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J-GLOBAL ID：201001044028571620 Update date: Mar. 19, 2025

Kobayashi Takeshi

Research field (1)： Cell biology

Research theme for competitive and other funds (12)：

2021 - 2024 Analysis of mechanosensing/transduction in costamere by ultrasound
2021 - 2024 Imaging analysis of ER-mitochondria contact sites in living cells
2019 - 2022 Mechano-nutrition-signaling for disuse muscle atrophy
2018 - 2021 Imaging analysis of mechno-sensing in mitochondria of living cells
2015 - 2020 Mechanosensing Mechanisms for Sensing Mechanical Stress Including Gravitational Changes

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Papers (55)：

Muscle atrophy and mitochondrial Ca#U2+#UR levels in model organisms. Precision Medicine. 2023. 6. 8. 65-68
Atsushi Higashitani, Mika Teranishi, Yui Nakagawa, Yukou Itoh, Surabhi Sudevan, Nathaniel J. Szewczyk, Yukihiko Kubota, Takaaki Abe, Takeshi Kobayashi. Cover Image. The FASEB Journal. 2023
Atsushi Higashitani, Mika Teranishi, Yui Nakagawa, Yukou Itoh, Surabhi Sudevan, Nathaniel J. Szewczyk, Yukihiko Kubota, Takaaki Abe, Takeshi Kobayashi. Increased mitochondrial Ca2+ contributes to health decline with age and Duchene muscular dystrophy in C. elegans. The FASEB Journal. 2023
小林剛, 田中瑞奈, 寺西美佳, 東谷篤志. ミトコンドリアにおける機械刺激受容. 細胞. 2023. 55. 2. 55-58
Yusuke Kawamura, Tetsuro Hida, Bisei Ohkawara, Masaki Matsushita, Takeshi Kobayashi, Shinya Ishizuka, Hideki Hiraiwa, Satoshi Tanaka, Mikito Tsushima, Hiroaki Nakashima, et al. Meclozine ameliorates skeletal muscle pathology and increases muscle forces in mdx mice. Biochemical and Biophysical Research Communications. 2022

Lectures and oral presentations (12)：

動物細胞の重力変化に対する感知・応答機構
(日本宇宙生物科学会第38回大会・シンポジウム3「動物細胞や線虫の重力刺激に対する感知・応答機構」 2024)
Mechano-sensing of mitochondria in cultured animal cells
(International Symposium on Mechanobiology for Human Health 2023)
Towards understanding the gravity sensing in single cells
(2021)
Cell Gravisensing Project
(2021)
Substrate rigidity sensing of mesenchymal stem cells by utilizing Trpv4 channels
(2020)

Work history (3)：

2015/06/01 - 現在 Nagoya University Graduate School of Medicine Program in Integrated Medicine Cell Science Lecturer
2010/04/01 - 2015/05/31 Nagoya University Program in Cellular Information Medicine Assistant Professor
2007/04/01 - 2010/03/31 Nagoya University Graduate School of Medicine Researcher

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