TSUNO Yusuke

ツノユウスケ | TSUNO Yusuke

Affiliation and department：
Job title： Assistant Professor

Research field (3)： Neuroscience - general , Clinical pharmacy , Physiology

Research keywords (10)： Neuroscience , Circadian Rhythm , Sleep , Calcium Imaging , Electrophysiology , Neuromodulation , Acetylcholine , Learning , Memory , Olfaction

Research theme for competitive and other funds (7)：

2024 - 2027 Analysis of neural circuit activity related to promoting behavioral flexibility for establishing rehabilitation techniques
2023 - 2026 Elucidation of circadian rhythm mechanisms using cell type-specific photometry
2020 - 2023 In vivo analysis of suprachiasmatic nucleus AVP neurons using multiple type sensors
2019 - 2020 Temporal and mechanistic signature of cholinergic dysfunction underlying fast versus slow cognitive decline in aging
2018 - 2020 Cell-type specific calcium imaging of suprachiasmatic nucleus with fiber photometry

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Papers (17)：

Yusuke Tsuno, Michihiro Mieda. Circadian rhythm mechanism in the suprachiasmatic nucleus and its relation to the olfactory system. Frontiers in neural circuits. 2024. 18. 1385908-1385908
Kaito Onodera, Yusuke Tsuno, Yuichi Hiraoka, Kohichi Tanaka, Takashi Maejima, Michihiro Mieda. In vivo recording of the circadian calcium rhythm in Prokineticin 2 neurons of the suprachiasmatic nucleus. Scientific Reports. 2023. 13. 1. 16974-16974
Yusuke Tsuno, Yubo Peng, Shin-ichi Horike, Mohan Wang, Ayako Matsui, Kanato Yamagata, Mizuki Sugiyama, Takahiro J. Nakamura, Takiko Daikoku, Takashi Maejima, et al. In vivo recording of suprachiasmatic nucleus dynamics reveals a dominant role of arginine vasopressin neurons in circadian pacesetting. PLOS Biology. 2023. 21. 8. e3002281
Md Tarikul Islam, Florian Rumpf, Yusuke Tsuno, Shota Kodani, Takeshi Sakurai, Ayako Matsui, Takashi Maejima, Michihiro Mieda. Vasopressin neurons in the paraventricular hypothalamus promote wakefulness via lateral hypothalamic orexin neurons. Current Biology. 2022. 32. 18. 3871-3885.e4
Yubo Peng, Yusuke Tsuno, Ayako Matsui, Yuichi Hiraoka, Kohichi Tanaka, Shin-Ichi Horike, Takiko Daikoku, Michihiro Mieda. Cell Type-Specific Genetic Manipulation and Impaired Circadian Rhythms in Vip tTA Knock-In Mice. Frontiers in Physiology. 2022. 13. 895633-895633

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Lectures and oral presentations (2)：

Suprachiasmatic nucleus AVP neurons alter VIP neuronal Ca<sup>2+</sup> activity and locomotor activity rhythms
(NEURO2024, The 47th Annual Meeting of the Japan Neuroscience Society 2024)
In vivo analysis of suprachiasmatic nucleus circadian rhythm using neuronal cell type-specific knockout mice
(Joint Congress of the 45th Annual Meeting of Japanese Society of Sleep Research, the 30th Annual Meeting of Japanese Society for Chronobiology 2023)

Education (3)：

2005 - 2009 The University of Tokyo Graduate School of Medicine Ph.D., Functional Biology
2003 - 2005 The University of Tokyo Graduate School of Medicine M.S., Medical Sciences
1999 - 2003 The University of Tokyo Faculty of Pharmaceutical Sciences B.S.

Professional career (1)：

Ph.D. (The University of Tokyo)

Work history (4)：

2018/04 - 現在 Kanazawa University Graduate School of Medicine Assistant Professor
2015/09 - 2018/03 University of Utah Department of Neurobiology and Anatomy Postdoctoral Fellow
2010/01 - 2015/08 Boston University Department of Psychological and Brain Sciences Postdoctoral Associate
2009/04 - 2009/12 Boston University Department of Biology Research Associate

Awards (1)：

2011/06 - Japan Society for the Promotion of Science Travel Grant for Attending Lindau Meetings

Association Membership(s) (4)：

THE JAPAN NEUROSCIENCE SOCIETY , SOCIETY FOR NEUROSCIENCE , JAPANESE SOCIETY FOR CHRONOBIOLOGY , THE PHYSIOLOGICAL SOCIETY OF JAPAN

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