Rchr
J-GLOBAL ID:200901097137805725   Update date: Sep. 15, 2024

Sugase Kenji

スガセ ケンジ | Sugase Kenji
Affiliation and department:
Job title: Full Professor
Homepage URL  (1): https://researchmap.jp/read0006511/
Research keywords  (6): E-NMR ,  NMR ,  Biophysics ,  Structural Biology ,  Rheo-NMR ,  protein aggregation
Research theme for competitive and other funds  (37):
  • 2024 - 2028 Investigation of molecular aggregation control mechanism by solution environment and creation of molecular design tools
  • 2024 - 2026 動的溶液環境のセンシングおよび液-液相分離の制御と計測
  • 2022 - 2026 Development of analytical platform for proteins in electric field and its application
  • 2024 - 2025 流れに対するバイオ医薬品の安定性を定量評価できる装置開発補助事業
  • 2022 - 2025 Promoting Dynamic Solution Science
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Papers (100):
  • Chisato Nishizawa, Shunsuke Aburaya, Yuishin Kosaka, Kenji Sugase, Wataru Aoki. Optimizing in vitro expression balance of central dogma-related genes using parallel reaction monitoring. Journal of Bioscience and Bioengineering. 2024
  • Tomoki Sorada, Erik Walinda, Masahiro Shirakawa, Kenji Sugase, Daichi Morimoto. An integrated approach of NMR experiments and MD simulations visualizes structural dynamics of a cyclic multi-domain protein. Protein Science. 2023. 32. 10
  • Yusuke Shuto, Erik Walinda, Daichi Morimoto, Kenji Sugase. Conformational Fluctuations and Induced Orientation of a Protein, Its Solvation Shell, and Bulk Water in Weak Non-Unfolding External Electric Fields. The Journal of Physical Chemistry B. 2023. 127. 34. 7417-7430
  • Erik Walinda, Kenji Sugase, Naoki Ishii, Masahiro Shirakawa, Kazuhiro Iwai, Daichi Morimoto. Solution structure of the HOIL-1L NZF domain reveals a conformational switch regulating linear ubiquitin affinity. Journal of Biological Chemistry. 2023. 105165-105165
  • Crowded environments affect structural fluctuations and abnormal aggregation of proteins. 2023. 55. 5. 42-45
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MISC (33):
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Patents (2):
  • 剪断流を発生させる器具
  • 剪断流を発生させる器具
Books (6):
  • タンパク質の構造解析手法と In silicoスクリーニングへの応用事例 ~AlphaFold、In silico創薬、NMR、X線、クライオ電子顕微鏡~
    技術情報協会 2023
  • NMRによる有機材料分析とその試料前処理、データ解釈
    技術情報協会 2021 ISBN:9784861048609
  • Experimental Approaches of NMR Spectroscopy
    Springer 2018 ISBN:9789811059667
  • 揺らぎ・ダイナミクスと生体機能 物理化学的視点から見た生体分子
    化学同人 2013
  • Handbook of Oxytocin Research: Synthesis, Storage and Release, Actions and Drug Forms
    Nova Science Publishers 2009
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Lectures and oral presentations  (58):
  • Rheo-NMRによる アミロイド線維化過程のリアルタイム計測
    (第42回 日本認知症学会学術集会 2023)
  • 動的溶液環境下の タンパク質の動的構造
    (基雕加5学最新NMR解析法 第7回ワークショップ タンパク質のダイナミクスと機能 2023)
  • NMRによる動的溶液環境に応答する天然変性タンパク質の動的構造解析
    (2022年度 中性子構造生物学研究会「天然変性タンパク質」 2023)
  • High-sensitivity Rheo-NMR
    (The 7th International Symposium on Drug Discovery and Design by NMR 2022)
  • Mechanism of amyloid fibrillation of a protein driven by flow-induced physical perturbation
    (Joint Meeting of the 20th KIAS Conference on "Protein Structure and Function" 2022)
more...
Professional career (1):
  • Doctor (Engineering) (Yokohama National University)
Work history (10):
  • 2022/04 - 現在 Kyoto University Division of Applied Life Sciences, Graduate School of Agriculture Full Professor
  • 2015/02 - 2022/03 Kyoto University Department of Molecular Engineering, Graduate School of Engineering Associate Professor
  • 2018/04 - 2019/03 Osaka University Institute for Protein Research
  • 2011/01 - 2015/01 Suntory Foundation for Life Sciences Bioorganic Research Institute NMR Group Leader, Senior Researcher
  • 2009/04 - 2015/01 Kobe University Graduate School of Engineering Visiting Associate Professor
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Committee career (2):
  • 2023/05 - 現在 日本農芸化学会 関西支部参与会
  • 2023/03 - 現在 日本生物物理学会 会誌編集委員
Awards (1):
  • 2017/10 - 日本学術振興会 審査委員の表彰
Association Membership(s) (4):
日本農芸化学会 ,  日本生物物理学会 ,  The Nuclear Magnetic Resonance Society of Japan ,  PROTEIN SCIENCE SOCIETY OF JAPAN
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