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J-GLOBAL ID：201101001400913717 Update date: Dec. 12, 2024

Sasaki-Hamada Sachie

Research field (1)： Neuroscience - general

Research keywords (3)：経鼻製剤 , 神経ペプチド , 精神・神経疾患の病態と治療

Research theme for competitive and other funds (6)：

2024 - 2027 オキシトシンに着目した遅発性産後うつ病の病態解明
2018 - 2021 A physiological role for Neuromedin U in the hippocampal neuronal network and the application
2016 - 2020 Study on the low body weight in young adult rats with neonatal dopamine depletion
2015 - 2018 Pharmacological and translational studies of centrally-acting peptide derivatives specialized in the delivery to the brain by the intranasal administration
2012 - 2015 Pharmacological research on antidepressant-like effects of GLP-2 on refractory depression.

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Papers (36)：

Sachie Sasaki-Hamada, Arisa Hara, Yume Tainaka, Sho Satoh, Jun-Ichiro Oka, Hitoshi Ishibashi. Isoform-specific distribution of 14-3-3 proteins in the hippocampus of streptozotocin-induced diabetic rats. Neuroscience letters. 2024. 843. 138027-138027
Hayuma Otsuka, Sachie Sasaki-Hamada, Hitoshi Ishibashi, Jun-Ichiro Oka. Hippocampal acetylcholine receptor activation-dependent long-term depression in streptozotocin-induced diabetic rats. Neuroscience letters. 2024. 822. 137650-137650
Junpei Takahashi, Yudai Ueta, Daisuke Yamada, Sachie Sasaki-Hamada, Takashi Iwai, Tomomi Akita, Chikamasa Yamashita, Akiyoshi Saitoh, Jun-Ichiro Oka. Intracerebroventricular administration of oxytocin and intranasal administration of the oxytocin derivative improve β-amyloid peptide (25-35)-induced memory impairment in mice. Neuropsychopharmacology reports. 2022
Sachie Sasaki-Hamada, Emi Sanai, Mariko Kanemaru, Gaku Kamanaka, Jun-Ichiro Oka. Long-term exposure to high glucose induces changes in the expression of AMPA receptor subunits and glutamate transmission in primary cultured cortical neurons. Biochemical and biophysical research communications. 2022. 589. 48-54
Sachie Sasaki-Hamada, Yoshimichi Maeno, Mizuki Yabe, Hitoshi Ishibashi. Neuromedin U modulates neuronal excitability in rat hippocampal slices. Neuropeptides. 2021. 89. 102168-102168

MISC (9)：

Funane Taichi, Sasaki-Hamada Sachie, Horiguchi Michiko, Nakao Yusuke, Sasaki Rie, Yamashita Chikamasa, Oka Jun-Ichiro. The intranasally administered neuromedin U derivative induced memory improvement. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2016. 130. 3. S230
Jun-Ichiro Oka, Sachie Sasaki-Hamada, Michiko Horiguchi, Ryuji Nakamura, Yusuke Nakao, Chikamasa Yamashita. Therapeutic potential of the intranasally administered GLP-2 derivative for the treatment of depression. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2016. 130. 3. S53-S53
Kinzo Matsumoto, Yimin Niu, Qi Zhao, Hironori Fujiwara, Sachie Hamada, Jun-Ichiro Oka. Chotosan and cognitive deficits attributable to aging and diabetes. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 51-51
Banri Segawa, Hiroaki Sacai, Sachie Hamada, Jun-Ichiro Oka. Effects of memantine, a NMDA receptor antagonist, on learning behavior and synaptic plasticity in juvenile diabetes mellitus rats. 2012. 118. 140-140
Azusa Sugiyama, Akiyoshi Saitoh, Misa Yamada, Takashi Iwai, Tomio Hashimoto, Yuya Makino, Masanori Ohashi, Sachie Hamada, Jun-Ichiro Oka, Masatoshi Inagaki, et al. Riluzole produces distinct anxiolytic-like effects in rats through blockade of voltage-activated sodium channels. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2012. 118. 68-68

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