YOSHIAKI NAKAYAMA

ナカヤマヨシアキ | YOSHIAKI NAKAYAMA

Affiliation and department：
Homepage URL (1)： https://www.kobepharma-u.ac.jp/micro-s/index.html

Research field (4)： Immunology , Pharmaceuticals - health and biochemistry , Molecular biology , Functional biochemistry

Research keywords (5)：免疫学 , Macrophages , Erythrocytes , 神経科学 , 糖鎖生物学

Research theme for competitive and other funds (8)：

2020 - 2023 分泌型ヘムタンパク質によるマクロファージの貪食抑制機構の解明
2015 - 2019 Functional analysis of orphan glycosyltransferases involved in mucin-type O-glycosylation in the brain
2015 - 2018 Clarification of molecular mechanisms that are involved in onset of epilepsy, depression, and anxiety.
2015 - 2018 The novel roles of O-glycans in hypothalamus-pituitary axis
2013 - 2015 Functional analysis of macropinocytosis in cancer cells under poor nutrientional status

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Papers (34)：

Yoshiaki Nakayama, Yuki Masuda, Ryohei Shimizu, Morichika Konishi. Neudesin, a secretory protein, attenuates activation of lipopolysaccharide-stimulated macrophages by suppressing the Jak/Stat1/iNOS pathway. Life Sciences. 2024. 358. 123185-123185
Yuki Masuda, Naoto Kondo, Yoshiaki Nakayama, Ryohei Shimizu, Morichika Konishi. Neudesin regulates dendritic cell function and antitumor CD8+ T cell immunity. Clinical immunology (Orlando, Fla.). 2024. 110376-110376
Hironari Nishizawa, Mitsuyo Matsumoto, Mie Yamanaka, Riko Irikura, Kazuma Nakajima, Keisuke Tada, Yoshiaki Nakayama, Morichika Konishi, Nobuyuki Itoh, Ryo Funayama, et al. BACH1 inhibits senescence, obesity, and short lifespan by ferroptotic FGF21 secretion. Cell reports. 2024. 43. 7. 114403-114403
Yoshiaki Nakayama, Yuki Masuda, Takehiro Mukae, Tadahisa Mikami, Ryohei Shimizu, Naoto Kondo, Hiroshi Kitagawa, Nobuyuki Itoh, Morichika Konishi. A secretory protein neudesin regulates splenic red pulp macrophages in erythrophagocytosis and iron recycling. Communications biology. 2024. 7. 1. 129-129
Yuki Masuda, Shizuka Yamashita, Yoshiaki Nakayama, Ryohei Shimizu, Morichika Konishi. Maitake Beta-Glucan Enhances the Therapeutic Effect of Trastuzumab via Antibody-Dependent Cellular Cytotoxicity and Complement-Dependent Cytotoxicity. Biological & pharmaceutical bulletin. 2024. 47. 4. 840-847

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MISC (57)：

森本優樹, 中山喜明, 増田有紀, 清水涼平, 伊藤信行, 小西守周. 分泌タンパク質neudesinは炎症性マクロファージに作用しJak/Stat/iNOS経路を抑制する. 日本薬学会年会要旨集. 2022. 142年会. 26PO5-03S
安田奨, 岡優希, 増田有紀, 清水涼平, 中山喜明, 伊藤信行, 小西守周. Fgf21は胸腺髄質上皮細胞の分化成熟を促進し、樹状細胞への組織特異的自己抗原の移行を誘導することで、中枢性免疫寛容に貢献する. 日本薬学会年会要旨集. 2022. 142年会. 28PO6-01S
藤本祥文, 薦田哲志, 増田有紀, 清水涼平, 中山喜明, 伊藤信行, 小西守周. 食餌性肥満とニコチンによって誘発される筋萎縮と代謝変化におけるFgf21の生理的意義. 日本薬学会年会要旨集. 2022. 142年会. 28PO9-03S
西山侑志, 稲岡浩輝, 上村祐毅, 米田茉希子, 中山喜明, 増田有紀, 伊藤信行, 小西守周. 炎症時のマクロファージにおける分泌因子Neudesinの役割の検討. 日本薬学会年会要旨集. 2021. 141年会. 29P01-088S
谷垣拓海, 高間哲也, 村田亜津紀, 松前憲幸, 阿部佑亮, 増田有紀, 中山喜明, 伊藤信行, 小西守周. 分泌因子Neudesinは樹状細胞の活性を抑制することで、がんの成長を促進する. 日本薬学会年会要旨集. 2021. 141年会. 29P01-089S

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Books (2)：

enetic Diseases Associated with Protein Glycosylation Disorders in Mammals
2013
The FGF Family in Humans, Mice, and Zebrafish: Development, Physiology, and Pathophysiology
Human Genetic Diseases 2011

Education (2)：

Professional career (1)：

Work history (4)：

Association Membership(s) (3)：

THE PHARMACEUTICAL SOCIETY OF JAPAN , THE JAPANESE SOCIETY OF CARBOHYDRATE RESEARCH , 日本分子生物学会

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