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J-GLOBAL ID：200901099417161567 Update date: Feb. 16, 2025

Kanai Motomu

カナイモトム | Kanai Motomu

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www.f.u-tokyo.ac.jp/~kanai/index.html

Research field (1)： Pharmaceuticals - chemistry and drug development

Research keywords (2)：有機化学 , Organic Chemistry

Research theme for competitive and other funds (44)：

2023 - 2027 Elucidation of the role of autophagy in photo-oxygenated amyloid degradation
2021 - 2024 Chemical glycan modification of membrane proteins for "manipulating" membrane dynamics
2020 - 2024 生体分子の構造変換ダイナミズムに介入する化学触媒研究
2022 - 2023 分子合成オンデマンドを実現するハイブリッド触媒系の創製
2020 - 2023 超高性能クライオEMの分子プローブ創製

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Papers (231)：

Ryo Kuroda, Eisho Toyama, Tomoya Sugai, Maho Imai, Kohei Watanabe, Natsuki Konoue, Katsuya Maruyama, Mio Kondo, Shigeyuki Masaoka, Tsuyoshi Saitoh, et al. Electrochemical Tryptophan-Selective Bioconjugation. 2025
Cheng Peng, Tianle Wu, Xueyan Yang, Mengyao Pei, Siyuan Wang, Motomu Kanai, Yohei Shimizu, Xiaofeng Wei. Copper(I)-Catalyzed Asymmetric Nucleophilic Addition to Aldehydes with Skipped Enynes. Organic Letters. 2024. 26. 47. 10072-10077
Tomoyuki Fukuta, Toshifumi Tatsumi, Kohei Fujiyoshi, Takashi Koyama, Shigehiro A Kawashima, Harunobu Mitsunuma, Kenzo Yamatsugu, Motomu Kanai. Umpolung Phosphorylation of Tyrosine via 1,2-Phospha-Brook Rearrangement. Organic letters. 2024. 26. 41. 8827-8831
Yuki Yamanashi, Shinpei Takamaru, Atsushi Okabe, Satoshi Kaito, Yuto Azumaya, Yugo Kamimura, Kenzo Yamatsugu, Tomoya Kujirai, Hitoshi Kurumizaka, Atsushi Iwama, et al. Chemical catalyst manipulating cancer epigenome and transcription. 2024
Tamiko Nozaki, Mayu Onoda, Misuzu Habazaki, Yuma Takeuchi, Hisashi Ishida, Yuko Sato, Tomoya Kujirai, Kayo Hanada, Kenzo Yamatsugu, Hitoshi Kurumizaka, et al. Logics for Developing Regioselective Histone Acetylating Catalysts. 2024

MISC (316)：

福田智之, 藤吉浩平, 川島茂裕, 三ツ沼治信, 三ツ沼治信, 山次健三, 金井求. Umpolung phosphorylation of tyrosine toward protein/peptide modification. 日本薬学会年会要旨集(Web). 2024. 144th
山根三奈, 梅田大輝, 豊邉萌, 岩井篤志, 工藤玄己, 三ツ沼治信, 三ツ沼治信, 堀由起子, 富田泰輔, 岡田匡充, et al. Small Molecule Catalysts Function as Amyloid Breakers in vivo via Photooxygenation of Transthyretin Amyloids. 日本薬学会年会要旨集(Web). 2024. 144th
有井優, CHEN Hongyu, 三ツ沼治信, 三ツ沼治信, 金井求. Catalytic Allylation of Ketones Using Unactivated Alkenes. 日本化学会春季年会講演予稿集(Web). 2024. 104th
井上丈司, 山次健三, 三ツ沼治信, 三ツ沼治信, 金井求. Development of catalytic chemo-selective decarboxylation of aspartic acid. 日本化学会春季年会講演予稿集(Web). 2024. 104th
金井求, 生長幸之助, 豊邉萌. レドックス活性を利用した抗体修飾と応用. MEDCHEM NEWS. 2023. 33. 1. 33-37

Patents (2)：

Education (4)：

Professional career (2)：

Work history (9)：

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Awards (9)：

2022/07 - 産経新聞社独創性を拓く先端技術大賞社会人部門特別賞アミロイド選択的光酸素化技術によるアミロイド病態治療 ~アルツハイマー病、さらにはアミロイドーシスの根本治療法開発を目指して~
2022/03 - Nagoya Silver Medal
2016 - トムソン・ロイター第4回リサーチフロントアワード
2011 - Novartis Lecturer in Organic Chemistry (2011年)
2005 - Merck-Banyu Lectureship Award

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Association Membership(s) (4)：

アメリカ化学会 , 有機合成化学協会 , 日本化学会 , 日本薬学会

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