Rchr
J-GLOBAL ID:200901098764091122
Update date: Feb. 26, 2024
Motizuki Mitsuyoshi
モチヅキ ミツヨシ | Motizuki Mitsuyoshi
Affiliation and department:
Research field (1):
Cell biology
Research keywords (6):
Smad
, TGF-beta
, Cell motility
, antimicrobial peptide
, endocytosis
, Yeast
Research theme for competitive and other funds (9):
- 2010 - 2012 TGF-betaシグナルの細胞応答選択的な制御手法の研究
- 1996 - 1997 酵母を用いた時間生物学:生物時計と自食死の分子細胞生物学的解析
- 1993 - 1995 酵母における生物時計の遺伝学的、分子生物学的研究
- 1989 - 1990 Transcriptional Regulation of Eukaryotic Ribosomal Protein Genes and Function of the Proteins.
- 1987 - 1987 アフリカツメガエルを用いたリボソーム蛋白質の核への輸送に関する研究
- 1986 - 1986 真核細胞におけるリボソーム蛋白質の代謝と発現における調節機構
- Structure-Functional Study on Apolipoprotein
- Structure-Functional Study on Antimicrobial peptide
- Study on Yeast Scenescence
Show all
Papers (28):
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Mitsuyoshi Motizuki, Takashi Yokoyama, Masao Saitoh, Keiji Miyazawa. The Snail signaling branch downstream of the TGF-β/Smad3 pathway mediates Rho activation and subsequent stress fiber formation. 2023. 300. 1. 105580
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Mitsuyoshi Motizuki, Daizo Koinuma, Takashi Yokoyama, Yuka Itoh, Chiho Omata, Kohei Miyazono, Masao Saitoh, Keiji Miyazawa. TGF-β-induced cell motility requires downregulation of ARHGAPs to sustain Rac1 activity. Jounal of Biological Chemistry. 2021. 296. 100545
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Naoko Nakano, Nobuo Sakata, Yuki Katsu, Daiki Nochise, Erika Sato, Yuta Takahashi, Saori Yamaguchi, Yoko Haga, Souichi Ikeno, Mitsuyoshi Motizuki, et al. Dissociation of the AhR/ARNT complex by TGF-β/Smad signaling represses CYP1A1 gene expression and inhibits benze[a]pyrene-mediated cytotoxity. Jounal of Biological Chemistry. 2020. 295. 27. 9033-9051
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Yuka Itoh Y, Daizo Koinuma, Chiho Omata, Tomohiro Ogami, Mitsuyoshi Motizuki, So-ichi Yaguchi, Takuma Itoh, Kunio Miyake, Shuichi Tsutsumi, Hiroyuki Aburatani, et al. A comparative analysis of Smad-responsive motifs identifies multiple regulatory inputs for TGF-β transcriptional activation. Jounal of Biological Chemistry. 2019. 294. 42. 15466-15479
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Mitsuyoshi Motizuki, Masao Saitoh, Keiji Miyazawa. Maid is a negative regulator of transforming growth factor-beta-induced cell migration. Journal of Biochemistry. 2015. 158. 5. 435-444
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MISC (1):
Patents (1):
Books (1):
Lectures and oral presentations (11):
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合成ペプチドを用いたSmad3の機能領域の同定
(第75回 日本癌学会学術総会 2016)
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Determination of functional domains by using synthetic peptide blockers
(2015)
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TGF-betaによる運動性の促進に必要なSmad-Olig1転写複合体はPin1によって制御されている
(生化学関東支部例会 2013)
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TGF-betaによる運動性の促進に必要なSmad-Olig1転写複合体はPin1によって制御されている
(第71回 日本癌学会学術総会 2012)
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Olig1は、TGF-betaによる運動性の促進を制御するSmad cofactorである
(第70回 日本癌学会学術総会 2011)
more...
Education (3):
- - 1984 Niigata University
- - 1984 Niigata University Graduate School, Division of Medicine
- - 1978 Niigata University Faculty of Science
Professional career (2):
Work history (2):
- 2002/10 - 山梨大学助手(生化学講座第2教室)
- 1984/04 - 山梨医科大学助手(生化学第2)
Association Membership(s) (3):
THE JAPANESE CANCER ASSOCIATION
, 日本進化学会
, 日本生化学会
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