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J-GLOBAL ID:201001039942066468   Update date: Mar. 06, 2025

Taru Hidenori

タル ヒデノリ | Taru Hidenori
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Affiliation and department:
Job title: Associate Professor
Research field  (4): Developmental biology ,  Cell biology ,  Neuroscience - general ,  Pharmaceuticals - health and biochemistry
Research keywords  (6): 老化 ,  神経変性疾患 ,  線虫 ,  C. elegans ,  シナプス ,  神経
Research theme for competitive and other funds  (5):
  • 2020 - 2023 神経プレシナプス電位依存性カルシウムチャネルの局在制御分子機構
  • 2016 - 2020 Regulation of neuronal adaptor molecules by voltage-gated calcium channels at presynaptic structures
  • 2013 - 2017 線虫セロトニン作動性神経細胞HSNにおけるプレシナプス形成分子機構の全体像
  • 2011 - 2013 プレシナプス形成におけるSYD-1・SYD-2の機能と神経細胞内輸送制御
  • 2009 - 2011 神経プレシナプス形成のアダプター分子SYD-2による制御機構
Papers (29):
  • Keiko Honda, Hiroo Takahashi, Saori Hata, Ruriko Abe, Takashi Saito, Takaomi C Saido, Hidenori Taru, Yuriko Sobu, Kanae Ando, Tohru Yamamoto, et al. Suppression of the amyloidogenic metabolism of APP and the accumulation of Aβ by alcadein α in the brain during aging. Scientific reports. 2024. 14. 1. 18471-18471
  • Yuzuha Shiraki, Monet Mitsuma, Ritsuko Takada, Saori Hata, Akira Kitamura, Shinji Takada, Masataka Kinjo, Hidenori Taru, Ulrike C Müller, Tohru Yamamoto, et al. Axonal transport of Frizzled5 by Alcadein α-containing vesicles is associated with kinesin-1. Molecular biology of the cell. 2023. 34. 11. ar110
  • Saori Hata, Haruka Saito, Takeharu Kakiuchi, Dai Fukumoto, Shigeyuki Yamamoto, Kensaku Kasuga, Ayano Kimura, Koichi Moteki, Ruriko Abe, Shungo Adachi, et al. Brain p3-Alcβ peptide restores neuronal viability impaired by Alzheimer's amyloid β-peptide. EMBO molecular medicine. 2023. 15. 5. e17052
  • Keiko Honda, Yuhki Saito, Haruka Saito, Megumi Toyoda, Ruriko Abe, Takashi Saito, Takaomi C Saido, Makoto Michikawa, Hidenori Taru, Yuriko Sobu, et al. Accumulation of amyloid-β in the brain of mouse models of Alzheimer's disease is modified by altered gene expression in the presence of human apoE isoforms during aging. Neurobiology of aging. 2023. 123. 63-74
  • Saori Hata, Kuniyuki Kano, Kazunori Kikuchi, Shoichi Kinoshita, Yuriko Sobu, Haruka Saito, Takashi Saito, Takaomi C Saido, Yoshitake Sano, Hidenori Taru, et al. Suppression of amyloid-β secretion from neurons by cis-9, trans-11-octadecadienoic acid, an isomer of conjugated linoleic acid. Journal of neurochemistry. 2021. 159. 3. 603-617
more...
MISC (41):
  • 中川健斗, 鈴木利治, 多留偉功. Role of synaptic transmission in lifespan regulation through neuropeptide secretion in C. elegans. 日本薬学会年会要旨集(Web). 2024. 144th
  • 中川健斗, 石川智規, 鈴木利治, 多留偉功. Complementary effects of SYD-2/Liprin-α on lifespan regulation through neuropeptide secretion in C. elegans. 日本薬学会年会要旨集(Web). 2023. 143rd
  • 宮沢桃子, 中島愛弓, 鈴木利治, 多留偉功. Analysis of the interaction between DLK, a regulator of axonal development, and kinesin-1 motor. 日本薬学会年会要旨集(Web). 2023. 143rd
  • 櫛引 勇人, 鈴木 利治, 多留 偉功. 線虫においてアダプタータンパク質RIM-binding proteinとRIMは冗長的に電位依存性Ca2+チャネルのプレシナプス局在を制御する. 日本薬学会年会要旨集. 2020. 140年会. 28L-am08S
  • 多留 偉功. 神経機能発現機構の最前線: 神経単位の遺伝子発現制御とタンパク質の階層的かつ冗長的機能を探る 神経プレシナプス形成における階層的かつ冗長的なアダプター分子群の制御機能. 日本生化学会大会プログラム・講演要旨集. 2019. 92回. [1S17a-02]
more...
Patents (1):
Books (1):
  • タンパク質がわかる
    羊土社 2003
Lectures and oral presentations  (1):
  • Hierarchical and redundant regulation of presynaptic assembly by multiple adaptor molecules
    (The 92nd annual meeting of the Japanese biochemical society 2019)
Education (2):
  • - 2002 The University of Tokyo Graduate School of Pharmaceutical Sciences
  • - 1997 The University of Tokyo Faculty of Pharmaceutical Sciences Department of Pharmacy
Professional career (1):
  • Ph.D. (The University of Tokyo)
Work history (8):
  • 2015/04 - 現在 Hokkaido University Faculty of Pharmaceutical Sciences Associate Professor
  • 2013/04 - 2015/03 Hokkaido University Faculty of Pharmaceutical Sciences Lecturer
  • 2008/10 - 2013/03 Hokkaido University Creative Research Institution Project Assistant Professor
  • 2008/04 - 2008/09 University of California, San Diego Assistant Specialist
  • 2007/01 - 2008/03 University of California, San Diego Postdoctoral Fellow
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Committee career (2):
  • 2013/09 - 2023/12 American Society for Biochemistry and Molecular Biology Editorial Board Member for the Journal of Biological Chemistry
  • 2013/07 - 2016/02 日本薬学会北海道支部 幹事
Association Membership(s) (5):
THE JAPANESE BIOCHEMICAL SOCIETY ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  American Society for Biochemistry and Molecular Biology ,  Society for Neuroscience
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