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J-GLOBAL ID：200901098542640454 Update date: Oct. 26, 2024

Imai Toshio

イマイトシオ | Imai Toshio

Affiliation and department：

Research field (4)： Experimental pathology , Veterinary medicine , Environmental effects of chemicals , Environmental effects of radiation

Research keywords (4)： Experimental Pathology , Carcinogenesis , 毒性病理学 , Toxicologic Pathology

Research theme for competitive and other funds (4)：

2015 - 2018 腫瘍性病変をエンドポイントとするオルガノイド系を用いる食品添加物等の遺伝毒性・発がん性の短期包括的試験法の開発
2011 - 2013 食習慣の乳腺発がんに及ぼす影響に関する研究
2003 - 2011 アクリルアミドの発がん性に関する研究
2008 - 2010 Immunofluorescence imaging analysis for intra- and inter-cellular signal transduction mechanisms in chemical carcinogenesis models

Papers (95)：

堀美香, 前田康喜, 今井俊夫, 筆宝義隆, 豊國伸哉, 林良敬. グルカゴン遺伝子欠損マウスで自然発症する膵内分泌腫瘍の解析(Analysis of spontaneous pancreatic endocrine tumors in Gcggfp/gfp mice). 日本癌学会総会記事. 2023. 82回. 181-181
Toshio Imai, Hiroshi Yoshida, Yukino Machida, Mizuki Kuramochi, Hitoshi Ichikawa, Takashi Kubo, Mami Takahashi, Tomoyasu Kato. Alteration in molecular properties during establishment and passaging of endometrial carcinoma patient-derived xenografts. Scientific Reports. 2023. 13. 1
Toshio Imai, Mie Naruse, Yukino Machida, Gen Fujii, Michihiro Mutoh, Masako Ochiai, Mami Takahashi, Hitoshi Nakagama. Feeding a High-Fat Diet for a Limited Duration Increases Cancer Incidence in a Breast Cancer Model. Nutrition and Cancer. 2022. 1-13
Toshio Imai, Mie Naruse, Masako Ochiai, Kenji Matsumoto, Satsuki Ikeda, Manami Kani, Yuyu Kato, Akiyoshi Hirayama, Tomoyoshi Soga, Yusaku Hori, et al. Different types of reactions to E7386 among colorectal cancer patient-derived organoids and corresponding CAFs. Oncology letters. 2022. 24. 1. 221-221
Rikako Ishigamori, Mie Naruse, Akihiro Hirata, Yoshiaki Maru, Yoshitaka Hippo, Toshio Imai. The potential of organoids in toxicologic pathology: Histopathological and immunohistochemical evaluation of a mouse normal tissue-derived organoid-based carcinogenesis model. Journal of toxicologic pathology. 2022. 35. 3. 211-223

MISC (30)：

今井俊夫, 成瀬美衣, 石ケ守里加子, 高橋真美. 免疫不全マウス皮下移植によるマウス乳がんの多様な分化. 日本癌学会学術総会抄録集(Web). 2021. 80th
高橋真美, 石ケ守里加子, 尾野雅哉, 平岡伸介, 今井俊夫. 膵がん患者由来ゼノグラフトモデルにおける高脂肪食による腫瘍の増殖促進及び関連遺伝子・タンパク質発現の変化に関する検討. 日本癌学会学術総会抄録集(Web). 2021. 80th
泉谷昌志, 吉原靖典, 丸喜明, 落合雅子, 松浦哲也, 今井俊夫, 筆宝義隆. 変異遺伝子のin vitro再構成による胆管細胞発がんの誘導(Induced Tumorigensis by in vitro Reconstitution of Genetic Alterations in Biliary Tract Cells). 日本癌学会総会記事. 2018. 77回. 1524-1524
今井俊夫, 成瀬美衣, 落合雅子, 筆宝義隆. マウス正常上皮組織由来オルガノイドの化学発がん物質に対する反応性. がん予防学術大会プログラム・抄録集. 2018. 2018. 38
松浦哲也, 加藤真吾, 落合雅子, 今井俊夫, 中島淳, 筆宝義隆. in vitroモデルが明らかにするマウス膵管発がんにおける微小環境の重要性. 日本癌学会総会記事. 2017. 76回. P-2280

Books (3)：

Education (4)：

- 1987 Obihiro University of Agriculture and Veterinary Medicine
- 1987 Obihiro University of Agriculture and Veterinary Medicine Graduate School, Division of Animal Sciences Veterinary Medicine
- 1985 Obihiro University of Agriculture and Veterinary Medicine Faculty of Animal Husbandry School of Veterinary Medicine
- 1985 Obihiro University of Agriculture and Veterinary Medicine Faculty of Animal Science Veterinary Medicine

Professional career (2)：

Work history (4)：

Committee career (5)：

Awards (1)：

Association Membership(s) (6)：

THE JAPANESE SOCIETY OF TOXICOLOGY , 米国毒性病理学会(Society of Toxicologic Pathologists) , 日本癌学会 , 日本病理学会 , 日本獣医学会 , 日本毒性病理学会

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