Research field (4)：
Developmental biology
, Cell biology
, Neuroscience - general
, Pharmaceuticals - health and biochemistry
Research keywords (6)：
老化
, 神経変性疾患
, 線虫
, C. elegans
, シナプス
, 神経
Research theme for competitive and other funds (5)：
2020 - 2023 神経プレシナプス電位依存性カルシウムチャネルの局在制御分子機構
2016 - 2020 Regulation of neuronal adaptor molecules by voltage-gated calcium channels at presynaptic structures
2013 - 2017 線虫セロトニン作動性神経細胞HSNにおけるプレシナプス形成分子機構の全体像
2011 - 2013 プレシナプス形成におけるSYD-1・SYD-2の機能と神経細胞内輸送制御
2009 - 2011 神経プレシナプス形成のアダプター分子SYD-2による制御機構
Papers (28)：
Yuzuha Shiraki, Monet Mitsuma, Ritsuko Takada, Saori Hata, Akira Kitamura, Shinji Takada, Masataka Kinjo, Hidenori Taru, Ulrike C Müller, Tohru Yamamoto, et al. Axonal transport of Frizzled5 by Alcadein α-containing vesicles is associated with kinesin-1. Molecular biology of the cell. 2023. 34. 11. ar110
Keiko Honda, Yuhki Saito, Haruka Saito, Megumi Toyoda, Ruriko Abe, Takashi Saito, Takaomi C Saido, Makoto Michikawa, Hidenori Taru, Yuriko Sobu, et al. Accumulation of amyloid-β in the brain of mouse models of Alzheimer's disease is modified by altered gene expression in the presence of human apoE isoforms during aging. Neurobiology of aging. 2023. 123. 63-74
Saori Hata, Kuniyuki Kano, Kazunori Kikuchi, Shoichi Kinoshita, Yuriko Sobu, Haruka Saito, Takashi Saito, Takaomi C Saido, Yoshitake Sano, Hidenori Taru, et al. Suppression of amyloid-β secretion from neurons by cis-9, trans-11-octadecadienoic acid, an isomer of conjugated linoleic acid. Journal of neurochemistry. 2021. 159. 3. 603-617
Saori Hata, Anqi Hu, Yi Piao, Tadashi Nakaya, Hidenori Taru, Maho Morishima-Kawashima, Shigeo Murayama, Masaki Nishimura, Toshiharu Suzuki. Enhanced amyloid-β generation by γ-secretase complex in DRM microdomains with reduced cholesterol levels. Human molecular genetics. 2020. 29. 3. 382-393
Hierarchical and redundant regulation of presynaptic assembly by multiple adaptor molecules
(The 92nd annual meeting of the Japanese biochemical society 2019)
Education (2)：
- 2002 The University of Tokyo Graduate School of Pharmaceutical Sciences
- 1997 The University of Tokyo Faculty of Pharmaceutical Sciences Department of Pharmacy
Professional career (1)：
Ph.D. (The University of Tokyo)
Work history (8)：
2015/04 - 現在 Hokkaido University Faculty of Pharmaceutical Sciences Associate Professor
2013/04 - 2015/03 Hokkaido University Faculty of Pharmaceutical Sciences Lecturer
2008/10 - 2013/03 Hokkaido University Creative Research Institution Project Assistant Professor
2008/04 - 2008/09 University of California, San Diego Assistant Specialist
2007/01 - 2008/03 University of California, San Diego Postdoctoral Fellow
2005/04 - 2007/03 JSPS Overseas Research Fellow
2004/04 - 2006/12 University of California, Santa Cruz Postdoctoral Fellow
2002/04 - 2004/03 Hokkaido University Faculty of Pharmaceutical Sciences Postdoctoral Fellow
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Committee career (2)：
2013/09 - 現在 米国生化学分子生物学会 Journal of Biological Chemistry誌 編集委員
2013/07 - 2016/02 日本薬学会北海道支部 幹事
Association Membership(s) (5)：
THE JAPANESE BIOCHEMICAL SOCIETY
, THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
, THE PHARMACEUTICAL SOCIETY OF JAPAN
, American Society for Biochemistry and Molecular Biology
, Society for Neuroscience
