Rchr
J-GLOBAL ID：200901099162500257   Update date: Jun. 22, 2024

Saiki Shinji

サイキ シンジ | Saiki Shinji
Affiliation and department：
University of Tsukuba Department of Neurology

About University of Tsukuba Department of Neurology


Job title： Professor
Research field  (1)： Neurology
Research keywords  (8)： 代謝産物 ,  バイオマーカー ,  オートファジー ,  細胞生物学 ,  パーキンソン病 ,  臨床神経学 ,  Basal ganglia ,  Clinical neurology
Research theme for competitive and other funds  (38)：
  • 2023 - 2027 New strategy for preventing colorectal cancer by targeting polyamines, which are thought to be carcinogens
  • 2023 - 2026 細胞内alpha-Synuclein凝集制御機構を解析するケミカルバイオロジー
  • 2022 - 2025 Development of anti-Parkinson's disease drugs enhancing neuronal autophagy
  • 2022 - 2024 パーキンソン病発症起点としてのmicrobiome-gut連関機構の解明
  • 2021 - 2024 Elucidation of transmission and aggregation mechanisms of alpha-synuclein as a major component of Lewy body and development of disease-modifying therapies for synucleinopathies
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Papers (118)：
  • Yuki Date, Yukiko Sasazawa, Mitsuhiro Kitagawa, Kentaro Gejima, Ayami Suzuki, Hideyuki Saya, yasuyuki kida, Masaya Imoto, Eisuke Itakura, Nobutaka Hattori, et al. Novel autophagy inducers by accelerating lysosomal clustering against Parkinson's disease. eLife. 2024. 13
  • Tetsushi Kataura, Lucia Sedlackova, Congxin Sun, Gamze Kocak, Niall Wilson, Peter Banks, Faisal Hayat, Sergey Trushin, Eugenia Trushina, Oliver D. K. Maddocks, et al. Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease models. Cell Death & Disease. 2024. 15. 5
  • Tao Hu, Hayato Itoh, Masahiro Oda, Shinji Saiki, Nobutaka Hattori, Koji Kamagata, Wataru Sako, Kei-ichi Ishikawa, Shigeki Aoki, Kensaku Mori. Boosting substantia nigra segmentation from T2 weighted MRI via test-time normalization and distance-reweighted loss. Medical Imaging 2024: Computer-Aided Diagnosis. 2024
  • Haruka Takeshige-Amano, Taku Hatano, Koji Kamagata, Christina Andica, Takashi Ogawa, Atsuhiko Shindo, Wataru Uchida, Wataru Sako, Shinji Saiki, Yasushi Shimo, et al. Free-water diffusion magnetic resonance imaging under selegiline treatment in Parkinson's disease. Journal of the Neurological Sciences. 2024. 457
  • Haruka Takeshige-Amano, Taku Hatano, Koji Kamagata, Christina Andica, Takashi Ogawa, Atsuhiko Shindo, Wataru Uchida, Wataru Sako, Shinji Saiki, Yasushi Shimo, et al. Free-water diffusion magnetic resonance imaging under selegiline treatment in Parkinson's disease. Journal of the neurological sciences. 2024. 457. 122883-122883
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MISC (104)：
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Patents (6)：
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Education (1)：
  • - 1999 Kyoto Prefectural University of Medicine
Professional career (1)：
  • 博士(医学) (順天堂大学)
Work history (6)：
  • 2023/01 - 現在 University of Tsukuba
  • 2021/06 - 2022/12 Juntendo University Department of Neurology Associate Professor
  • 2011/04 - 2021/05 Juntendo University
  • 2008/03 - 2011/03 Juntendo University
  • 2005/07 - 2008/03 Cambridge Institute for Medical Reseach 研究員
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Awards (4)：
  • 2023/06 - 順天堂大学医師会 順天堂大学医師会賞
  • 2021/03 - - A metabolic profile of polyamines in Parkinson disease: A promising biomarker
  • 2005 - British Council Japan Association 留学助成
  • 2005 - 2005 Pergolide Fellowship for Eli Lilly Japan K.K.
Association Membership(s) (8)：
日本神経化学会 ,  日本脳卒中学会 ,  日本神経科学学会 ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  Movement Disorder Society ,  American Academy of Neurology ,  日本内科学会 ,  日本神経学会
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