, Michihiro Mieda. Vasopressin neurons in the paraventricular hypothalamus promote wakefulness via lateral hypothalamic orexin neurons. Current Biology. 2022. 32. 18. 3871-3885.e4
  • Yubo Peng, Yusuke Tsuno, Ayako Matsui, Yuichi Hiraoka, Kohichi Tanaka, Shin-Ichi Horike, Takiko Daikoku, Michihiro Mieda. Cell Type-Specific Genetic Manipulation and Impaired Circadian Rhythms in Vip tTA Knock-In Mice. Frontiers in Physiology. 2022. 13. 895633-895633
ｍore...
Lectures and oral presentations  (4)：
  • In vivo fiber photometry to reveal AVP neuronal function of the suprachiasmatic nucleus via cell-type specific labeling strategy
    (The 19th Environmental Physiology Pre-Congress 2025)
  • Suprachiasmatic nucleus AVP neurons alter VIP neuronal Ca<sup>2+</sup> activity and locomotor activity rhythms
    (NEURO2024, The 47th Annual Meeting of the Japan Neuroscience Society 2024)
  • In vivo analysis of suprachiasmatic nucleus circadian rhythm using neuronal cell type-specific knockout mice
    (Joint Congress of the 45th Annual Meeting of Japanese Society of Sleep Research, the 30th Annual Meeting of Japanese Society for Chronobiology 2023)
  • In vivo recording of the suprachiasmatic nucleus dynamics reveals a dominant role of arginine vasopressin neurons in the circadian pacesetting
    (The 17th Environmental Physiology Pre-Congress 2023)
Education (3)：
  • 2005 - 2009 The University of Tokyo Graduate School of Medicine Ph.D., Functional Biology
  • 2003 - 2005 The University of Tokyo Graduate School of Medicine M.S., Medical Sciences
  • 1999 - 2003 The University of Tokyo Faculty of Pharmaceutical Sciences B.S.
Professional career (1)：
  • Ph.D. (The University of Tokyo)
Work history (4)：
  • 2018/04 - 現在 Kanazawa University Graduate School of Medicine Assistant Professor
  • 2015/09 - 2018/03 University of Utah Department of Neurobiology and Anatomy Postdoctoral Fellow
  • 2010/01 - 2015/08 Boston University Department of Psychological and Brain Sciences Postdoctoral Associate
  • 2009/04 - 2009/12 Boston University Department of Biology Research Associate
Awards (2)：
  • 2020/10 - National Academy of Medicine, Japan Agency for Medical Research and Development Healthy Longevity Global Grand Challenge Catalyst Award Cholinergic Input in Fast Versus Slow Cognitive Decline Upon Aging
  • 2011/06 - Japan Society for the Promotion of Science Travel Grant for Attending Lindau Meetings
Association Membership(s) (4)：
THE JAPAN NEUROSCIENCE SOCIETY ,  SOCIETY FOR NEUROSCIENCE ,  JAPANESE SOCIETY FOR CHRONOBIOLOGY ,  THE PHYSIOLOGICAL SOCIETY OF JAPAN
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