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J-GLOBAL ID:201001085063695399   Update date: Feb. 03, 2025

Hirotaka Kuwata

クワタ ヒロタカ | Hirotaka Kuwata
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Affiliation and department:
Homepage URL  (1): https://sites.google.com/view/showaoralmicrobiology/
Research field  (1): Oral medicine (pathology)
Research keywords  (2): oral microbiota ,  mucosal immunology
Research theme for competitive and other funds  (9):
  • 2018 - 2022 Functional analysis of oral dysbiosis associated with inflammatory bowel disease
  • 2017 - 2021 Elucidation of the regulatory mechanisms for bacterial virulence with small RNAs.
  • 2015 - 2019 Analysis of suppression effects of food allergy elicited by oral bacteria
  • 2016 - 2018 Inhibition of denture plaque deposition on complete dentures by 2-methacryloyloxyethyl phosphorylcholine polymer coating
  • 2016 - 2018 The Basic Research to The development of Immaculate Denture with The Visible light Curing Device
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Papers (58):
  • Mai Nara, Mie Kurosawa, Momoe Itsumi, Hirobumi Morisaki, Haruka Fukamachi, Nobuo Okahashi, Noriyuki Suzuki, Hirotaka Kuwata. Experimental Murine Periodontitis Increases Salivary Gland IgA-Producing B Cells Following Oral Dysbiosis. Microbiology and Immunology. 2025
  • Natsuno Nakamura, Hirobumi Morisaki, Momoe Itsumi, Nobuo Okahashi, Haruka Fukamachi, Ayako Sato, Miki Kadena, Mariko Kikuchi, Shohei Matsui, Takahiro Funatsu, et al. Inflammasome regulation by the cell surface ecto-5'-nucleotidase of the oral commensal, Streptococcus oralis. Biochemical and biophysical research communications. 2024. 744. 151206-151206
  • Suguru Miki, Haruka Fukamachi, Momoe Itsumi, Nagatoshi Fujiwara, Takashi Takaki, Mie Kurosawa, Hirobumi Morisaki, Noriyuki Suzuki, Hirotaka Kuwata. The Klebsiella mannose phosphotransferase system promotes proliferation and the production of extracellular polymeric substances from mannose, facilitating adaptation to the host environment. Journal of oral biosciences. 2024
  • Manami Hayashi, Mina Mori, Momoe Itsumi, Natsuno Nakamura, Takashi Takaki, Kaoru Onoyama, Haruka Fukamachi, Mie Kurosawa, Hirobumi Morisaki, Takahiro Funatsu, et al. Severity of acute lung injury in aspiration pneumonia model mice transplanted with human oral microflora. Oral Science International. 2023
  • 林 真奈美, 森 美菜, 逸見 百江, 黒澤 実愛, 深町 はるか, 森崎 弘史, 桑田 啓貴. ヒト口腔細菌叢移植マウスの急性肺障害誘導による誤嚥性肺炎マウスモデルの作製. 日本細菌学雑誌. 2023. 78. 1. 95-95
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MISC (78):
  • 逸見 百江, Trtic Natasa, 森 美菜, 松井 庄平, 中村 夏野, 深町 はるか, 黒澤 美愛, 森崎 弘史, 桑田 啓貴. 口腔内細菌叢は口腔粘膜での好中球の末梢分化に関与している. Journal of Oral Biosciences Supplement. 2023. 2023. [O2-04]
  • 森美菜, 林真奈美, 中村夏野, 逸見百江, 黒澤実愛, 深町はるか, 森崎弘史, 桑田啓貴. The role of commensal microflora on the neutrophil differentiation in the oral mucosal membrane. 日本細菌学雑誌(Web). 2023. 78. 1
  • 林真奈美, 森美菜, 逸見百江, 黒澤実愛, 深町はるか, 森崎弘史, 桑田啓貴. Aspiration pneumonia mice model induced by acute lung injury with human oral flora transplantation. 日本細菌学雑誌(Web). 2023. 78. 1
  • 三木優, 三木優, 深町はるか, 逸見百江, 森崎弘史, 黒澤実愛, 桑田啓貴. Klebsiellaのマンノースホスホトランスフェラーゼシステムは腸管定着関連因子である. Journal of Oral Biosciences Supplement (Web). 2023. 2023
  • 三木優, 三木優, 深町はるか, 逸見百江, 森崎弘史, 黒澤実愛, 桑田啓貴. Role of mannose phosphotransferase system on intestinal colonization of Klebsiella. 日本生体防御学会学術総会講演抄録集. 2023. 34th
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Education (2):
  • 1997 - 2001 Osaka University Graduate School of Dentistry
  • 1991 - 1997 Osaka university, Department of dentistry
Professional career (1):
  • PhD, D.D.S. (Osaka University)
Work history (6):
  • 2012/12 - 現在 Showa univeristy, department of dentistry Professor
  • 2010/02 - 2012/11 Kyoto university, Institute for virus research Research associate
  • 2007/01 - 2010/01 Hospital for sick children, Toronto Postgraduate researcher
  • 2004/03 - 2006/12 Kyushu University, Medical institute of bioregulation Research associate
  • 2002/02 - 2004/02 理化学研究所 研究員
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Association Membership(s) (4):
日本口腔科学会 ,  JAPANESE ASSOCIATION FOR ORAL BIOLOGY ,  JAPANESE SOCIETY FOR BACTERIOLOGY ,  THE JAPANESE SOCIETY FOR IMMUNOLOGY
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