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J-GLOBAL ID：200901096392251133 Update date: Jan. 22, 2025

Seiichi Saito

サイトウセイイチ | Seiichi Saito

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Affiliation and department：
Job title： Professor

Research field (1)： Urology

Research keywords (5)： prostate cancer , Stage-specific embryonic antigen-4 (SSEA-4) , Sialyltransferase ST3Gal 2 , Glycobiology , genitourinary cancer

Research theme for competitive and other funds (35)：

2022 - 2023 Exploration of serum markers for patients with castration-resistant prostate cancer
2020 - 2023 前立腺癌の悪性度に関わる幹細胞マーカーSSEA-4の役割
2019 - 2022 Non invasive estimation of renal fibrosis using MRI and texture analysis
2017 - 2020 Growth inhibition effect of the sialidase inhibitor of influenza antiviral drugs in cancer cell lines.
2016 - 2019 Research on markers expressed in high-grade prostate cancer

2016 - 2019 Biological Role and Clinical Significance of Decreased Glycoprotein in Renal Cancer Serum

2014 - 2017 Investigation of novel diagnostic biomarkers for prostate cancer based on RM2 antigen

2013 - 2016 Search for new urothelial cancer biomarkers

2013 - 2016 The glycoprotein carrying sialyl T as a possible marker for renal cell carcinoma

2012 - 2013 糖鎖変化を標的とした泌尿器系癌の血清および尿中マーカー開発

2011 - 2013 A novel urinary marker for detection of urothelial carcinoma The clinical significance and the biological role of 80KDa glycoprotein

2009 - 2011 Dose a novel biomarker, RM2-Haptoglobin-beta, has the possibility to exceed PSA in predicting outcome of prostate cancer?

2009 - 2011 The analysis of glycoprotein react to the monoclonal antibody RM2 in urine of urothelial carcinoma cases.

2008 - 2010 Functional role of haptoglobin-β chain defined by RM2 in prostate cancer cells

2005 - 2008 Novel therapy for muscle invasive bladder cancer using glyco-biological approach

2004 - 2007 大学発ベンチャー創出推進平成17年度課題「スフィンゴリピッドの体外診断薬・治療薬への開発」

2006 - 2007 機能性先端装置一体中空ファイバ型レーザバイポーラ

2005 - 2007 Construction of high reliability and ultra-thin medical laser endoscope

2005 - 2006 New therapy for renal cell carcinoma with down regulation of glycosyltransferase gene

2005 - 2006 悪性度を反映する新しい前立腺癌マーカーRM2抗原の血清レベル測定

2004 - 2005 高機能低侵襲レーザバイポーラー

2003 - 2005 The roles of sialyltransferases involved in malignant progression of renal cell carcinoma

2004 - 2004 最小侵襲レーザ医療用中空ファイバ・先端装置の国際標準化

2002 - 2004 Glycotherapy for renal cell carcinoma

2002 - 2004 再燃前立腺がん治療におけるQOL評価と経済評価を統合した意志決定支援ツールの開発

2001 - 2002 Multifunctional laser-delivery system for all types of medical lasers

2000 - 2000 シアリダーゼ遺伝子による細胞リモデリング

1999 - 1999 シアリダーゼ遺伝子による細胞リモデリングとその臨床応用

1998 - 1999 Disialosyl galactosyl globoside as an adhesion molecule expressed on renal and lung cancer cells and its relationship to adrenal gland metastatic potential

1998 - 1999 腎癌転移関連糖鎖の研究:免疫担当細胞上の糖鎖レセプターを介する免疫抑制の可能性

1997 - 1999 Expression cloning of sialyltransferase involved in malignant progression of human RCC

1998 - 1998 シアリダーゼ遺伝子による細胞リモデリングとその臨床応用

1996 - 1996 腎癌の転移,増殖に関与するTGF-βおよびTGF-βリセプターの発現に関する研究

1995 - 1995 腎細胞癌の糖鎖変化と転移性に関する研究:globo-series gangliosideと接着、免疫系との関連

1994 - 1994 泌尿器系癌における糖鎖変化と悪性度に関する研究-FH6認識糖蛋白の分析-

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Papers (233)：

Shotaro Nakanishi, Tetsuji Suda, Kei Tanaka, Tomoko Yonamine, Kenji Numahata, Ai Sugawa, Takuma Oshiro, Yoshinori Oshiro, Seiichi Saito, Junichi Inokuchi. MUC1 expression is associated with ST3GAL2 and negatively correlated with the androgen receptor in castration-resistant prostate cancer. Glycoconjugate Journal. 2024. 41. 381-394
Shotaro Nakanishi, Masato Goya, Tetsuji Suda, Tomoko Yonamine, Ai Sugawa, Seiichi Saito. Increased level of serum leucine-rich-alpha-2-glycoprotein 1 in patients with clear cell renal cell carcinoma. BMC urology. 2024. 24. 1. 94-94
Ryu Kimura, Keiichiro Izumi, Kei Tanaka, Yoshinori Oshiro, Seiichi Saito. Ex Vivo Partial Nephrectomy and Autotransplantation for Complex and Multifocal Renal Cell Carcinoma at a Single Institution: A Case Series. Cureus. 2024. 16. 2. e53686
Shotaro Nakanishi, Yumi Fukushima, Junichi Inokuchi, Tomoaki Hakariya, Hiroaki Kakinoki, Hideki Enokida, Katsuaki Chikui, Hirofumi Matsuoka, Toshitaka Shin, Shoichiro Mukai, et al. Clinicopathological characteristics of adrenocortical carcinoma in the Kyushu-Okinawa area of Japan. International journal of urology : official journal of the Japanese Urological Association. 2024
Takahiro Yamaguchi, Masato Goya, Katsuyoshi Higashijima, Shohei Tobu, Ryuta Sato, Shuichi Tatarano, Shoichiro Mukai, Kei-Ichiro Uemura, Katsunori Tatsugami, Kazuna Tsubouchi, et al. Real-world treatment outcomes of patients with penile cancer in the Kyushu-Okinawa area of Japan in the pre-guideline era. Japanese journal of clinical oncology. 2023

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MISC (208)：

與那嶺智子, 仲西昌太郎, 斎藤誠一, 宮里実. NR5A1遺伝子変異を伴う46,XY性分化疾患の双子の症例. 日本小児泌尿器科学会雑誌. 2021. 30. 1. 106-106
Hirofumi Matsuoka, Kazuna Tsubouchi, Masatoshi Tanaka, Nobuhiro Haga, Takanori Yamaguchi, Yasuhiro Koikawa, Minoru Miyazato, Seiichi Saito, Toshiharu Kihara, Yasuyoshi Miyata, et al. Factors affecting the long-term postoperative prognosis of reflux nephropathy: 18Th Kyushu cooperative urological research. Nishinihon Journal of Urology. 2021. 82. 86. 570-578
與那嶺智子, 宮里実, 仲西昌太郎, 斎藤誠一. 二分脊椎に伴う神経因性膀胱に対して回腸利用膀胱拡大術を施行した症例の検討. 日本小児泌尿器科学会雑誌. 2020. 29. 2. 240-240
大湾知子, 渡真利絹江, 宮里実, 當山悦子, 新崎真由美, 高良奈津子, 長嶺覚子, 南部路治, 泉惠一朗, 芦刈明日香, et al. 多職種で取り組む排泄ケア看護師の立場から. 日本排尿機能学会誌. 2020. 31. 1. 123-123
芦刈明日香, 長嶺覚子, 泉惠一朗, 木村隆, 大城琢磨, 斎藤誠一, 宮里実. ラット脊髄における選択的オピオイドμ受容体アゴニスト[D-Ala2、NMe-Phe4、Gly-ol5]-enkephalinの尿道尿禁制反射に対する効果. 日本排尿機能学会誌. 2020. 31. 1. 274-274

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Patents (2)：

前立腺癌のための血清マーカー
前立腺癌における抗がん剤の薬剤耐性を抑制するための組成物

Books (12)：

Urologic Surgery Next オープンサージャリー
メジカルビュー社 2019 ISBN:9784758313339
腎臓症候群(第2版)上 -その他の腎臓疾患を含めて-
別冊日本臨床新領域別症候群シリーズ No. 17 2012
【腎・泌尿器癌基礎・臨床研究のアップデート】
日本臨床 2010
EBM泌尿器科疾患の治療2009-2010
中外医学社 2009
講義録泌尿器科学
2007

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Lectures and oral presentations (104)：

Ex vivo partial nephrectomy and autotransplantation for multiple renal cell carcinomas associated with VHL disease.
(2023)
Expression of ST3GAL2-associated markers in sera of patients with castration-resistant prostate cancer.
(2023)
尿中ラクトフェリン膀胱癌マーカーとしての有用性について
(第109回日本泌尿器科学会総会 2021)
泌尿器科ロボット手術プロクター制度の現状と問題点
(第34回日本内視鏡外科学会総会、神戸 2021)
膠芽腫と去勢抵抗性前立腺癌に共通発現する幹細胞マーカーSSEA-4
(第24回日本臨床脳神経外科学会、沖縄 2021)

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Education (2)：

1977 - 1983 Tohoku University Faculty of Medicine
1974 - 1977 神奈川県立横須賀高校

Work history (6)：

2024/04 - 現在 University of the Ryukyus
2010/04 - 2024/03 Graduate School of Medicine, University of the Ryukyus, Professor
2008/08 - 2010/03 Faculty of Medicine, School of Medicine, Department of Organ-Oriented Medicine, University of the Ryukyus, Professor
2002/10 - 2008/08 Tohoku University Graduate School of Medicine Department of Urology Associate Professor
1993/04 - 2002/09 Tohoku University Hospital Department of Urology Assistant Professor

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Association Membership(s) (5)：

米国泌尿器科学会 , 日本泌尿器内視鏡学会 , 日本癌学会 , 日本癌治療学会 , 日本泌尿器科学会

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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