2011 - 2016 Regulation of polarity signaling during morphogenesis, remodeling, and breakdown of epithelial tubular structure
2011 - 2016 肝細胞誘導におけるダイレクトリプログラミング機構の解明とその応用
2013 - 2015 肝臓における細胞分化の破綻と疾患の発症をつなぐ分子機構の解明
2011 - 2015 Molecular mechanism underlying maintenance and differentiation of tissue-specific stem cells
2013 - 2014 細胞リプログラミングにおける細胞増殖の意義に関する研究
2010 - 2012 Molecular mechanism underlying liver stem cell system
2010 - 2011 肝炎による肝未分化細胞の発生とその発癌への影響に関する研究
2008 - 2011 肝細胞分化関連遺伝子の導入による皮膚細胞からの肝細胞作製技術
2006 - 2007 ジェネティックリネージトレーシング法を用いた成体肝幹細胞の同定
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Papers (68):
Shizuka Miura, Kenichi Horisawa, Tokuko Iwamori, Satoshi Tsujino, Kazuya Inoue, Satsuki Karasawa, Junpei Yamamoto, Yasuyuki Ohkawa, Sayaka Sekiya, Atsushi Suzuki. Hepatocytes differentiate into intestinal epithelial cells through a hybrid epithelial/mesenchymal cell state in culture. Nature communications. 2024. 15. 1. 3940-3940
Takehiro Yamamoto, Tetsu Hayashida, Yohei Masugi, Kiyotaka Oshikawa, Noriyo Hayakawa, Mai Itoh, Chiyoko Nishime, Masami Suzuki, Aiko Nagayama, Yuko Kawai, et al. PRMT1 Sustains De Novo Fatty Acid Synthesis by Methylating PHGDH to Drive Chemoresistance in Triple-Negative Breast Cancer. Cancer Research. 2024. 84. 7. 1065-1083
Kenichi Horisawa, Shizuka Miura, Hiromitsu Araki, Fumihito Miura, Takashi Ito, Atsushi Suzuki. Transcription factor-mediated direct cellular reprogramming yields cell-type specific DNA methylation signature. Scientific Reports. 2023. 13. 1. 22317
Kenichi Horisawa, Atsushi Suzuki. The role of pioneer transcription factors in the induction of direct cellular reprogramming. Regenerative Therapy. 2023. 24. 112-116