Rchr
J-GLOBAL ID:200901096028183262
Update date: Feb. 01, 2024 Hiroi Miki
ヒロイ ミキ | Hiroi Miki
Affiliation and department: Job title:
research associate
Research field (2):
Oral medicine (pathology)
, Oral medicine
Research keywords (14):
転写制御
, 情報伝達
, ケモカイン
, サイトカイン
, 遺伝子発現
, 炎症
, 免疫
, Transcriptional regulation
, Signal transduction
, Chemokine
, Cytokine
, Gene expression
, Inflammation
, Immunology
Research theme for competitive and other funds (9): - 2020 - 2023 Inactivation of IFN-induced chemokines by DPP4 and its clinical significance in oral cancer
- 2019 - 2022 口腔癌のインターフェロン耐性機構の解明と免疫エピゲノム併用療法の有効性の検討
- 2017 - 2020 Culture induction mechanism of tumor-associated macrophage and functionals analysis in precancerous lesions and squamous cell carcinoma
- 2014 - 2017 The mechanism of development of tumor-associated macrophage in oral squamous cell carcinoma
- 2013 - 2016 The role of the Mediator complexes in transcriptional regulation of the chemokine genes
- 2010 - 2014 Analysis of the inhibitory mechanisms of IFN gamma induced gene expression by hypoxia
- 2009 - 2011 Regulatory mechanisms of gene expression in anti-inflammatory M2 macrophages
- 2008 - 2009 Transcriptional repression of interferon-gamma-inducible gene by hypoxia
- 2006 - 2007 低酸素によるインターフェロン・ガンマー誘導性遺伝子発現の抑制機構の解析
Show all
Papers (23): -
Ari Matsumoto, Miki Hiroi, Kazumasa Mori, Nobuharu Yamamoto, Yoshihiro Ohmori. Differential Anti-Tumor Effects of IFN-Inducible Chemokines CXCL9, CXCL10, and CXCL11 on a Mouse Squamous Cell Carcinoma Cell Line. Medical sciences (Basel, Switzerland). 2023. 11. 2
-
Ryosuke Ushio, Miki Hiroi, Ari Matsumoto, Kazumasa Mori, Nobuharu Yamamoto, Yoshihiro Ohmori. Enhanced Cytotoxic Effects in Human Oral Squamous Cell Carcinoma Cells Treated with Combined Methyltransferase Inhibitors and Histone Deacetylase Inhibitors. Biomedicines. 2022. 10. 4
-
Hana Yamaguchi, Miki Hiroi, Kazumasa Mori, Ryosuke Ushio, Ari Matsumoto, Nobuharu Yamamoto, Jun Shimada, Yoshihiro Ohmori. Simultaneous Expression of Th1- and Treg-Associated Chemokine Genes and CD4+, CD8+, and Foxp3+ Cells in the Premalignant Lesions of 4NQO-Induced Mouse Tongue Tumorigenesis. Cancers. 2021. 13. 8
- Hana Yamaguchi, Miki Hiroi, Yoshihiro Ohmori. Silencing of the interferon-inducible gene Ifi204/p204 induces resistance to interferon-γ-mediated cell growth arrest of tumor cells. Cytokine. 2019. 118. 80-92
-
Iguchi M, Hiroi M, Kanegae H, Ohmori Y. Costimulation of Murine Osteoblasts with Interferon-γ and Tumor Necrosis Factor-α Induces Apoptosis through Downregulation of Bcl-2 and Release of Cytochrome c from Mitochondria. Mediators of inflammation. 2018. 2018. 3979606
more... MISC (9): -
山口 花, 廣井 美紀, 大森 喜弘. マウス扁平上皮癌細胞のIFN耐性における細胞増殖制御遺伝子のDNAメチル化による発現抑制. Journal of Oral Biosciences Supplement. 2014. 2014. 200-200
-
廣井 美紀, 山口 花, 大森 喜弘. IL-4による一酸化窒素合成酵素遺伝子NOS2の発現抑制機構. Journal of Oral Biosciences Supplement. 2013. 2013. 211-211
-
山口 花, 廣井 美紀, 大森 喜弘. マウス扁平上皮癌細胞におけるIFNγ耐性機構. Journal of Oral Biosciences Supplement. 2013. 2013. 212-212
- 天野滋, 関根圭輔, 廣井美紀, 大森喜弘. 破骨細胞分化に関与する核内リン酸化蛋白質の2次元電気泳動解析. Journal of Oral Biosciences. 2007. 49. Supplement
-
廣井 美紀, 大森 喜弘. p38 MAP kinaseは転写因子STAT1、NF-κBのクロストークによる相乗的な転写活性を制御する. Journal of oral biosciences. 2004. 46. 5. 416-416
more... Awards (3): - 2005/10 - International Cytokine Society Ed Leonard Prize Fund for Chemotaxis/Chemokine Research
- 2004/10 - 歯科基礎医学会 優秀ポスター賞
- 2004/10 - 歯科基礎医学会 歯科基礎医学会賞
Return to Previous Page